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Saikosaponin d protects pancreatic acinar cells against cerulein-induced pyroptosis through alleviating mitochondrial damage and inhibiting cGAS-STING pathway

Authors: Hui Chen, Xirong Lu, Beiqi Xu, Gang Cheng, Yuyi Li, Dan Xie

Journal: J Appl Toxicol

PubMed ID: 38462915

Doi: 10.1002/jat.4594

Products & Services: Gene Synthesis

Enhancing precision medicine: Bispecific antibody-mediated targeted delivery of lipid nanoparticles for potential cancer therapy

Authors: Yue Zhang, Xiaoyan Gu, Lili Huang, Yani Yang, Jun He

Journal: Int J Pharm

PubMed ID: 38467208

Doi: 10.1016/j.ijpharm.2024.123990

Products & Services: Molecular Biology Tools

Phoenixin 20 ameliorates pulmonary arterial hypertension via inhibiting inflammation and oxidative stress

Authors: Yaqin Chai, Xing Gu, HongJun Zhang, Xinting Xu, Lizhan Chen

Journal: Aging (Albany NY)

PubMed ID: 38517365

Doi: 10.18632/aging.205468

Products & Services: Custom DNA/RNA Oligos

4'--MethylbavachalconeB Targeted 14-3-3ζ Blocking the Integrin β3 Early Outside-In Signal to Inhibit Platelet Aggregation and Thrombosis

Authors: Ziqi Tang, Fanqi Lin, Zhiwen Chen, Boyang Yu, Ji-Hua Liu, Xiufeng Liu

Journal: J Agric Food Chem

PubMed ID: 38509000

Doi: 10.1021/acs.jafc.3c05211

Products & Services: Gene Synthesis

Long-term effects of Omicron BA2 breakthrough infection on immunity-metabolism balance: a 6-month prospective study

Authors: Yanhua Li, Shijie Qin, Lei Dong, Shitong Qiao, Xiao Wang, Dongshan Yu, Pengyue Gao, Yali Hou, Shouzhen Quan, Ying Li, Fengyan Fan, Xin Zhao, Yueyun Ma, George Fu Gao

Journal: Nat Commun

PubMed ID: 38503738

Doi: 10.1038/s41467-024-46692-z

Products & Services: Molecular Biology Reagents

Identification of mA RNA methylation genes in and expression profiling in response to different developmental and environmental stimuli

Authors: Mahbub Hasan, Zakia Sultana Nishat, Md Soyib Hasan, Tanvir Hossain, Ajit Ghosh

Journal: Biochem Biophys Rep

PubMed ID: 38511186

Doi: 10.1016/j.bbrep.2024.101677

Products & Services: Protein and Antibody Isolation

CIRP increases Foxp3 regulatory T cells and inhibits development of Th17 cells by enhancing TLR4-IL-2 signaling in the late phase of sepsis

Authors: Zongsheng Wu, Xu Liu, Wei Huang, Jing Chen, Songli Li, Jie Chao, Jianfeng Xie, Ling Liu, Yi Yang, Xiaojing Wu, Haibo Qiu

Journal: Int Immunopharmacol

PubMed ID: 38531201

Doi: 10.1016/j.intimp.2024.111924

Products & Services: Recombinant Proteins

Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity

Authors: Lucy Rutten, Maarten Swart, Annemart Koornneef, Pascale Bouchier, Sven Blokland, Ava Sadi, Jarek Juraszek, Aneesh Vijayan, Sonja Schmit-Tillemans, Johan Verspuij, Ying Choi, Chenandly E Daal, Aditya Perkasa, Shessy Torres Morales, Sebenzile K Myeni, Marjolein Kikkert, Jeroen Tolboom, Daniëlle van Manen, Harmjan Kuipers, Hanneke Schuitemaker, Roland Zahn, Johannes P M Langedijk

Journal: Sci Rep

PubMed ID: 38459086

Doi: 10.1038/s41598-024-56293-x

Products & Services: Codon Optimization

Atrogin-1 promotes muscle homeostasis by regulating levels of endoplasmic reticulum chaperone BiP

Authors: Avnika A Ruparelia, Margo Montandon, Jo Merriner, Cheng Huang, Siew Fen Lisa Wong, Carmen Sonntag, Justin P Hardee, Gordon S Lynch, Lee B Miles, Ashley Siegel, Thomas E Hall, Ralf B Schittenhelm, Peter D Currie

Journal: JCI Insight

PubMed ID: 38530354

Doi: 10.1172/jci.insight.167578

Products & Services: Molecular Biology Reagents

Mucosal tumor vaccination delivering endogenous tumor antigens protects against pulmonary breast cancer metastases

Authors: Friederike Oltmanns, Ana Vieira Antão, Pascal Irrgang, Vera Viherlehto, Leticia Jörg, Anna Schmidt, Jannik T Wagner, Michael Rückert, Ann-Sophie Flohr, Carol Imanuel Geppert, Benjamin Frey, Wibke Bayer, Claudia Gravekamp, Matthias Tenbusch, Udo Gaipl, Dennis Lapuente

Journal: J Immunother Cancer

PubMed ID: 38458636

Doi: 10.1136/jitc-2023-008652

Products & Services: Peptide Synthesis