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页码: 151/5153 每页显示数量

AIRE is expressed in breast cancer TANs and TAMs to regulate the extrinsic apoptotic pathway and inflammation

Authors: Eva Källberg, Meliha Mehmeti-Ajradini, Frida Björk Gunnarsdottir, Marcus Göransson, Caroline Bergenfelz, Roni Allaoui Fredriksson, Catharina Hagerling, Martin E Johansson, Charlotte Welinder, Karin Jirström, Karin Leandersson

Journal: J Leukoc Biol

PubMed ID: 38060995

Doi: 10.1093/jleuko/qiad152

Products & Services: Custom Vector Construction

IgG hexamers initiate complement-dependent acute lung injury

Authors: Simon J Cleary, Yurim Seo, Jennifer J Tian, Nicholas Kwaan, David P Bulkley, Arthur Eh Bentlage, Gestur Vidarsson, Éric Boilard, Rolf Spirig, James C Zimring, Mark R Looney

Journal: J Clin Invest

PubMed ID: 38530369

Doi: 10.1172/JCI178351

Products & Services: Protein and Antibody Isolation

The replication phenotype of hepatitis B virus (HBV) splice variants Sp3 and Sp9 and their impact on wild-type HBV replication

Authors: Laura C McCoullough, Tomas Sadauskas, Vitina Sozzi, Kai Yan Mak, Hugh Mason, Margaret Littlejohn, Peter A Revill

Journal: J Virol

PubMed ID: 38501924

Doi: 10.1128/jvi.01538-23

Products & Services: Protein and Antibody Isolation

A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results

Authors: Amy R Rappaport, Chrisann Kyi, Monica Lane, Meghan G Hart, Melissa L Johnson, Brian S Henick, Chih-Yi Liao, Amit Mahipal, Ardaman Shergill, Alexander I Spira, Jonathan W Goldman, Ciaran D Scallan, Desiree Schenk, Christine D Palmer, Matthew J Davis, Sonia Kounlavouth, Lindsey Kemp, Aaron Yang, Yaojun John Li, Molly Likes, Annie Shen, Gregory R Boucher, Milana Egorova, Robert L Veres, J Aaron Espinosa, Jason R Jaroslavsky, Lauren D Kraemer Tardif, Lindsey Acrebuche, Christopher Puccia, Leiliane Sousa, Rita Zhou, Kyounghwa Bae, J Randolph Hecht, David P Carbone, Benny Johnson, Andrew Allen, Andrew R Ferguson, Karin Jooss

Journal: Nat Med

PubMed ID: 38538867

Doi: 10.1038/s41591-024-02851-9

Products & Services: Molecular Biology Reagents

Biochemical and structural analysis of N-myristoyltransferase mediated protein tagging

Authors: Paul Monassa , Frédéric Rivière , Cyril Dian , Frédéric Frottin , Carmela Giglione , Thierry Meinnel

Journal: Methods Enzymol .

PubMed ID: 37230587

Doi: 10.1016/bs.mie.2023.02.016

Products & Services: Peptide Synthesis

Kinetic and catalytic features of N-myristoyltransferases

Authors: Frédéric Rivière , Paul Monassa , Carmela Giglione , Thierry Meinnel

Journal: Methods Enzymol .

PubMed ID: 37230588

Doi: 10.1016/bs.mie.2023.02.018

Products & Services: Peptide Synthesis

A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins

Authors: Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters

Journal: Nature

PubMed ID: 38509117

Doi: 10.1038/s41467-024-46644-7

Products & Services: Plasmid DNA Preparation

Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology

Authors: Brendan Miller, Su-Jeong Kim, Kevin Cao, Hemal H Mehta, Neehar Thumaty, Hiroshi Kumagai, Tomomitsu Iida, Cassandra McGill, Christian J Pike, Kamila Nurmakova, Zachary A Levine, Patrick M Sullivan, Kelvin Yen, Nilüfer Ertekin-Taner, Gil Atzmon, Nir Barzilai, Pinchas Cohen

Journal: Cell

PubMed ID: 38520065

Doi: 10.1111/acel.14153

Products & Services: Gene Synthesis

ARGLU1 enhances promoter-proximal pausing of RNA polymerase II and stimulates DNA damage repair

Authors: Scott Bachus, Nikolas Akkerman, Lauren Fulham, Drayson Graves, Rafe Helwer, Jordan Rempel, Peter Pelka

Journal: Nucleic Acids Research

PubMed ID: 38520408

Doi: 10.1093/nar/gkae208

Products & Services: Gene Synthesis

DNA fragility at topologically associated domain boundaries is promoted by alternative DNA secondary structure and topoisomerase II activity

Authors: Heather M Raimer Young, Pei-Chi Hou, Anna R Bartosik, Naomi D Atkin, Lixin Wang, Zhenjia Wang, Aakrosh Ratan, Chongzhi Zang, Yuh-Hwa Wang

Journal: Nucleic Acids Research

PubMed ID: 38452213

Doi: 10.1093/nar/gkae164

Products & Services: Gene Synthesis