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ZBTB16 controls the onset of Clostridium difficile colitis through the Pyrin inflammasome

Authors: Shuhui Li, Jingjing He, Huxidanmu Tuoheniyazi, Junrui Ma, Zhenyu Li, Juanjuan Zheng, Yuxin Wang, Xiupan Gao, Xiaobao Yang, Danping Liu, Yanan Zhao, Tongxuan Su, Yibing Peng, Dakang Xu, Xuefeng Fei

Journal: Pharmacological research

PubMed ID: 41666999

Doi: 10.1016/j.phrs.2026.108133

Products & Services: Protein Electrophoresis and Western

Regulated transformation system (RTS): sddi-mediated programmable shut-off and mode switching of base editors

Authors: Jiacheng Deng, Jian Zhou, Hongyong Xiang, Xueyuan Li, Xiang Han, Zhen Weng, Junbo Jia, Yingshuo Shao, Yang Sima, Ming Niu, Dongmeng Li, Hongsheng Ouyang, Bin Xu, Daxin Pang, Lin Yang, Hongming Yuan

Journal: Nucleic Acids Research

PubMed ID: 41909950

Doi: doi.org/10.1093/nar/gkag162

Products & Services: Gene Synthesis Codon Optimization

Ferrous fluoride nanoinitiators reprogram tumor stemness to empower ultrasound-augmented pyroptosis for potent catalytic immunotherapy

Authors: Shumin Sun, Nailin Yang, Jihu Nie, Zifan Pei, Chunjie Wang, Zixian Yang, Zhihui Han, Yichi Cai, Liang Cheng

Journal: Biomaterials

PubMed ID: 40885147

Doi: 10.1016/j.biomaterials.2025.123652

Products & Services: Protein Electrophoresis and Western

Sertoli Cell-Derived Extracellular Vesicles Orchestrate Cadmium-Induced Testicular Inflammation and Fibrosis

Authors: Jianfeng Ma, Mailin Gan, Shuang Liang, Siyu Chen, Ziling Hao, Yiting Yang, Jiawei Lu, Qihang Wu, Yuqian Shi, Lijun Sun, Jiaxin Li, Saihao Wang, Yan Wang, Xiaofeng Zhou, Lei Chen, Ye Zhao, Li Zhu, Linyuan Shen

Journal: Advanced Science

PubMed ID: 41881035

Doi: 10.1002/advs.202522278

Products & Services: Protein Electrophoresis and Western

Chemoenzymatic synthesis of K29/K48-branched ubiquitin chains using LbPro* andOaAEP1 enzymes

Authors: Hongyi Cai, Xiangwei Wu, Shidian Wu, Lei Liu, Man Pan

Journal: CCS Chemistry

Doi: 10.31635/ccschem.026.202506451

Products & Services: Protein Electrophoresis and Western

Elucidating the Molecular Mechanism of 3D1 Antibody Binding to a Swine Enteric Coronavirus Antigen

Authors: Liangminghui Zhang, Ze Liang, Guang Yang, Lei Yan

Journal: Viruses

PubMed ID: 41754551

Doi: 10.3390/v18020208

Products & Services: Peptide Synthesis

ITGB1 Regulates Triple-Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Authors: Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T Rosen, Yingyu Wang, Chun-Wei D Chen, Cheng Zhang, Mingye Feng

Journal: Advanced Science

PubMed ID: 41632816

Doi: 10.1002/advs.202513672

Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity

Authors: Han Wu, Qing Shui, Xiaoxi Luan, Kexin Wang, Wei Zhao, Xiaopeng Qi, Bingyu Liu, Wanwei Sun, Chengjiang Gao

Journal: Molecular Therapy

PubMed ID: 41678331

Doi: 10.1016/j.celrep.2026.116976

Products & Services: Recombinant Proteins

An orthogonal CRISPR/Cpf1 platform for precise spatiotemporal gene regulation and osteoporotic fracture repair

Authors: Jie Zhao, Zengliang Wang, Lina Lu, Guoyun Bu, Zukang Miao, Yang Zhang, Yue Guo, Zhao Yang, Jianxiong Ma, Jun Jiao, Xinlong Ma

Journal: Molecular Therapy

PubMed ID: 41679307

Doi: 10.1016/j.crmeth.2025.101299

Phloretin targeting the 3CLpro Cys144 exhibits broad-spectrum antiviral activity against swine enteric coronavirus

Authors: Jiawei Xiao, Donghua Guo, Xiaoxu Xing, Limin Jiang, Shanshan Qi, Jun Wang, Wenfei Bai, Shiping Yu, Fanbo Shen, Xingyang Guo, Xinglin Wang, Wei Zhou, Hansong Li, Feiyu Zhao, Li Feng, Jialin Zhang, Yaru Xu, Dan Yang, Haixin Liu, Dongbo Sun

Journal: Molecular Therapy

PubMed ID: 41720346

Doi: 10.1016/j.virs.2026.02.011

Products & Services: Peptide Synthesis