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Amyloidogenic propensity of self-assembling peptides and their adjuvant potential for use as DNA vaccines

Authors: Paresh C Shrimali, Sheng Chen, Anirban Das, Rachel Dreher, Matthew K Howard, Jeremy J Ryan, Jeremy Buck, Darren Kim, Macy L Sprunger, Jai S Rudra, Meredith E Jackrel

Journal: Acta Biomater

PubMed ID: 37586449

Doi: 10.1016/j.actbio.2023.08.015

Products & Services: Protein and Antibody Isolation

Photoexcited cryptochromes interact with ADA2b and SMC5 to promote the repair of DNA double-strand breaks in Arabidopsis

Authors: Tongtong Guo, Minqing Liu, Li Chen, Yao Liu, Ling Li, Yupeng Li, Xiaoli Cao, Zhilei Mao, Wenxiu Wang, Hong-Quan Yang

Journal: Nat Plants

PubMed ID: 37488265

Doi: 10.1038/s41477-023-01461-6

Products & Services: Protein and Antibody Isolation

Brain-Derived 11S Regulator (PA28αβ) Promotes Proteasomal Hydrolysis of Elongated Oligoglutamine-Containing Peptides

Authors: Viacheslav A Kriachkov, Natalia N Gotmanova, Vadim N Tashlitsky, Anna V Bacheva

Journal: Int J Mol Sci

PubMed ID: 37686081

Doi: 10.3390/ijms241713275

Products & Services: Peptide Synthesis

Interference of a mammalian circRNA regulates lipid metabolism reprogramming by targeting miR‑24‑3p/Igf2/PI3K‑AKT‑mTOR and Igf2bp2/Ucp1 axis

Authors: Jiahao Shao , Meigui Wang , Anjing Zhang , Zheliang Liu , Genglong Jiang , Tao Tang , Jie Wang , Xianbo Jia , Songjia Lai

Journal: Cell Mol Life Sci .

PubMed ID: 37587272

Doi: 10.1007/s00018-023-04899-1

Products & Services: Protein Electrophoresis and Western

A systematic safety pipeline for selection of T-cell receptors to enter clinical use

Authors: Zsofia Foldvari , Cathrine Knetter , Weiwen Yang , Thea Johanne Gjerdingen , Ravi Chand Bollineni , Trung The Tran , Fridtjof Lund-Johansen , Arne Kolstad , Kimberley Drousch , Robert Klopfleisch , Matthias Leisegang , Johanna Olweus

Journal: NPJ Vaccines .

PubMed ID: 37607971

Doi: 10.1038/s41541-023-00713-y

Products & Services: Peptide Synthesis

Strand-preferred base editing of organellar and nuclear genomes using CyDENT

Authors: Jiacheng Hu , Yu Sun , Boshu Li , Zhen Liu , Zhiwei Wang , Qiang Gao , Mengyue Guo , Guanwen Liu , Kevin Tianmeng Zhao , Caixia Gao

Journal: Nat Biotechnol .

PubMed ID: 37640945

Doi: 10.1038/s41587-023-01910-9

Products & Services: Gene Synthesis

Rapid and Sensitive Diagnosis of Leber Hereditary Optic Neuropathy Variants Using CRISPR/Cas12a Detection

Authors: Xiaoling Wan, Jieqiong Chen, Yidong Wu, Zhixuan Chen, Yin Liu, Tong Li, Junran Sun, Ting Zhang, Fuling Zhou, Xingxu Huang, Yang Li, Xinjie Wang, Xiaodong Sun

Journal: J Mol Diagn

PubMed ID: 37517824

Doi: 10.1016/j.jmoldx.2023.04.006

Products & Services: Custom DNA/RNA Oligos

Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif

Authors: Peter Schofield, Alexander I Taylor, Jérôme Rihon, Cristian D Peña Martinez, Sacha Zinn, Charles-Alexandre Mattelaer, Jennifer Jackson, Gurpreet Dhaliwal, Guy Schepers, Piet Herdewijn, Eveline Lescrinier, Daniel Christ, Philipp Holliger

Journal: Nucleic Acids Res

PubMed ID: 37439359

Doi: 10.1093/nar/gkad592

Products & Services: Gene Synthesis

Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells

Authors: Kevin M Rattigan, Zuzana Brabcova, Daniele Sarnello, Martha M Zarou, Kiron Roy, Ryan Kwan, Lucie de Beauchamp, Amy Dawson, Angela Ianniciello, Ahmed Khalaf, Eric R Kalkman, Mary T Scott, Karen Dunn, David Sumpton, Alison M Michie, Mhairi Copland, Saverio Tardito, Eyal Gottlieb, G Vignir Helgason

Journal: Nat Commun

PubMed ID: 37591854

Doi: 10.1038/s41467-023-40222-z

Products & Services: Custom DNA/RNA Oligos

Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily

Authors: Fenglian Liu, Yu Dang, Lu Li, Hao Feng, Jianlin Li, Haowei Wang, Xu Zhang, Zhe Zhang, Sheng Ye, Yutao Tian, Qingfeng Chen

Journal: Nat Chem Biol

PubMed ID: 37550431

Doi: 10.1038/s41589-023-01401-7

Products & Services: Peptide Synthesis