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页码: 129/5357 每页显示数量

Discovery of diverse and high-quality mRNA capping enzymes through a language model–enabled platform

Authors: Tianze Wang, Bowen R Qin, Sihong Li, Zimo Wang, Xuejian Li, Yuanxu Jiang, Chenrui Qin, Qi Ouyang, Chunbo Lou, Long Qian

Journal: SCIENCE ADVANCES

PubMed ID: 40203090

Doi: 10.1126/sciadv.adt0402

Products & Services: Gene Synthesis

Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair

Authors: Marianna Genta, Giulia Ferrara, Riccardo Capelli, Diego Rondelli, Sarah Sertic, Martino Bolognesi, Menico Rizzi, Franca Rossi, David Jeruzalmi, Antonio Chaves-Sanjuan & Riccardo Miggiano

Journal: Nature Communications

PubMed ID: 40210888

Doi: 10.1038/s41467-025-58670-0

Products & Services: Gene Synthesis

Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates

Authors: Nadia A. Erkamp, Mina Farag, Yuanxin Qiu, Daoyuan Qian, Tomas Sneideris, Tingting Wu, Timothy J. Welsh, Hannes Ausserwöger, Tommy J. Krug, Gaurav Chauhan, David A. Weitz, Matthew D. Lew, Tuomas P. J. Knowles & Rohit V. Pappu

Journal: Nature Communications

PubMed ID: 40216775

Doi: 10.1038/s41467-025-58736-z

Controlled and orthogonal partitioning of large particles into biomolecular condensates

Authors: Fleurie M. Kelley, Anas Ani, Emily G. Pinlac, Bridget Linders, Bruna Favetta, Mayur Barai, Yuchen Ma, Arjun Singh, Gregory L. Dignon, Yuwei Gu & Benjamin S. Schuster

Journal: Nature Communications

PubMed ID: 40229261

Doi: 10.1038/s41467-025-58900-5

Products & Services: Custom Vector Construction

Molecular basis of human GABA transporter 3 inhibition

Authors: Ravi Yadav, Gye Won Han, Cornelius Gati

Journal: Nature Communications

PubMed ID: 40268946

Doi: 10.1038/s41467-025-59066-w

Products & Services: Gene Synthesis

Zonated Copper-Driven Breast Cancer Progression Countered by a Copper-Depleting Nanoagent for Immune and Metabolic Reprogramming

Authors: Lin Chen, Saibo Ma, Hao Wu, Lingna Zheng, Yunpeng Yi, Guangnian Liu, Baoyi Li, Jiayi Sun, Yang Du, Bing Wang, Yike Liu, Cheng Zhang, Jing Chang, Yuheng Pang, Wenjing Wang, Meng Wang, Motao Zhu

Journal: Advanced Science

PubMed ID: 40270472

Doi: 10.1002/advs.202412434

Products & Services: Recombinant Proteins

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

Authors: Chunlong Ma; Michael Dominic Sacco; Zilei Xia; George Lambrinidis; Julia Alma Townsend; Yanmei Hu; Xiangzhi Meng; Tommy Szeto; Mandy Ba; Xiujun Zhang; Maura Gongora; Fushun Zhang; Michael Thomas Marty; Yan Xiang; Antonios Kolocouris; Yu Chen; Jun Wang

Journal: ACS central science

PubMed ID: 34341772

Doi: 10.1021/acscentsci.1c00519

Virus glycoprotein nanodisc platform for vaccine design

Authors: Kimmo Rantalainen; Alessia Liguori; Gabriel Ozorowski; Claudia Flynn; Jon M. Steichen; Olivia Swanson; Patrick J. Madden; Sabyasachi Baboo; Swastik Phulera; Anant Gharpure; Danny Lu; Oleksandr Kalyuzhniy; Patrick Skog; Sierra Terada; Monolina Shil; Jolene K. Diedrich; Erik Georgeson; Ryan Tingle; Saman Eskandarzadeh; Wen-Hsin Lee; Nushin Alavi; Diana Goodwin; Michael Kubitz; Sonya Amirzehni; Sunny Himansu; Devin Sok; Jeong Hyun Lee; John R. Yates; James C. Paulson; Shane Crotty; Torben Schiffner; Andrew B. Ward; William R. Schief

Journal: biorxiv

PubMed ID: 40666859

Doi: 10.1101/2025.05.02.651272

Products & Services: Catalog Antibodies

Virus glycoprotein nanodisc platform for vaccine design

Journal: biorxiv

PubMed ID: 40666859

Doi: 10.1101/2025.05.02.651272

Products & Services: Catalog Antibodies

Targeting the Fusion Process of SARS-CoV-2 Infection by Small Molecule Inhibitors

Authors: Seung Bum Park; Parker Irvin; Zongyi Hu; Mohsin Khan; Xin Hu; Qiru Zeng; Catherine Chen; Miao Xu; Madeleine Leek; Ruochen Zang; James Brett Case; Wei Zheng; Siyuan Ding; T. Jake Liang

Journal: MBio

PubMed ID: 35012356

Doi: 10.1128/mbio.03238-21