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Developmentally endothelial locus-1 facilitates intestinal inflammation resolution by suppressing the Cmpk2-cGAS-STING pathway and promoting reparatory macrophage transition
Authors: Meihui Tao, Li Wang, Chaoyue Chen, Mengfan Tang, Yanping Wang, Jingyue Zhang, Xi Zhao, Qinyu Feng, Junfa Chen, Wei Yan, Rong Lin, Yu Fu
Journal: Journal of Advanced Research
PubMed ID: 40288675
Doi: 10.1016/j.jare.2025.04.030
Products & Services: Mammalian Expression   Recombinant Proteins   
An evolutionarily unique viral RdRP suggests a common dual-function feature of the priming element
Authors: Hengxia Jia, Shunli Liu, Guibo Rao, Qiaojie Liu, Jiqin Wu, Sheng Cao, Peng Gong
Journal: Sci Adv
PubMed ID: 40249801
Doi: 10.1126/sciadv.adv9640
Products & Services: Gene Synthesis   Custom Vector Construction   
Identification of RC3H1 as antiviral host factor binding to the non-structural protein 1 of Influenza A virus via a 3-stage computational pipeline and cell-based analysis
Authors: Swee Teng Teo , Shamima Rashid , Kong Yen Liew , Kah Man Lai , Teng Ann Ng , Jifeng Jiao , Chee Keong Kwoh , Yee-Joo Tan
Journal: Virology Journal
PubMed ID: 40287742
Doi: 10.1186/s12985-025-02746-2
Products & Services: ORF cDNA Clones/MolecularCloud   
Fused exosomal targeted therapy in periprosthetic osteolysis through regulation of bone metabolic homeostasis
Authors: Tianliang Ma, Qimeng Liu, Zheyu Zhang, Jiangyu Nan, Guanzhi Liu, Yute Yang, Yihe Hu, Jie Xie
Journal: Bioactive Materials
PubMed ID: 40248188
Doi: doi.org/10.1016/j.bioactmat.2025.04.006
Phosphorylation dependent charge block regulate the relaxation of nuclear speckle networks
Authors: Mengjun Zhang, Zhuang Gu, Yingtian Sun, Yichen Dong, Junlin Chen, Li Shu, Suibin Ma, Jierui Guo, Yuhang Liang, Qingming Qu, Ning Fang, Chuan-Qi Zhong, Yifan Ge, Zhongwen Chen, Shaohui Huang, Xin Zhang, Bo Wang
Journal: Mol Cell
PubMed ID: 40233760
Doi: 10.1016/j.molcel.2025.03.016
N-Terminal random curl-tandam α-helical peptide 7W: A potent antibacterial and anti-inflammatory dual-effect agent through tryptophan substitution
Authors: Jietao Lou, Xinyi Wu, Wenwen Ji, Jiaye Yu, Yanyan Xu, Wanyang Xiao, Weijie Lu, Kaiyun Xin, Tianbao Chen, Qidong Tang, Guang Liang, Yitian Gao, Di Wu
Journal: Eur J Med Chem
PubMed ID: 40319576
Doi: 10.1016/j.ejmech.2025.117686
Products & Services: Peptide Synthesis   
Targeted Delivery of mRNA with Polymer−Lipid Nanoparticles for In Vivo Base Editing
Authors: Qimingxing Chen, Yan Chang, Xiaoyan He, Yan Ding, Runyuan Wang, Ran Luo, Jialu Yuan, Jiabei Chen, Guisheng Zhong, Huiying Yang, Jia Chen, Jianfeng Li
Journal: ACS Nano
PubMed ID: 39962883
Doi: 10.1021/acsnano.4c14041
Fullerol Initiates Stem Cell–Nanomaterials Interactions for Enhanced Tissue Regeneration via Clathrin-Mediated Endocytosis and Nuclear Factor Erythroid 2-Related Factor 2 Signaling
Authors: Haoyang Liu, Yue Zhu, Weixu Chen, Renwang Sheng, Chuanquan Liu, Yuzhi Sun, Jia Liu, Mingyue Wang, Jun Lu, Jialin Chen, Wei Zhang
Journal: ACS Applied Materials & Interfaces
Doi: 10.1021/acsami.5c01731
Products & Services: Recombinant Proteins   
PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance
Authors: Anoop S Chauhan, Matthew J W Mackintosh, Joseph Cassar, Alexander J Lanz, Mohammed Jamshad, Hannah L Mackay, Alexander J Garvin, Alexandra K Walker, Satpal S Jhujh, Teresa Carlomagno, Aneika C Leney, Grant S Stewart, Joanna R Morris
Journal: Nature Communication
PubMed ID: 40229270
Doi: 10.1038/s41467-025-56974-9
Products & Services: Peptide Synthesis   Monoclonal Antibody Services   
Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration
Authors: Zhuo Li, Zhengnan Guo, Zhengmeng Yang, Boguang Yang, Yuan Hu, Xian Xie, Zhixian Zong, Zekun Chen, Kunyu Zhang, Pengchao Zhao, Gang Li, Xuefeng Yang, Liming Bian
Journal: Cell Rep
PubMed ID: 40272981
Doi: 10.1016/j.celrep.2025.115611
Products & Services: Peptide Synthesis   

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