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Developing deprotectase biocatalysts for synthesis

Authors: Lisa Kennedy, Mariyah Sajjad, Michael A Herrera, Peter Szieber, Natasza Rybacka, Yinan Zhao, Craig Steven, Zainab Alghamdi, Ivan Zlatkov, Julie Hagen, Chloe Lauder, Natalie Rudolfova, Magdalena Abramiuk, Karolina Bolimowska, Daniel Joynt, Angelica Lucero, Gustavo Perez Ortiz, Annamaria Lilienkampf, Alison N Hulme, Dominic J Campopiano

Journal: Faraday Discuss

PubMed ID: 38856717

Doi: 10.1039/d4fd00016a

Products & Services: Gene Synthesis

Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG antibodies

Authors: Wen-Ting K Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J Carter

Journal: MAbs

PubMed ID: 38845069

Doi: 10.1080/19420862.2024.2362789

Products & Services: Gene Synthesis

Aerobic exercise-induced HIF-1α upregulation in heart failure: exploring potential impacts on MCT1 and MPC1 regulation

Authors: Longfei Xu, Miaomiao Yang, Aili Wei, Zilin Wei, Yingkai Qin, Kun Wang, Bin Li, Kang Chen, Chen Liu, Chao Li, Tianhui Wang

Journal: Mol Med

PubMed ID: 38867145

Doi: 10.1186/s10020-024-00854-3

Products & Services: Protein and Antibody Isolation

MCTP1 increases the malignancy of androgen-deprived prostate cancer cells by inducing neuroendocrine differentiation and EMT

Authors: Yen-Nien Liu, Wei-Yu Chen, Hsiu-Lien Yeh, Wei-Hao Chen, Kuo-Ching Jiang, Han-Ru Li, Phan Vu Thuy Dung, Zi-Qing Chen, Wei-Jiunn Lee, Michael Hsiao, Jiaoti Huang, Yu-Ching Wen

Journal: Sci Signal

PubMed ID: 38861615

Doi: 10.1126/scisignal.adc9142

Products & Services: Protein and Antibody Isolation

Down-regulation of SLC14A1 in prostate cancer activates CDK1/CCNB1 and mTOR pathways and promotes tumor progression

Authors: Jianbin Ma, Kaihua Xue, Yifan Jiang, Xinyang Wang, Dalin He, Peng Guo

Journal: Sci Rep

PubMed ID: 38942821

Doi: 10.1038/s41598-024-66020-1

Products & Services: Molecular Biology Reagents

Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein

Authors: Wenjuan Du, Oliver Debski-Antoniak, Dubravka Drabek, Rien van Haperen, Melissa van Dortmondt, Joline van der Lee, Ieva Drulyte, Frank J M van Kuppeveld, Frank Grosveld, Daniel L Hurdiss, Berend-Jan Bosch

Journal: Nat Commun

PubMed ID: 38909062

Doi: 10.1038/s41467-024-49693-0

Products & Services: DNA Sequencing

Anaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell growth

Authors: Wei-Yun Lai, Tzu-Po Chuang, Marcus Borenäs, Dan E Lind, Bengt Hallberg, Ruth H Palmer

Journal: Cell Death Differ

PubMed ID: 38858548

Doi: 10.1038/s41418-024-01319-0

Products & Services: Molecular Biology Reagents

Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in presence of CD4-mimetics

Authors: Alexandra Tauzin, Lorie Marchitto, Étienne Bélanger, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Jérémie Prévost, Derek Yang, Ta-Jung Chiu, Hung-Ching Chen, Catherine Bourassa, Halima Medjahed, Marek K Korzeniowski, Suneetha Gottumukkala, William D Tolbert, Jonathan Richard, Amos B Smith, Marzena Pazgier, Andrés Finzi

Journal: medrxiv

PubMed ID: 38883797

Doi: 10.1101/2024.06.02.24308281

Products & Services: Catalog Peptides

Oriented immobilization of nanobodies using SpyCatcher/SpyTag significantly enhances the capacity of affinity chromatography

Authors: Yuxiang Zhang, Yao Zhang, Luyao Zhang, Yongdong Liu

Journal: J Chromatogr A

PubMed ID: 38905946

Doi: 10.1016/j.chroma.2024.465107

Products & Services: Molecular Biology Reagents

Enhanced Recombinant Protein Expression in Insect Cells by Natural and Recombinant Components of Lepidoptera Hemolymph

Authors: Javier López-Vidal, Susana Martínez-Pulgarín, Diego Martínez-Alonso, Miguel Cid, José M Escribano

Journal: Viruses

PubMed ID: 38932236

Doi: 10.3390/v16060944

Products & Services: Protein and Antibody Isolation