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Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome

Authors: Hugh D. Goold, Heinrich Kroukamp, Paige E. Erpf, Yu Zhao, Philip Kelso, Julie Calame, John J. B. Timmins, Elizabeth L. I. Wightman, Kai Peng, Alexander C. Carpenter, Briardo Llorente, Carmen Hawthorne, Samuel Clay, Niël van Wyk, Elizabeth L. Daniel, Fergus Harrison, Felix Meier, Robert D. Willows, Yizhi Cai, Roy S. K. Walker, Xin Xu, Monica I. Espinosa, Giovanni Stracquadanio, Joel S. Bader, …Isak S. Pretorius

Journal: Nature Communications

PubMed ID: 39833175

Doi: 10.1038/s41467-024-55318-3

Products & Services: Gene Synthesis

Chemical tools to define and manipulate interferon-inducible Ubl protease USP18

Authors: Griffin J. Davis, Anthony O. Omole, Yejin Jung, Wioletta Rut, Ronald Holewinski, Kiall F. Suazo, Hong-Rae Kim, Mo Yang, Thorkell Andresson, Marcin Drag & Euna Yoo

Journal: Nature Communications

PubMed ID: 39843430

Doi: 10.1038/s41467-025-56336-5

Products & Services: Plasmid DNA Preparation

Nuclear Condensates of WW Domain-Containing Adaptor With Coiled-Coil Regulate Mitophagy via Alternative Splicing

Authors: Jiahe Wang, Yi Fan, Guowen Luo, Liang Xiong, Lijie Wang, Zhuoxuan Wu, Jiayi Wang, Zhengying Peng, Clifford J Rosen, Kefeng Lu, Junjun Jing, Quan Yuan, Zhenwei Zhang, Chenchen Zhou

Journal: Advanced Science

PubMed ID: 39840526

Doi: 10.1002/advs.202406759

Products & Services: Protein and Antibody Isolation

Steric confinement-induced emission probe for monitoring protein conformations in live cells

Authors: Huixia Jia; Lin Yang; Yu Yang; He Liu; Jia Liu; Chunfeng Shang; Zengru Di; Benzhao He; Ke Zhang

Journal: Communications Chemistry

PubMed ID: 41611810

Doi: 10.1038/s42004-026-01914-x

Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer

Authors: Ryan Blawski; Bujamin H. Vokshi; Xinyu Guo; Srushti Kittane; Mirna Sallaku; Wanlu Chen; Martina Gjyzari; Tony Cheung; Yuhan Zhang; Christopher Simpkins; Weiqiang Zhou; Amanda Kulick; Peihua Zhao; Meihan Wei; Pranavkrishna Shivashankar; Tatiana Prioleau; Pedram Razavi; Richard Koche; Vito W. Rebecca; Elisa de Stanchina; Pau Castel; Ho Man Chan; Maurizio Scaltriti; Emiliano Cocco; Hongkai Ji; Minkui Luo; Eneda Toska

Journal: Cell Reports

PubMed ID: 38700982

Doi: 10.1016/j.celrep.2024.114174

Products & Services: Peptide Synthesis

Deep mutational scanning and machine learning for the analysis of antimicrobial-peptide features driving membrane selectivity

Authors: Justin R. Randall; Luiz C. Vieira; Claus O. Wilke; Bryan W. Davies

Journal: Nature biomedical engineering

PubMed ID: 39085646

Doi: 10.1038/s41551-024-01243-1

Products & Services: Peptide Synthesis

Dictating the spatial-temporal delivery of molecular adjuvant and antigen for the enhanced vaccination

Authors: Yumeng Yan , Xiaonan Huang , Lili Yuan , To Ngai , Guanghui Ma , Yufei Xia

Journal: Biomaterials

PubMed ID: 38968687

Doi: 10.1016/j.biomaterials.2024.122697

Products & Services: Peptide Synthesis

Engineered Magneto-Piezoelectric Nanoparticles-Enhanced Scaffolds Disrupt Biofilms and Activate Oxidative Phosphorylation in Icam1+ Macrophages for Infectious Bone Defect Regeneration

Authors: Hao Wu , Changcheng Chen , Jiangfeng Li , Dongmei Yu , Xun Wu , Hai Huang , Zhen Tang , Qi Wu , Shichao Yan , Ning Wang , Mo Wang , Feilong Wei , Yunlong Yu , Duan Wang , Mengting Shi , Xusong Yue , Pengfei Cao , Zenghui Zheng , Xiaokang Li , Baolin Guo , Lei Shi , Zheng Guo

Journal: ACS Nano

PubMed ID: 39690461

Doi: 10.1021/acsnano.4c13562

Products & Services: Protein Electrophoresis and Western

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Authors: Marcell Crispim; Ignasi Bofill Verdaguer; Agust n Hern ndez; Thales Kronenberger; ngel Fenollar; Lydia Fumiko Yamaguchi; Mar a P a Alberione; Miriam Ramirez; Sandra Souza de Oliveira; Alejandro Miguel Katzin; Luis Izquierdo; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning