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Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I
Authors: Bryan Neumann, Stephen McCarthy, Shane Gonen
Journal: Nature Communications
PubMed ID: 39920100
Doi: 10.1038/s41467-024-55764-z
Products & Services: Codon Optimization   
Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism
Authors: Laleh Khodaparast, Ladan Khodaparast, Ramon Duran-Romaña, Guiqin Wu, Bert Houben, Wouter Duverger, Matthias De Vleeschouwer, Katerina Konstantoulea, Fleur Nysen, Thomas Schalck, Daniel J Curwen, Lisandra L Martin, Sebastien Carpentier, Bernard Scorneaux, Jan Michiels, Joost Schymkowitz, Frederic Rousseau
Journal: Nature Communications
PubMed ID: 39939597
Doi: 10.1038/s41467-025-56873-z
Products & Services: Peptide Synthesis   
Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers
Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li
Journal: Nature Communications
PubMed ID: 39952937
Doi: 10.1038/s41467-025-56407-7
Products & Services: Recombinant Proteins   
Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense
Authors: Hana Zand Karimi, Kuo-En Chen, Marilee Karinshak, Xilin Gu, Jason K Sello, Richard D Vierstra
Journal: Nature Communications
PubMed ID: 39952938
Doi: 10.1038/s41467-025-56594-3
Products & Services: Peptide Synthesis   
GMRSP encoded by lncRNA H19 regulates metabolic reprogramming and alleviates aortic dissection
Authors: Jizhong Wang, Jitao Liu, Fan Yang, Yinghao Sun, Jiaohua Chen, Jie Liu, Tucheng Sun, Ruixin Fan, Fang Pei, Songyuan Luo, Jie Li, Jianfang Luo
Journal: Nature Communications
PubMed ID: 39966416
Doi: 10.1038/s41467-025-57011-5
Alternatively spliced NFKB1 transcripts enriched in Andean Aymara modulate inflammation, HIF and hemoglobin
Authors: Jihyun Song, Seonggyun Han, Ricardo Amaru, Lucie Lanikova, Teddy Quispe, Dongwook Kim, Jacob E Crawford, Soo Jin Kim, Younghee Lee, Josef T Prchal
Journal: Nature Communications
PubMed ID: 39971917
Doi: 10.1038/s41467-025-56848-0
Products & Services: Protein Electrophoresis and Western   
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.
Authors: Qiyu Tang, Keyi Tang, Greg R Markby, Maciej Parys, Kanchan Phadwal, Vicky E MacRae, Brendan M Corcoran
Journal: Autophagy
PubMed ID: 39988732
Doi: 10.1080/15548627.2025.2469315
Products & Services: CRISPR Plasmids   
Pan-Variant SARS-CoV-2 Vaccines Induce Protective Immunity by Targeting Conserved Epitopes
Authors: Masaud Shah, Sung Ung Moon, Ji-Yon Shin, Ji-Hye Choi, Doyoon Kim, Hyun Goo Woo
Journal: Advanced Science
PubMed ID: 40014015
Doi: 10.1002/advs.202409919
Products & Services: Peptide Synthesis   
Sequence Context-Agnostic TadA-Derived Cytosine Base Editors for Genome-Wide Editing in Zebrafish
Authors: Shaohui Zheng 1 2, Yang Liu 1 2, Xinxin Xia 1 2, Jiawang Xiao 1 2, Hui Ma 3, Xuanyao Yuan 1 2, Yan Zhang 1 2, Zixi Chen 1 2, Guangcong Peng 1 2, Wenyuan Li 4, Ji-Feng Fei 3 5 6, Yanmei Liu
Journal: Advanced Science
PubMed ID: 39960330
Doi: 10.1002/advs.202411478
Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1
Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar
Journal: Vaccine
PubMed ID: 39787798
Doi: 10.1016/j.vaccine.2024.126696
Products & Services: Gene Synthesis   Plasmid DNA Preparation   
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