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页码: 37/5368 每页显示数量

WDR5 remodels NANOG condensates to drive transcriptional programs and sustain stem cell identity

Authors: Duo Wang, Xianle Shi, Jiaying Xie, Lijie Zhao, Bin Wu, Qiman Dong, Yaoguang Huang, Jinlong Suo, Xinyu Wang, Beixuan He, Shukun Yan, Hongjuan Xue, Yuheng Shi, Yingbin Liu, Jianlong Wang, Yong Chen, Yanjing Li

Journal: Nature Communications

PubMed ID: 41565645

Doi: 10.1038/s41467-026-68623-w

Products & Services: Custom DNA/RNA Oligos

An integrated valved microfluidic platform for rapid and simultaneous nucleic acid detection

Authors: Zihan Wang, Fuwan Yang, Shuai Zeng, Rui Sun, Qifei Hu, Yichen Du

Journal: Lab on a chip

PubMed ID: 41439322

Doi: 10.1039/D5LC01096A

Products & Services: Synthetic Guide RNA

Genetic engineering of systemically injectable oncolytic viruses for pyroptosis-accelerated cancer virotherapy

Authors: Xiaohong Chen, Minqi Yang, Yuxuan Chen, Yao Zhang, Shuang Wang, Jiaqi Meng, Zunqiao Zhu, Wen Li, Wei Wei, Yuan Ping, Tingbo Liang

Journal: Nature cancer

PubMed ID: 41545714

Doi: 10.1038/s43018-025-01078-y

Products & Services: Synthetic Guide RNA

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Authors: Tyler N. Starr; Allison J. Greaney; Cameron M. Stewart; Alexandra C. Walls; William W. Hannon; David Veesler; Jesse D. Bloom; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok

Journal: PLOS Pathogens

PubMed ID: 36399443

Doi: 10.1371/journal.ppat.1010951

Molecular mechanism of ziresovir targeting the fusion glycoprotein of respiratory syncytial virus

Authors: Mengrong Yan; Jingjing Zou; Zhao Gao; Haiqing Yuan; Jim Zhen Wu; Gang Zou; Fengjiang Liu; Wei Peng

Journal: PLOS Pathogens

PubMed ID: 41576151

Doi: 10.1371/journal.ppat.1013864

Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure

Authors: Chen Xiang; Kaja Arusha; Danielle Springer; Sachiko Nakamori; Ping Du Jiang; Zhi-Hong Yang; Jing Cui; Yu Zhang; Huie Jing; Ann Y. Park; Maria H. Zhu; Sarah E. Weber; Deniz Cagdas; Hassan Abolhassan; Nasrin Behniafard; Margery G. Smelkinson; Qihui Liang; Elif Everest; Julia F. Kun; Alyssa Grogan; Jennifer D. Treat; Christa S. Zerbe; Steven M. Holland; Renu Virmani; Alan T. Remaley; Helen C. Su; Lixin Zheng; Michael J. Lenardo

Journal: biorxiv

PubMed ID: 41743988

Doi: 10.64898/2026.01.26.701509

SARS-CoV-2 Mpro inhibitors from Siphonostegia chinensis : an integrated biophysical and computational study

Authors: Yingjie Ren; Wei Wang; Dai Zhang; Mingliang Zhang; Hui Zhang; Yali Wu; Feiyan Liu; Liuqing Yang; Pan Wang; Lei Chen; Xiaofei Chen; Jinfa Tang; Xianqing Ren

Journal: Frontiers in chemistry

PubMed ID: 42040628

Doi: 10.3389/fchem.2026.1790228

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Authors: Ting-Syuan Lin; Jingting Wan; Jingjin He; Shidong Cui; Yun Huang; Bojian Zhang; Hsi-Yuan Huang; Kexin Zhu; Jihang Chen; Tao Zhang; Shangfu Li; Liao Hu; Yongfei Wang; Hsien-Da Huang; Ping Tang; Yang-Chi-Dung Lin

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Journal: Pharmaceutics

PubMed ID: 41900810