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页码: 32/5357 每页显示数量

Structure of the Prenyltransferase in Bifunctional Copalyl Diphosphate Synthase from Penicillium fellutanum Reveals an Open Hexamer Conformation

Authors: Matthew N. Gaynes; Trey A. Ronnebaum; Kollin Schultz; Jacque L. Faylo; Ronen Marmorstein; David W. Christianson

Journal: Journal of structural biology

PubMed ID: 38184156

Doi: 10.1016/j.jsb.2023.108060

Products & Services: Plasmid DNA Preparation

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M pro and cathepsin L

Authors: Michael Dominic Sacco; Chunlong Ma; Panagiotis Lagarias; Ang Gao; Julia Alma Townsend; Xiangzhi Meng; Peter Dube; Xiujun Zhang; Yanmei Hu; Naoya Kitamura; Brett Hurst; Bart Tarbet; Michael Thomas Marty; Antonios Kolocouris; Yan Xiang; Yu Chen; Jun Wang

Journal: biorxiv

PubMed ID: 32766590

Doi: 10.1101/2020.07.27.223727

Enhanced Production of HCV E1E2 Subunit Vaccine Candidates via Protein-Protein Interaction Identification in Glycoengineered CHO cells

Authors: Mina Ying Min Wu; Frances Rocamora; Caressa M. Robinson; Seunghyeon Shin; Eric A. Toth; Thomas R. Fuerst; Svetlana Maurya; Nathan E. Lewis

Journal: biorxiv

PubMed ID: 40475571

Doi: 10.1101/2025.05.20.655202

A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

Products & Services: Catalog Antibodies

First inhibitor of a bacterial two-partner secretion system

Authors: Alfred Hartojo; Laurence Don Wai Luu; Lachlan Adamson; Kyra Majors; Ashleigh S. Paparella; Peggy A. Cotter; Richard M. Johnson; Matthew Thomas Doyle

Journal: biorxiv

PubMed ID: 41648283

Doi: 10.64898/2026.01.11.698920

Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo

Authors: Yancheng Liu; Shumin Tan; Lu Huang; Robert B. Abramovitch; Kyle H. Rohde; Matthew D. Zimmerman; Chao Chen; V ronique Dartois; Brian C. VanderVen; David G. Russell

Journal: The Journal of experimental medicine

PubMed ID: 27114608

Doi: 10.1084/jem.20151248

Products & Services: Endotoxin Detection & Removal System

IgG-Bridging–Seeded Synergistic Aggregation of SARS-CoV-2 Spikes Underlies Potent Neutralization by a Low-Affinity Antibody

Authors: Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li-Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

PubMed ID: 41355083

Doi: 10.1002/advs.202517192. Online ahead of print.

Products & Services: Protein and Antibody Isolation

Thermodynamic Profiling Reveals DNA Polymerase Template Binding, Substrate Incorporation, and Exonuclease Function

Authors: Yaping Sun, Wu Lin, Kang Fu, Jie Gao, Xianhui Zhao, Yun He, Hui Tian

Journal: International Journal of Molecular Sciences

Doi: doi.org/10.3390/ijms262411909

Products & Services: Gene Synthesis Plasmid DNA Preparation Protein Electrophoresis and Western CRISPR KI Templates

Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity

Authors: Christopher R Horne, Tingting Wang, Samuel N Young, Toby A Dite, Hunter G Nyvall, Sushant Suresh, Katherine A Davies, Abner Gonzalez Castro, Vineet Vaibhav, Lucy J Mather, Laura F Dagley, Matthew J Belousoff, Gerard Manning, Anthony R Means, John E Burke, Janni Petersen, John W Scott, James M Murphy

Journal: The Biochemical journal

PubMed ID: 41003242

Doi: doi.org/10.1042/BCJ20253431

Products & Services: Peptide Synthesis

Iterative Epitope Expansion Enables Structure-Guided de novo Design of IgE-Binding Miniproteins Targeting the FcεRI Interface

Authors: Ido Calman, Hamed Shaykhalishahi, Puwanat Sangkhapreecha, Sharrol Bachas

Journal: biorxiv

Doi: 10.64898/2025.12.27.696647

Products & Services: Protein portfolio