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A systematic analysis of affinity tags in the haloarchaeal expression system, for protein purification

Authors: Ram Karan, Dominik Renn, Thorsten Allers, Magnus Rueping

Journal: Front Microbiol

PubMed ID: 38873150

Doi: 10.3389/fmicb.2024.1403623

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CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice

Authors: Henriette Reventlow Frederiksen, Alexandra Glantz, Kåre Kryger Vøls, Søren Skov, Pernille Tveden-Nyborg, Kristine Freude, Ulrik Doehn

Journal: Front Genome Ed

PubMed ID: 38863835

Doi: 10.3389/fgeed.2024.1403395

Products & Services: Molecular Biology Reagents

Understanding the Enzyme ()-Norcoclaurine Synthase Promiscuity to Aldehydes and Ketones

Authors: Brunno A Salvatti, Marcelo A Chagas, Phillipe O Fernandes, Yan F X Ladeira, Aline S Bozzi, Veronica S Valadares, Ana Paula Valente, Amanda S de Miranda, Willian R Rocha, Vinicius G Maltarollo, Adolfo H Moraes

Journal: J Chem Inf Model

PubMed ID: 38776464

Doi: 10.1021/acs.jcim.3c01773

Products & Services: Molecular Biology Reagents

Therapeutic potentials of nonpeptidic V2R agonists for partial cNDI-causing V2R mutants

Authors: Ritsuki Kuramoto, Ryoji Kise, Mayu Kanno, Kouki Kawakami, Tatsuya Ikuta, Noriko Makita, Asuka Inoue

Journal: PLoS ONE

PubMed ID: 38748623

Doi: 10.1371/journal.pone.0303507

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Preamplification-free ultra-fast and ultra-sensitive point-of-care testing via LwaCas13a

Authors: Wanting Zeng, Wanping Chen, Yang Liu, Ting Zhang, Chao Zhai, Wenqiang Li, Longyu Wang, Cheng Zhang, Qili Zeng, Fei Wang, Lixin Ma

Journal: Biosens Bioelectron

PubMed ID: 38776799

Doi: 10.1016/j.bios.2024.116400

Products & Services: Protein and Antibody Isolation

The intrinsic substrate specificity of the human tyrosine kinome

Authors: Tomer M. Yaron-Barir, Brian A. Joughin, Emily M. Huntsman, Alexander Kerelsky, Daniel M. Cizin, Benjamin M. Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M. Orozco, Christina Schoenherr, Cari Sagum, Mark T. Bedford, R. Max Wynn, Shih-Chia Tso, David T. Chuang, Lei Li, Shawn S.-C. Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D. Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C. Frame, Peter V. Hornbeck, Lewis C. Cantley, Benjamin E. Turk, Michael B. Yaffe & Jared L. Johnson

Journal: Nature

PubMed ID: 38720073

Doi: 10.1038/s41586-024-07407-y

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Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin

Authors: Di Qu, Peng Ge, Laure Botella, Sae Woong Park, Ha-Na Lee, Natalie Thornton, James M. Bean, Inna V. Krieger, James C. Sacchettini, Sabine Ehrt, Courtney C. Aldrich & Dirk Schnappinger

Journal: Nat Commun

PubMed ID: 38755122

Doi: 10.1038/s41467-024-48448-1.

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Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding

Authors: Hongjun Bai, Eric Lewitus, Yifan Li, Paul V. Thomas, Michelle Zemil, Mélanie Merbah, Caroline E. Peterson, Thujitha Thuraisamy, Phyllis A. Rees, Agnes Hajduczki, Vincent Dussupt, Bonnie Slike, Letzibeth Mendez-Rivera, Annika Schmid, Erin Kavusak, Mekhala Rao, Gabriel Smith, Jessica Frey, Alicea Sims, Lindsay Wieczorek, Victoria Polonis, Shelly J. Krebs, Julie A. Ake, Sandhya Vasan, Diane L. Bolton, M. Gordon Joyce, Samantha Townsley & Morgane Rolland

Journal: Nat Commun

PubMed ID: 38724518

Doi: 10.1038/s41467-024-48139-x

Products & Services: Gene Synthesis

Structural basis for double-stranded RNA recognition by SID1

Authors: Runhao Wang, Ye Cong, Dandan Qian, Chuangye Yan, Deshun Gong

Journal: Nucleic Acids Res

PubMed ID: 38742627

Doi: 10.1093/nar/gkae395

Enhanced detection of ligand-PPARγ binding based on surface plasmon resonance through complexation with SRC1- or NCOR2-related polypeptide

Authors: Yiting Wang , Mingzhu Luo , Luyang Che , Qixin Wu , Jingzhe Li , Yanyan Ma , Jingyi Wang , Changzhen Liu

Journal: International Journal of Biological Macromolecules

PubMed ID: 38670200

Doi: 10.1016/j.ijbiomac.2024.131865

Products & Services: Gene Synthesis