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Mechanism-based peroxiredoxin 3 inhibitors exploit a covalent warhead for cancer therapy

Authors: Kimberly J Nelson, Terrence L Smalley Jr, Terri Messier, Rajesh Gumpena, Uma Gandhi, Stephanie Milczarek, Aida Habibovic, Hattie Hoffman, Victoria Gibson, Robert J Hondal, W Todd Lowther, Brian Cunniff

Journal: SCIENCE ADVANCES

PubMed ID: 41171914

Doi: 41171914

Baculovirus-Mediated Gene Therapy: Targeting BIRC6 for Lung and Breast Cancer

Authors: Abril Marchesini, Santiago M Gómez Bergna, Leslie C Amorós Morales, María Florencia López, Larisa Vásquez, Silvana E Tongiani, Florencia González Morán, Víctor Romanowski, María Florencia Gottardo, Matias L Pidre

Journal: Viruses

PubMed ID: 41305480

Doi: 10.3390/v17111458

Products & Services: PCR Cloning and Subcloning Plasmid DNA Preparation

Rabies virus-vectored Lyme disease vaccine provides long-term protection against tick-transmitted Borrelia burgdorferi

Authors: Shantel Rios; Bibek Bhattachan; Christoph Wirblich; Anisha Chandwani; Kruthi Vavilikolanu; Jacob F. Myers; Chrysoula Kitsou; Utpal Pal; Matthias J. Schnell

Journal: npj Vaccines

PubMed ID: 41233361

Doi: 10.1038/s41541-025-01294-8

Rabies virus-vectored Lyme disease vaccine provides long-term protection against tick-transmitted Borrelia burgdorferi

Authors: Shantel Rios; Bibek Bhattachan; Christoph Wirblich; Anisha Chandwani; Kruthi Vavilikolanu; Jacob F. Myers; Chrysoula Kitsou; Utpal Pal; Matthias J. Schnell

Journal: npj Vaccines

PubMed ID: 41233361

Doi: 10.1038/s41541-025-01294-8

Protocol for production and characterization of SARS-CoV-2 PL pro in Escherichia coli

Authors: Anna De Falco; Rebecca Greene-Cramer; Ben A. Shurina; Suren Zakian; Thomas B. Acton; Theresa A. Ramelot; Gaetano T. Montelione

Journal: STAR Protocols

PubMed ID: 40682779

Doi: 10.1016/j.xpro.2025.103952

Pocket Crafter: a 3D generative modeling based workflow for the rapid generation of hit molecules in drug discovery

Authors: Lingling Shen; Jian Fang; Lulu Liu; Fei Yang; Jeremy L. Jenkins; Peter S. Kutchukian; He Wang

Journal: Journal of Cheminformatics

PubMed ID: 38515171

Doi: 10.1186/s13321-024-00829-w

Products & Services: Peptide Synthesis

Elucidating the Substrate Envelope of Enterovirus 68-3C Protease: Structural Basis of Specificity and Potential Resistance

Authors: Vincent N. Azzolino; Ala M. Shaqra; Akbar Ali; Nese Kurt Yilmaz; Celia A. Schiffer

Journal: Viruses

PubMed ID: 39339895

Doi: 10.3390/v16091419

Products & Services: Peptide Synthesis

Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3

Authors: Adina-Gabriela Vasilescu; Andrei-Mihai Vasilescu; Livia Elena Sima; Natalia Baran; tefan-Eugen Szedlacsek

Journal: Frontiers in pharmacology

PubMed ID: 41031165

Doi: 10.3389/fphar.2025.1673427

Pocket Crafter: a 3D generative modeling based workflow for the rapid generation of hit molecules in drug discovery

Authors: Lingling Shen; Jian Fang; Lulu Liu; Fei Yang; Jeremy L. Jenkins; Peter S. Kutchukian; He Wang

Journal: Journal of Cheminformatics

PubMed ID: 38515171

Doi: 10.1186/s13321-024-00829-w

Products & Services: Peptide Synthesis

Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3

Authors: Adina-Gabriela Vasilescu; Andrei-Mihai Vasilescu; Livia Elena Sima; Natalia Baran; tefan-Eugen Szedlacsek

Journal: Frontiers in pharmacology

PubMed ID: 41031165

Doi: 10.3389/fphar.2025.1673427