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Doublecortin restricts neuronal branching by regulating tubulin polyglutamylation

Authors: Muriel Sébastien, Alexandra L Paquette, Emily N P Prowse, Adam G Hendricks, Gary J Brouhard

Journal: Nature Communications

PubMed ID: 39966472

Doi: 10.1038/s41467-025-56951-2

Products & Services: Protein Electrophoresis and Western

Non-AUG HIV-1 uORF translation elicits specific T cell immune response and regulates viral transcript expression

Authors: Emmanuel Labaronne, Didier Décimo, Lisa Bertrand, Laura Guiguettaz, Thibault J M Sohier, David Cluet, Valérie Vivet-Boudou, Ana Luiza Chaves Valadão, Clara Dahoui, Pauline François, Isabelle Hatin, Olivier Lambotte, Assia Samri, Brigitte Autran, Lucie Etienne, Caroline Goujon, Jean-Christophe Paillart, Olivier Namy, Bertha Cecilia Ramirez, Théophile Ohlmann, Arnaud Moris, Emiliano P Ricci

Journal: Nature Communications

PubMed ID: 39966383

Doi: 10.1038/s41467-025-56772-3

Products & Services: Peptide Synthesis

LCK-co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity

Authors: Justin B Zhang, Priyanka Chaurasia, Angela Nguyen, Zijian Huang, Trang T Nguyen, Hui Xu, Mai T Tran, Hugh H Reid, Claerwen M Jones, Stefan A Schattgen, Daniel Thiele, Paul G Thomas, Jeanette Rientjes, Kim L Good-Jacobson, Roland Ruscher, Dene R Littler, Jamie Rossjohn, Pirooz Zareie, Nicole L La Gruta

Journal: Science immunology

PubMed ID: 39982976

Doi: 10.1126/sciimmunol.adp5016

Products & Services: Custom Vector Construction

A rational multi-target combination strategy for synergistic improvement of non-ribosomal peptide production

Authors: Hao Yan, Zhenguo Xin, Ziwei Sang, Xingwang Li, Jia Xie, Jiale Wu, Shen Pang, Ying Wen, Weishan Wang

Journal: Nature Communications

PubMed ID: 39987186

Doi: 10.1038/s41467-025-57073-5

Products & Services: Gene Synthesis

Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

Authors: Feifei Yuan, Jihong Yang, Fanglin Ma, Zhe Hu, Vikas Malik, Ruge Zang, Dan Li, Xianle Shi, Xin Huang, Hongwei Zhou, Jianlong Wang

Journal: Nature Communications

PubMed ID: 39988597

Doi: 10.1038/s41467-025-57165-2

Products & Services: Protein Electrophoresis and Western

The structure of FCGBP is formed as a disulfide‐mediated homodimer between its C‐terminal domains

Authors: Erik Ehrencrona, Pablo Gallego, Sergio Trillo-Muyo, Maria-Jose Garcia-Bonete, Christian V Recktenwald, Gunnar C Hansson, Malin E V Johansson

Journal: FEBS Journal

PubMed ID: 39754272

Doi: 10.1111/febs.17383

Products & Services: Gene Synthesis

Perturbing Organelle-Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion-Mediated Cancer Immunotherapy

Authors: Jun-Long Liang , Qian-Xiao Huang , Qi-Wen Chen , Xiao-Kang Jin , Zi-Yi Han 1, Ping Ji , Si-Xue Cheng , Wei-Hai Chen , Xian-Zheng Zhang

Journal: Adv Mater

PubMed ID: 39955648

Doi: 10.1002/adma.202416574

Products & Services: Recombinant Proteins

Elastin-like polypeptide: A novel titanification biomacromolecule for green and ultrafast synthesis of biotitania nanoparticles via biomimetic mineralization

Authors: Lixi Cai, Jinlin Zheng, Lixing Liu, Guangya Zhang, Yuanqing Lin

Journal: Int J Biol Macromol

PubMed ID: 40015400

Doi: 10.1016/j.ijbiomac.2025.141449

Products & Services: Gene Synthesis

A Granzyme B‑Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes

Authors: Yanfang Wang, Yanping Sun, Xiuwen Zhang, Shenqiang Wang, Xuehui Huang, Kairui Xu, Yun Liu, Yingqi Huang, Jianchang Xu, Xinwei Wei, Hao Cheng, Liqiang Pan, Jinqiang Wang, Zhen Gu

Journal: Journal of the American Chemical Society

PubMed ID: 39869523

Doi: 10.1021/jacs.4c13644

Products & Services: Gene Synthesis

Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival

Authors: Wen Wei, Xueqin Gao, Jiawei Qian, Lei Li, Chen Zhao, Li Xu, Yanfei Zhu, Zhenzhen Liu, Nengrong Liu, Xueqing Wang, Zhicong Jin, Bowen Liu, Lan Xu, Jin Dong, Suping Zhang, Jiarong Wang, Yumu Zhang, Yao Yu, Zhanjun Yan, Yanjun Yang, Jie Lu, Yixuan Fang, Na Yuan, Jianrong Wang

Journal: Journal of Clinical Investigation

PubMed ID: 39589832

Doi: 10.1172/JCI177375.

Products & Services: Protein and Antibody Isolation