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Chemically Synthesized H3K14Ub Unveils Clr4's IDR-Mediated Multivalent Nucleosome Recognition in H3K9 Methylation

Authors: Maoshen Sun, Yunxiang Du, Zhengqing Li, Akejiang Aderjiang, Meixuan Xin, Huasong Ai

Journal: ANGEWANDTE CHEMIE International Edition

PubMed ID: 41873495

Doi: 10.1002/anie.202520817

Products & Services: Gene Synthesis

TMEM187 is a novel modulator in the regulation of erythropoiesis

Authors: Yutong Liu, Wenxin Zhang, Jing Cai, Di Zhou, Hongting Zhao, Weichen Dong, Biao Zhao, Yao Lu, Shuangying Hao, Yibing Ding, Nizhen Jiang, Tong Qiao, Kuanyu Li

Journal: Blood

PubMed ID: 41824385

Doi: 10.1182/blood.2025031135

Products & Services: Cell Isolation

N-Acetylcysteine–Mediated Surface Remodeling of Inhaled mRNA Lipid Nanoparticles Enables Coordinated Mucosal and Systemic Antitumor Immunity

Authors: Xingdi Cheng, Qing Li, Haowei Zu, Shuai Liu, Jingjiao Li, Yixing Wen, Chen Yang, Simin Sun, Haoyu Lu, Yuzhou Zhang, Yumeng Zhao, Guizhi Shi, Meng Qin, Xueguang Lu

Journal: ADVANCED MATERIALS

PubMed ID: 42124519

Doi: doi.org/10.1002/adma.73362

Products & Services: Gene Synthesis

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Authors: Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu

Journal: Advanced Science

PubMed ID: 41787915

Doi: 10.1002/advs.202520157

Products & Services: Protein Electrophoresis and Western

Y-shaped nanoprobe-based DNA microarray for rapid detection of multiplex miRNAs with single-nucleotide specificity

Authors: Yichen Du, Rui Sun, Shuang Hao, Fuwan Yang, Qifei Hu, Ruyan Xue

Journal: Microchemical Journal

Doi: 10.1016/j.microc.2026.117169

Products & Services: Custom DNA/RNA Oligos

A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

Authors: Qianwen Mu, Haolan Deng, Shuo Li, Xiaoyu An, Xuan Liu, Yue Xi, Hao Liang, Di Sun, Xiaojun Wang, Xue Liu, Gang Liu, Chao Liu

Journal: Nature Communications

PubMed ID: 41917023

Doi: 10.1038/s41467-026-71363-6

Products & Services: Peptide Synthesis Protein Electrophoresis and Western

High-Entropy Alloy Synergized with Gene Editing for Cocktail-Sensitized Radioimmunotherapy of Lung Metastases

Authors: Qianglan Lu, Chengwei Ye, Ruiyue Chen, Zhanqi Xing, Zhiyong Liu, Fei Zeng, Jinglang Gong, Yanfeng Gao, Xiaolian Sun, Shaochun Tang, Yujun Song

Journal: ADVANCED MATERIALS

PubMed ID: 41914367

Doi: 10.1002/adma.202522618

Products & Services: Synthetic Guide RNA

89Zr/177Lu-Labeled Radioimmunoconjugates Targeting SORT1 for Cancer Theranostics

Authors: Jingyue Gao, Tianyi Cen, Junyi Chen, Xinwei Li, Xiaowei Fan, Mengxin Xu, Feng Gao, Zhibo Liu

Journal: Journal of Medicinal Chemistry

PubMed ID: 41773941

Doi: 10.1021/acs.jmedchem.6c00007

Products & Services: Custom Vector Construction

CRISPR/Cas9-Based Vanadium MXene-Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal-Induced Multi-Effect Synergistic Antitumor Therapy

Authors: Zi-Jian Huang, Feng-Ming Li, Yi-Fan Tu, Ke-Ke Feng, Cheng-Lei Li, Shi-Cheng Tian, Yong-Shan Hu, Jing-Wei Shao, Zhen-Hua Liu

Journal: Advanced Science

PubMed ID: 41818620

Doi: 10.1002/advs.202522535

Products & Services: Peptide Synthesis

Cyclic guanosine monophosphate-protein kinase G signaling attenuates aortic valve calcification through ULK1-mediated autophagy

Authors: Yan Wang, Fei Xu, Chengxiang Song, Xi Wang, Hao Zhou, Tianyi Qu, Hongde Li, Qiang Luo, Wenhua Lei, Yue Yin, Fangyang Huang, Mao Chen

Journal: Signal transduction and targeted therapy

PubMed ID: 41820291

Doi: 10.1038/s41392-026-02624-5

Products & Services: Custom mRNA synthesis