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HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity

Authors: Lei Chu, Li Qian, Yu Chen, Shengnan Duan, Ming Ding, Wu Sun, Wei Meng, Juanjuan Zhu, Quanyi Wang, Haiping Hao, Chen Wang, Shufang Cui

Journal: Cell Reports

PubMed ID: 38421872

Doi: 10.1016/j.celrep.2024.113870

Products & Services: Recombinant Proteins

GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer

Authors: Zu Ye, Shengfeng Xu, Yin Shi, Xueqian Cheng, Yuan Zhang, Sunetra Roy, Sarita Namjoshi, Michael A Longo, Todd M Link, Katharina Schlacher, Guang Peng, Dihua Yu, Bin Wang, John A Tainer, Zamal Ahmed

Journal: Nature Communications

PubMed ID: 38459011

Doi: 10.1038/s41467-024-46283-y.

Products & Services: Peptide Synthesis

An oncolytic vaccinia virus encoding hyaluronidase reshapes the extracellular matrix to enhance cancer chemotherapy and immunotherapy

Authors: Shibing Wang, Yuxin Li, Chuning Xu, Jie Dong, Jiwu Wei

Journal: J Immunother Cancer

PubMed ID: 38458640

Doi: 10.1136/jitc-2023-008431

Products & Services: Recombinant Proteins

Design and Preclinical Evaluation of a Nanoparticle Vaccine against Respiratory Syncytial Virus Based on the Attachment Protein G

Authors: Richard Voorzaat, Freek Cox, Daan van Overveld, Lam Le, Lisanne Tettero, Joost Vaneman, Mark J G Bakkers, Johannes P M Langedijk

Journal: Vaccines (Basel)

PubMed ID: 38543928

Doi: 10.3390/vaccines12030294

Products & Services: Catalog Peptides

An Engineered Laccase from Accelerates Lignocellulose Degradation

Authors: Le Thanh Mai Pham, Kai Deng, Hemant Choudhary, Trent R Northen, Steven W Singer, Paul D Adams, Blake A Simmons, Kenneth L Sale

Journal: Biomolecules

PubMed ID: 38540744

Doi: 10.3390/biom14030324

Products & Services: Codon Optimization

In vitro digestion mimicking conditions in adults and elderly reveals digestive characteristics of pork from different cooking ways

Authors: Xiangyue Cao, Fan Zhao, Ziyi Lin, Xiaomei Sun, Xianming Zeng, Haoxi Liu, Yutong Li, Zihang Yuan, Yuan Su, Chong Wang, Guanghong Zhou

Journal: Food Res Int

PubMed ID: 38760136

Doi: 10.1016/j.foodres.2024.114204

Products & Services: Protein and Antibody Isolation

Antibody targeting of surface P-selectin glycoprotein ligand 1 leads to lymphoma apoptosis and tumorigenesis inhibition

Authors: João L Pereira, Francisca Ferreira, Nuno R Dos Santos

Journal: Hematol Oncol

PubMed ID: 38415859

Doi: 10.1002/hon.3257

Products & Services: Gene Synthesis

AIRE is expressed in breast cancer TANs and TAMs to regulate the extrinsic apoptotic pathway and inflammation

Authors: Eva Källberg, Meliha Mehmeti-Ajradini, Frida Björk Gunnarsdottir, Marcus Göransson, Caroline Bergenfelz, Roni Allaoui Fredriksson, Catharina Hagerling, Martin E Johansson, Charlotte Welinder, Karin Jirström, Karin Leandersson

Journal: J Leukoc Biol

PubMed ID: 38060995

Doi: 10.1093/jleuko/qiad152

Products & Services: Custom Vector Construction

Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography

Authors: Kaylen R Meeks, Juan Ji , Mykola V Protopopov , Olga O Tarkhanova , Yurii S Moroz , John J Tanner

Journal: J Chem Inf Model

PubMed ID: 38411104

Doi: 10.1021/acs.jcim.3c01879

Products & Services: Molecular Biology Reagents

A Synergistic Lipid Nanoparticle Encapsulating mRNA Shingles Vaccine Induces Potent Immune Responses and Protects Guinea Pigs from Viral Challenges

Authors: Xingdi Cheng 1 2, Sujia Liu 3, Jing Sun 4, Lin Liu 3, Xinghuan Ma 3, Jingjiao Li 1 2, Bangda Fan 3, Chen Yang 1 2, Yuanyuan Zhao 1 2, Shuai Liu 1, Yixing Wen 1 2, Wei Li 1 2, Simin Sun 1, Shiwei Mi 1 2, Haonan Huo 1 2, Lei Miao 5, Hao Pan 6, Xiaolan Cui 4, Jiaqi Lin 3, Xueguang Lu 1 2

Journal: Adv Mater

PubMed ID: 38145557

Doi: 10.1002/adma.20231088

Products & Services: Plasmid DNA Preparation