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cPLA2α targeting to exosomes connects nuclear deformation to LTB4-signaling during neutrophil chemotaxis

Authors: Subhash B Arya, Fatima Jordan-Javed, Kristen Loesel, Yehyun Choi, Samuel P Collie, Lauren E Hein, Brendon M Baker, Euisik Yoon, Carole A Parent

Journal: SCIENCE ADVANCES

PubMed ID: 41719396

Doi: 10.1126/sciadv.aea2784

Trypanosome histone variants H3.V and H4.V promote nucleosome plasticity in repressed chromatin

Authors: Gauri Deák, Hayden Burdett, James A Watson, Marcus D Wilson

Journal: Molecular Therapy

PubMed ID: 41709455

Doi: 10.1016/j.str.2026.01.008

Products & Services: Codon Optimization

Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer

Authors: Zecheng Yang, Madelaine S Theardy, Shuaitong Chen, Yongkun Wei, Mitsunobu Takeda, Yue Zeng, Xiaofei Wang, Jun Yao, Jennifer Li, Prapassorn Thirasastr, Jangho Park, Yangxi Zheng, Long T Vien, Khalida M Wani, Huamin Wang, Sisi Gao, Tim Heffernan, Lawrence Kwong, Ignacio I Wistuba, Laura Bover, Giulio F Draetta, Haoqiang Ying, Wantong Yao

Journal: Molecular Therapy

PubMed ID: 41707651

Doi: 10.1016/j.xcrm.2026.102613

OsWRKY53-OsGT1 Module Regulates Rice Tiller Development and Is Involved in Fine-Tuning Strigolactone Signaling

Authors: Jiaqi Tang, Guilong Zhao, Jiangli Yang, Zhuo Chen, Zhipeng Hong, Xin Jin, Ziming Qiu, Zhenyu Wang, Xiufeng Li, Jijun Yan, Changhua Liu, Weiqiang Li, Jinfang Chu, Yuanhu Xuan, Xiaojie Tian, Qingyun Bu

Journal: Plant Biotechnology Journal

PubMed ID: 41641886

Doi: 10.1111/pbi.70578

Products & Services: Protein and Antibody Isolation

A tripartite AAV System with Engineered Lox Sites Enables Efficient Delivery of the EYS Gene for Retinal Gene Therapy

Authors: Kun-Do Rhee, Poppy Datta, Clairissa Baccam, Seongjin Seo

Journal: Human gene therapy

PubMed ID: 41714294

Doi: 10.11710430342261426597

Products & Services: PCR Cloning and Subcloning Custom Vector Construction

A novel alphavirus-based saRNA platform for enhanced vaccination efficacy and organ-specific targeting

Authors: Zhen Sun, Yuxiao Liu, Haoyi Zhang, Ting Ge, Yuting Pan, Yang Liu, Miaomiao Wu, Tao Shan, Guoqiang Zhu, Qi Wu, Kangming Chen

Journal: Vaccine

PubMed ID: 41349243

Doi: 10.1016/j.vaccine.2025.128055

Products & Services: Custom mRNA synthesis

Rapid discovery of repurposed drugs targeting SARS-CoV-2 spike HR1 by DNA-encoded library screening

Authors: Qingao Xue, Ze Liang, Yi Zhang, Fei Wang, Fulian Wang, Lili Liu, Guang Yang, Lei Yan

Journal: Bioorganic Chemistry

PubMed ID: 41691755

Doi: 10.1016/j.bioorg.2026.109627

Products & Services: Peptide Synthesis

Ultrafast and Green Encapsulation of Enzymes in Biotitania Nanoparticles via Elastin-like Polypeptide-Mediated Biomimetic Mineralization

Authors: Lin, Yuanqing; He, Yichen; He, Ziyun; Zhan, Weichen; Huang, Yidan; Li, Xue; Cai, Jinzhong; Chen, Lanfang; Xiao, Zushun; Liu, Xingxing; Zhang, Guangya

Journal: ACS Sustainable Chemistry & Engineering

Doi: 10.1021/acssuschemeng.5c12382

Products & Services: Protein Electrophoresis and Western

Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates

Authors: Ignacio Relano-Rodriguez, Jianqiu Du, Zi Jie Lin, Margaret Kerwin, Marta Tarquis-Medina, Eduardo Urbano, Jiayan Cui, Meagan Watkins, Christy L Lavine, Peng Zhao, Rumi Habib, Colby Agostino, Sukanya Ghosh, Joyce Park, Caroline Boroughs, Agnes A Walsh, Mariane B Melo, Niharika Shukla, George M Shaw, Beatrice H Hahn, Darrell J Irvine, Lance Wells, David B Weiner, Michael S Seaman, Daniel W Kulp, Ronald S Veazey, Jesper Pallesen, Amelia Escolano

Journal: nature immunology

PubMed ID: 41634485

Doi: 10.1038/s41590-025-02408-z

Expression of IMD-CBM peptide induces the autophagic degradation of CAV1 (caveolin 1) to inhibit LDL transcytosis and retard diabetic atherosclerosis

Authors: Li Wang, Xiong Jia, Xiangli Bai, Ying Zhao, Wenzhuo Cheng, Meng Shu, Yan Shu, Liyin Zhang, Ruonan Wang, Si Jin

Journal: Autophagy

PubMed ID: 41686177

Doi: 10.1080/15548627.2026.2631946