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Protocol for production and characterization of SARS-CoV-2 PL pro in Escherichia coli
Authors: Anna De Falco; Rebecca Greene-Cramer; Ben A. Shurina; Suren Zakian; Thomas B. Acton; Theresa A. Ramelot; Gaetano T. Montelione
Journal: STAR Protocols
PubMed ID: 40682779
Doi: 10.1016/j.xpro.2025.103952
An AI-derived peptide PCa2 suppresses pancreatic cancer growth via modulation of the ErbB/PI3K/AKT/mTOR/MYC signaling axis
Authors: Weimin Zuo; Siyuan Luo; Haixin Qin; Koon Ho Wong; Shirley W. I. Siu; Alexandre K. Tashima; Yehuda G. Assaraf; Hang Fai Kwok
Journal: Cell Communication and Signaling : CCS
PubMed ID: 41957678
Doi: 10.1186/s12964-026-02856-6
Products & Services: Peptide Synthesis   
A D-Phenylalanine-Benzoxazole Derivative Reveals the Role of the Essential Enzyme Rv3603c in the Pantothenate Biosynthetic Pathway of Mycobacterium tuberculosis
Authors: Michael J. Pepi; Shibin Chacko; Gary M. Marqus; Vinayak Singh; Zhe Wang; Kyle Planck; Ryan T. Cullinane; Penchala N. Meka; Deviprasad R. Gollapalli; Thomas R. Ioerger; Kyu Y. Rhee; Gregory D. Cuny; Helena I.M. Boshoff; Lizbeth Hedstrom
Journal: ACS Infectious Diseases
PubMed ID: 35015509
Doi: 10.1021/acsinfecdis.1c00461
Guidelines in the Preparation of Fully Synthetic, Human Single-Domain Antibody Phage Display Libraries
Authors: Mark A. Tornetta; Brian P. Whitaker; Olivia M. Cantwell; Peter N. Haytko; Eileen D. Pisors; Fulai Zhou; Mark L. Chiu
Journal: Antibodies
PubMed ID: 40843683
Doi: 10.3390/antib14030071
Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria
Authors: Hannah E. Snoke; Stephanie M. Reeve; Suresh Dharuman; Miranda J. Wallace; Victoria C. Loudon; Ying Zhao; John J. Bowling; Patricia A. Murphy; Brett Waddell; Robin B. Lee; J rgen B. Bulitta; Richard E. Lee
Journal: ACS Infectious Diseases
PubMed ID: 41116192
Doi: 10.1021/acsinfecdis.5c00635
A human-specific regulatory mechanism revealed in a pre-implantation model
Authors: Raquel Fueyo, Sicong Wang, Olivia J. Crocker, Tomek Swigut, Hiromitsu Nakauchi & Joanna Wysocka
Journal: Nature
PubMed ID: 41034587
Doi: 10.1038/s41586-025-09571-1
DLFea4AMPGen de novo design of antimicrobial peptides by integrating features learned from deep learning models
Authors: Han Gao, Feifei Guan, Boyu Luo, Dongdong Zhang, Wei Liu, Yuying Shen, Lingxi Fan, Guoshun Xu, Yuan Wang, Tao Tu, Ningfeng Wu, Bin Yao, Huiying Luo, Yue Teng, Jian Tian, Huoqing Huang
Journal: Nature Communications
PubMed ID: 41093853
Doi: 10.1038/s41467-025-64378-y
Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy
Authors: Yu Fu, Yulan Huang, Yunjiao Wang, Zhenlan Fu, Wenyun Cai, Lu Wang, Yuchun Wu, Xing Zhou, Zhongyi Ma, Zhigang Xu, Yaqin Tang, Jing Xie, Jiayun Jiang, Robert J. Lee & Chong Li
Journal: Nature Communications
PubMed ID: 41102140
Doi: 10.1038/s41467-025-64212-5
DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage
Authors: Zihui Yan, Guanjin Qu, Xin Chen, Gang Zheng & Huaming Wu
Journal: Nature Communications
PubMed ID: 41102205
Doi: 10.1038/s41467-025-64230-3
The nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection
Authors: Tai-Ting Woo, Yuka Takeo, Mara C Harwood, Ethan T Houck, Daniel DiMaio, Billy Tsai
Journal: SCIENCE ADVANCES
PubMed ID: 41124246
Doi: 10.1126/sciadv.adz6792
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