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Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae

Authors: San Hadži, Zala Živič , Matic Kovačič , Uroš Zavrtanik , Sarah Haeserts, Daniel Charlier, Janez Plavec, Alexander N Volkov, Jurij Lah, Remy Loris

Journal: Nature Communications

PubMed ID: 38600130

Doi: 10.1038/s41467-024-47296-3

Products & Services: PCR Cloning and Subcloning

Structural basis for dimerization of a paramyxovirus polymerase complex

Authors: Jin Xie, Mohamed Ouizougun-Oubari, Li Wang, Guanglei Zhai, Daitze Wu, Zhaohu Lin, Manfu Wang, Barbara Ludeke, Xiaodong Yan, Tobias Nilsson, Lu Gao, Xinyi Huang, Rachel Fearns, Shuai Chen

Journal: Nature Communications

PubMed ID: 38605025

Doi: 10.1038/s41467-024-47470-7

Products & Services: Protein and Antibody Isolation

SARS-CoV-2 nsp15 preferentially degrades AU-rich dsRNA via its dsRNA nickase activity

Authors: Xionglue Wang, Bin Zhu

Journal: Nucleic Acids Res

PubMed ID: 38634805

Doi: 10.1093/nar/gkae290

Products & Services: Custom DNA/RNA Oligos

RBM22 regulates RNA polymerase II 5' pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5

Authors: Xian Du, Wenying Qin, Chunyu Yang, Lin Dai, Mingkui San, Yingdan Xia, Siyu Zhou, Mengyang Wang, Shuang Wu, Shaorui Zhang, Huiting Zhou, Fangshu Li, Fang He, Jingfeng Tang, Jia-Yu Chen, Yu Zhou, Rui Xiao

Journal: Genome Biology

PubMed ID: 38641822

Doi: 10.1186/s13059-024-03242-6

Products & Services: Catalog Antibodies

Oncolytic adenovirus encoding apolipoprotein A1 suppresses metastasis of triple-negative breast cancer in mice

Authors: Jie Dong, Lingkai Kong, Shiqun Wang, Mao Xia, Yenan Zhang, Jingyi Wu, Fuming Yang, Shuguang Zuo, Jiwu Wei

Journal: Experimental & Clinical Cancer Research

PubMed ID: 38566092

Doi: 10.1186/s13046-024-03011-0

Products & Services: Catalog Antibodies

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Authors: Victor E Cruz, Christine S Weirich, Nagesh Peddada, Jan P Erzberger

Journal: Nat Commun

PubMed ID: 38632236

Doi: 10.1038/s41467-024-47616-7

Products & Services: Gene Synthesis

Protein language models-assisted optimization of a uracil-N-glycosylase variant enables programmable T-to-G and T-to-C base editing

Authors: Yan He, Xibin Zhou, Chong Chang, Ge Chen, Weikuan Liu, Geng Li, Xiaoqi Fan, Mingsun Sun, Chensi Miao, Qianyue Huang, Yunqing Ma, Fajie Yuan, Xing Chang

Journal: Mol Cell

PubMed ID: 38377993

Doi: 10.1016/j.molcel.2024.01.021

Products & Services: Synthetic Guide RNA

Measles Virus-Based Vaccine Expressing Membrane-Anchored Spike of SARS-CoV-2 Inducing Efficacious Systemic and Mucosal Humoral Immunity in Hamsters

Authors: Zhi-Hui Yang 1, Yan-Li Song 1, Jie Pei 1, Song-Zhuang Li 1, Rui-Lun Liu 1, Yu Xiong 1, Jie Wu 1, Yuan-Lang Liu 1, Hui-Fen Fan 1, Jia-Hui Wu 1, Ze-Jun Wang 1, Jing Guo 1, Sheng-Li Meng 1, Xiao-Qi Chen 1, Jia Lu 1, Shuo Shen 1

Journal: Viruses

PubMed ID: 38675901

Doi: 10.3390/v16040559

Products & Services: Molecular Biology Reagents

A rational designed multi-epitope vaccine elicited robust protective efficacy against Klebsiella pneumoniae lung infection

Authors: Jingwen Liao, Xiaoli Zhang, Xi Zeng, Zhuo Zhao, Tianjun Sun, Zhenping Xia, Haiming Jing, Yue Yuan, Zhifu Chen, Qiang Gou, Liqun Zhao, Weijun Zhang, Quanming Zou, Jinyong Zhang

Journal: Biomed Pharmacother

PubMed ID: 38643540

Doi: 10.1016/j.biopha.2024.116611

Products & Services: Molecular Biology Reagents

Characterization of an O-Specific Glycosyltransferase Involved in Flagellin Glycosylation

Authors: Daisuke Fujinami, Ayumi Mizui, Azusa Miyata, Sohei Ito

Journal: ACS Chem Biol

PubMed ID: 38562012

Doi: 10.1021/acschembio.4c00045

Products & Services: Catalog Peptides