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页码: 8/4912 每页显示数量

Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery

Authors: Liang Leng, Zhichao Xu, Bixia Hong, Binbin Zhao, Ya Tian, Can Wang, Lulu Yang, Zhongmei Zou, Lingyu Li, Ke Liu, Wanjun Peng, Jiangning Liu, Zhoujie An, Yalin Wang, Baozhong Duan, Zhigang Hu, Chuan Zheng, Sanyin Zhang, Xiaodong Li, Maochen Li, Zhaoyu Liu, Zenghao Bi, Tianxing He, Baimei Liu, Huahao Fan, Chi Song, Yigang Tong, Shilin Chen

Journal: Nat Commun .

PubMed ID: 38378731

Doi: 10.1038/s41467-024-45690-5

Products & Services: Catalog Antibody

Insertion of a FLAG-tag sequence at the end of exon 9 of the TBX5 gene in three induced pluripotent stem cell lines (DHMi004-A-4, DHMi004-A-5, DHMi004-A-6) by CRISPR/Cas9 technology

Authors: Harald Lahm, Niraj K Singh, Irina Gottmann, Stefanie A Doppler, Elda Dzilic, Heike Preisler, Stephanie Schneider, Rüdiger Lange, Markus Krane, Martina Dreßen

Journal: Cell Research

PubMed ID: 38100916

Doi: 10.1016/j.scr.2023.103261

Products & Services: Plasmid DNA Preparation

Carotenoid cleavage enzymes evolved convergently to generate the visual chromophore

Authors: Yasmeen J Solano , Michael P Everett , Kelly S Dang , Jude Abueg , Philip D Kiser

Journal: Nature Chemical Biology

PubMed ID: 38355721

Doi: 10.1038/s41589-024-01554-z

Products & Services: Plasmid DNA Preparation

Biomimetic bacteria-derived nanoclusters enhance ferroptosis cancer immunotherapy through synergistic CRISPR-photothermo modulation

Authors: Xiuhua Pan , Jie Yang , Ruixin Kang , Jun Zhang , Zongwei Hu , Ning Yang , Zengyi Liu , Zengguang Jia , Xiawei Zhou , Qi Shen

Journal: Nano Today

Doi: 10.1016/j.nantod.2024.102213

Products & Services: CRISPR Services

Disordered regions mediate the interaction of p53 and MRE11

Authors: Sinem Usluer , Markus Galhuber , Yukti Khanna , Benjamin Bourgeois , Emil Spreitzer , Helene Michenthaler, Andreas Prokesch, Tobias Madl

Journal: Cell Research

PubMed ID: 38123020

Doi: 10.1016/j.bbamcr.2023.119654

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Bile salt hydrolase catalyses formation of amine-conjugated bile acids

Authors: Bipin Rimal, Stephanie L Collins, Ceylan E Tanes, Edson R Rocha, Megan A Granda, Sumeet Solanki, Nushrat J Hoque, Emily C Gentry, Imhoi Koo, Erin R Reilly, Fuhua Hao, Devendra Paudel, Vishal Singh 11, Tingting Yan 12, Min Soo Kim 2, Kyle Bittinger 3, Joseph P Zackular 13 14, Kristopher W Krausz 12, Dhimant Desai 15, Shantu Amin 15, James P Coleman 4, Yatrik M Shah 5, Jordan E Bisanz 2 16, Frank J Gonzalez 12, John P Vanden Heuvel 1 17, Gary D Wu 18, Babette S Zemel 3, Pieter C Dorrestein 7 8, Emily E Weinert 2 6, Andrew D Patterson 19 20 21

Journal: Nature

PubMed ID: 38326609

Doi: 10.1038/s41586-023-06990-w

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Harnessing eukaryotic retroelement proteins for transgene insertion into human safe-harbor loci

Authors: Xiaozhu Zhang, Briana Van Treeck, Connor A. Horton, Jeremy J. R. McIntyre, Sarah M. Palm, Justin L. Shumate & Kathleen Collins

Journal: Nat Biotechnol

PubMed ID: 38379101

Doi: 10.1038/s41587-024-02137-y

Products & Services: Plasmid DNA Preparation

Distinct structural variants and repeat landscape shape the genomes of the ancient grapes Aglianico and Falanghina

Authors: Riccardo Aversano, Marina Iovene , Salvatore Esposito , Alberto L'Abbate , Clizia Villano , Ermanno Di Serio , Maria Francesca Cardone , Carlo Bergamini , Riccardo Aiese Cigliano , Vincenzo D'Amelia , Luigi Frusciante , Domenico Carputo

Journal: BMC Plant Biol.

PubMed ID: 38317087

Doi: 10.1186/s12870-024-04778-2

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Structure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1

Authors: Xiangwei Wu, Yunxiang Du, Lu-Jun Liang, Ruichao Ding, Tianyi Zhang, Hongyi Cai, Xiaolin Tian, Man Pan, Lei Liu

Journal: Nat Commun .

PubMed ID: 38341401

Doi: 10.1038/s41467-024-45635-y

Products & Services: Gene Synthesis

Mage Transposon: A Novel Gene Delivery System for Mammalian Cells

Authors: Jinghan Tian, Doudou Tong, Zhendong Li, Erqiang Wang, Yifei Yu, Hangya Lv, Zhendan Hu, Fang Sun, Guoping Wang, Min He, Tian Xia

Journal: Nucleic Acids Res .

PubMed ID: 38300794

Doi: 10.1093/nar/gkae048

Products & Services: Gene Synthesis

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