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Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2
Authors: Qian Wang, Yicheng Guo, Ryan G Casner, Jian Yu, Manoj S Nair, Jerren Ho, Eswar R Reddem, Ian A Mellis, Madeline Wu, Chih-Chen Tzang, Hsiang Hong, Yaoxing Huang, Lawrence Shapiro, Lihong Liu, David D Ho
Journal: Nature Communications
PubMed ID: 40615407
Doi: 10.1038/s41467-025-61472-z
Products & Services: Gene Synthesis   
Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in bacteria
Authors: Belen Sotomayor, Thomas C Donahue, Sai Pooja Mahajan, May N Taw, Sophia W Hulbert, Erik J Bidstrup, D Natasha Owitipana, Alexandra Pang, Xu Yang, Souvik Ghosal, Christopher A Alabi, Parastoo Azadi, Jeffrey J Gray, Michael C Jewett, Lai-Xi Wang, Matthew P DeLisa
Journal: Nature Communications
PubMed ID: 40610439
Doi: 10.1038/s41467-025-61440-7
Products & Services: Peptide Synthesis   
Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
Authors: Tobias Plowman, Tom Hofland, Callum Hall, Rachael Thompson, Judith Pape, Kevin W Ng, Laura Doglio, George Kassiotis
Journal: SCIENCE ADVANCES
PubMed ID: 40614216
Doi: 10.1126/sciimmunol.adr1105
Products & Services: Gene Synthesis   
The mitotic chromosome periphery modulates chromosome mechanics
Authors: Tania Mendonca, Roman Urban, Kellie Lucken, George Coney, Neil M Kad, Manlio Tassieri, Amanda J Wright, Daniel G Booth
Journal: Nature Communications
PubMed ID: 40640170
Doi: 10.1038/s41467-025-61755-5
Products & Services: Gene Synthesis   
Structure-guided engineering of snake toxins for selective modulation of adrenergic and muscarinic receptors
Authors: Yixuan Zhong, Huihui Tao, Yu Zhang, Binbin He, Haizhan Jiao, Dandan Wang, Maikun Teng, Hongli Hu, Qiong Guo, Yuyong Tao
Journal: Nature Communications
PubMed ID: 40659608
Doi: 10.1038/s41467-025-61695-0
Rice E3 ubiquitin ligase BLAST AND BTH-INDUCED 1 targets jasmonic acid signaling co-repressors to release Myelocytomatosis protein 2 for modulating immune responses against blast fungus
Authors: Yan Bi , Yuqing Yan , Hui Wang , Leeza Tariq , Dayong Li , Fengming Song
Journal: International Journal of Biological Macromolecules
PubMed ID: 40543771
Doi: doi.org/10.1016/j.ijbiomac.2025.145363
Products & Services: Catalog Peptides   
LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma
Authors: Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng
Journal: Advanced Science
Doi: doi.org/10.1002/advs.202416809
Products & Services: Peptide Synthesis   
Activation of mechanosensitive ion channel Piezo1 linking metabolic reprogramming and pro-inflammatory responses in hepatocellular carcinoma
Authors: Juanfen Mo, YuXuan Zhang, Chenxi Cao, WeiLi Zheng, Li Zheng, Xiaoguang Wang, Shiyue Wang, Jiayuan Wu, Yi Bao
Journal: Cell Communication and Signaling
PubMed ID: 40514668
Doi: 10.1186/s12964-025-02289-7
Products & Services: Protein and Antibody Isolation   
Topical delivery of a human single-domain antibody targeting IL-33 to inhibit mucosal inflammation
Authors: Keke Huang, Yuqing Wu, Yu Kong, Qingyuan Xu, Mingwei Lv, Yirou Zhang, Yiteng Lu, Quanxiao Li, Cheng Li, Wenping Song, Xiaoyi Zhu, Zhenlin Yang, Changchang Xin, Xujiao Zhou, Tianlei Ying, Yanling Wu, Jiaxu Hong
Journal: Cellular & molecular immunology
PubMed ID: 40500403
Doi: 10.1038/s41423-025-01305-7
Products & Services: Protein and Antibody Isolation   
An all-silk-based functional system promotes tendon regeneration by regulating the cell fate of TSPCs in an inflammatory microenvironment
Authors: Qingyun Mo, Haotian Zheng, Chuanquan Liu, Yuzhi Sun, Zhicheng Cao, Renwang Sheng, Yanan Zhang, Mingyue Wang, Baian Kuang, Ludvig J Backman, Jiaxiang Li, Wei Zhang, Jialin Chen
Journal: Acta Biomaterialia
PubMed ID: 40409996
Doi: 10.1016/j.actbio.2025.05.040
Products & Services: Recombinant Proteins   
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