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页码: 156/5356 每页显示数量

A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing

Authors: Yongliang Tong , Runqiu Chen , Xinrong Lu , Cuiying Chen , Guiqin Sun , Xiaolu Yu , Shaoxian Lyu , Meiqing Feng , Yiru Long , Likun Gong , Li Chen

Journal: Int J Biol Macromol

PubMed ID: 39824395

Doi: 10.1016/j.ijbiomac.2025.139953

Products & Services: Gene Synthesis

Restoring tumor antigenicity activates the “bystander” T cell immune cycle

Authors: Yifan Yang , Qiumin Yu , Haoyu Zhang , Yuchen Liu , Hexuan Wang , Ningyi Yang , Yulian Shi , Wanli Zhang , Zijie Wu , Shitong Huang , Wenbin Xie , Ran Duan , Qiuli Mao , Xupeiyao Shi , Zheng Gao , Xiaoning Wang , Hanlin Guo , Lingxiao Chen , Yi Han , Ximing Li , Liyuan Chen , Siqi Tang , Ying Fan , Wenbing Yao , Hong Tian , Xiangdong Gao

Journal: J Control Release

PubMed ID: 39894265

Doi: 10.1016/j.jconrel.2025.01.094

Products & Services: Gene Synthesis

Manganese Galvanic Cells Intervene in Tumor Metabolism to Reinforce cGAS-STING Activation for Bidirectional Synergistic Hydrogen-Immunotherapy

Authors: Nailin Yang , Shumin Sun , Jiachen Xu , Fei Gong, Huali Lei , Yu Hao , Zifan Pei , Chenya Wang , Qiao Yu , Jihu Nie , Nan Jiang , Caifang Ni , Liang Cheng

Journal: Adv Mater

PubMed ID: 10.1002/adma.202414929

Doi: 10.1002/adma.202414929

Products & Services: Protein and Antibody Isolation

Computational design, expression, and characterization of a Plasmodium falciparum multi-epitope, multi-stage vaccine candidate (PfCTMAG)

Authors: Joan A Chick, Nadege N Abongdia, Robert A Shey, Tobias O Apinjoh

Journal: Heliyon

PubMed ID: 39906795

Doi: 10.1016/j.heliyon.2025.e42014

Products & Services: Bacterial Expression

TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy

Authors: Chunyang Cai, Chufeng Gu, Shuai He, Chunren Meng, Dongwei Lai, Jingfa Zhang, Qinghua Qiu

Journal: Clinical epigenetics

PubMed ID: 38172938

Doi: 10.1186/s13148-023-01619-1

Products & Services: Protein and Antibody Isolation

Steric confinement-induced emission probe for monitoring protein conformations in live cells

Authors: Huixia Jia; Lin Yang; Yu Yang; He Liu; Jia Liu; Chunfeng Shang; Zengru Di; Benzhao He; Ke Zhang

Journal: Communications Chemistry

PubMed ID: 41611810

Doi: 10.1038/s42004-026-01914-x

Steric confinement-induced emission probe for monitoring protein conformations in live cells

Authors: Huixia Jia; Lin Yang; Yu Yang; He Liu; Jia Liu; Chunfeng Shang; Zengru Di; Benzhao He; Ke Zhang

Journal: Communications Chemistry

PubMed ID: 41611810

Doi: 10.1038/s42004-026-01914-x

Steric confinement-induced emission probe for monitoring protein conformations in live cells

Authors: Huixia Jia; Lin Yang; Yu Yang; He Liu; Jia Liu; Chunfeng Shang; Zengru Di; Benzhao He; Ke Zhang

Journal: Communications Chemistry

PubMed ID: 41611810

Doi: 10.1038/s42004-026-01914-x

Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer

Authors: Ryan Blawski; Bujamin H. Vokshi; Xinyu Guo; Srushti Kittane; Mirna Sallaku; Wanlu Chen; Martina Gjyzari; Tony Cheung; Yuhan Zhang; Christopher Simpkins; Weiqiang Zhou; Amanda Kulick; Peihua Zhao; Meihan Wei; Pranavkrishna Shivashankar; Tatiana Prioleau; Pedram Razavi; Richard Koche; Vito W. Rebecca; Elisa de Stanchina; Pau Castel; Ho Man Chan; Maurizio Scaltriti; Emiliano Cocco; Hongkai Ji; Minkui Luo; Eneda Toska

Journal: Cell Reports

PubMed ID: 38700982

Doi: 10.1016/j.celrep.2024.114174

Products & Services: Peptide Synthesis

Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome

Authors: Hugh D. Goold, Heinrich Kroukamp, Paige E. Erpf, Yu Zhao, Philip Kelso, Julie Calame, John J. B. Timmins, Elizabeth L. I. Wightman, Kai Peng, Alexander C. Carpenter, Briardo Llorente, Carmen Hawthorne, Samuel Clay, Niël van Wyk, Elizabeth L. Daniel, Fergus Harrison, Felix Meier, Robert D. Willows, Yizhi Cai, Roy S. K. Walker, Xin Xu, Monica I. Espinosa, Giovanni Stracquadanio, Joel S. Bader, …Isak S. Pretorius

Journal: Nature Communications

PubMed ID: 39833175

Doi: 10.1038/s41467-024-55318-3

Products & Services: Gene Synthesis