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Sarkosyl differentially solubilizes patient-derived alpha-synuclein fibril strains

Authors: Hjalte Gram, Vasileios Theologidis, Thomas Boesen, Poul Henning Jensen

Journal: Front Mol Biosci

PubMed ID: 37621995

Doi: 10.3389/fmolb.2023.1177556

Products & Services: Polyclonal Antibody Services

Rapid and Sensitive Diagnosis of Leber Hereditary Optic Neuropathy Variants Using CRISPR/Cas12a Detection

Authors: Xiaoling Wan, Jieqiong Chen, Yidong Wu, Zhixuan Chen, Yin Liu, Tong Li, Junran Sun, Ting Zhang, Fuling Zhou, Xingxu Huang, Yang Li, Xinjie Wang, Xiaodong Sun

Journal: J Mol Diagn

PubMed ID: 37517824

Doi: 10.1016/j.jmoldx.2023.04.006

Products & Services: Custom DNA/RNA Oligos

Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif

Authors: Peter Schofield, Alexander I Taylor, Jérôme Rihon, Cristian D Peña Martinez, Sacha Zinn, Charles-Alexandre Mattelaer, Jennifer Jackson, Gurpreet Dhaliwal, Guy Schepers, Piet Herdewijn, Eveline Lescrinier, Daniel Christ, Philipp Holliger

Journal: Nucleic Acids Res

PubMed ID: 37439359

Doi: 10.1093/nar/gkad592

Products & Services: Gene Synthesis

Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells

Authors: Kevin M Rattigan, Zuzana Brabcova, Daniele Sarnello, Martha M Zarou, Kiron Roy, Ryan Kwan, Lucie de Beauchamp, Amy Dawson, Angela Ianniciello, Ahmed Khalaf, Eric R Kalkman, Mary T Scott, Karen Dunn, David Sumpton, Alison M Michie, Mhairi Copland, Saverio Tardito, Eyal Gottlieb, G Vignir Helgason

Journal: Nat Commun

PubMed ID: 37591854

Doi: 10.1038/s41467-023-40222-z

Products & Services: Custom DNA/RNA Oligos

Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily

Authors: Fenglian Liu, Yu Dang, Lu Li, Hao Feng, Jianlin Li, Haowei Wang, Xu Zhang, Zhe Zhang, Sheng Ye, Yutao Tian, Qingfeng Chen

Journal: Nat Chem Biol

PubMed ID: 37550431

Doi: 10.1038/s41589-023-01401-7

Products & Services: Peptide Synthesis

Immunogenicity of Mix-and-Match CoronaVac/BNT162b2 Regimen versus Homologous CoronaVac/CoronaVac Vaccination: A Single-Blinded, Randomized, Parallel Group Superiority Trial

Authors: Samar Samoud, Jihene Bettaieb, Mariem Gdoura, Ghassen Kharroubi, Feriel Ben Ghachem, Imen Zamali, Ahlem Ben Hmid, Sadok Salem, Ahmed Adel Gereisha, Mongi Dellagi, Nahed Hogga, Adel Gharbi, Amor Baccouche, Manel Gharbi, Chadha Khemissi, Ghada Akili, Wissem Slama, Nabila Chaieb, Yousr Galai, Hechmi Louzir, Henda Triki, Melika Ben Ahmed

Journal: Vaccines (Basel)

PubMed ID: 37631897

Doi: 10.3390/vaccines11081329

Products & Services: Monoclonal Antibody Services

Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain

Authors: Gabriella O Estevam, Edmond M Linossi, Christian B Macdonald, Carla A Espinoza, Jennifer M Michaud, Willow Coyote-Maestas, Eric A Collisson, Natalia Jura, James S Fraser

Journal: biorxiv

PubMed ID: 37577651

Doi: 10.1101/2023.08.03.551866

Products & Services: Protein and Antibody Isolation

Immune memory shapes human polyclonal antibody responses to H2N2 vaccination

Authors: Yuhe R Yang, Julianna Han, Hailee R Perrett, Sara T Richey, Abigail M Jackson, Alesandra J Rodriguez, Rebecca A Gillespie, Sarah O'Connell, Julie E Raab, Lauren Y Cominsky, Ankita Chopde, Masaru Kanekiyo, Katherine V Houser, Grace L Chen, Adrian B McDermott, Sarah F Andrews, Andrew B Ward

Journal: biorxiv

PubMed ID: 37781590

Doi: 10.1101/2023.08.23.554525

Products & Services: Molecular Biology Reagents

Intracerebral Hemorrhage-Induced Brain Injury: the Role of Lysosomal-Associated Transmembrane Protein 5

Authors: Wei Hua, Shuainan Ma, Yuxin Pang, Qi Liu, Yueying Wang, Zhiyi Liu, Nan Zhao, Naixin Ren, Sinan Jin, Benshuai Wang, Yuejia Song, Jiping Qi

Journal: Mol Neurobiol

PubMed ID: 37525083

Doi: 10.1007/s12035-023-03484-8

Products & Services: Molecular Biology Reagents

Targeted large fragment deletion in plants using paired crRNAs with type I CRISPR system

Authors: Yingnan Li, Boyu Huang, Jian Chen, Liangliang Huang, Jianghai Xu, Yingying Wang, Guanghui Cui, Haiming Zhao, Beibei Xin, Weibin Song, Jian-Kang Zhu, Jinsheng Lai

Journal: Plant Biotechnol J

PubMed ID: 37641539

Doi: 10.1111/pbi.14122

Products & Services: Protein and Antibody Isolation