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Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Authors: Yuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu, Kexin Chen, Muna Alariqi, Junping Gao, Zhanjun Li, Shuangxia Jin

Journal: Genome Biology

PubMed ID: 41250247

Doi: doi.org/10.1186/s13059-025-03849-3

Products & Services: Gene Fragments

RBM39 Contributes to MGMT Maintenance in Response to Temozolomide-Induced DNA Damage

Authors: Vahid Khalaj, Jack T Adams, Solmaz AghaAmiri, Servando Hernandez Vargas, Tyler M Bateman, Sukhen C Ghosh, Majid Momeny, Ali Azhdarinia

Journal: Cancers

PubMed ID: 41300971

Doi: 10.3390/cancers17223604

Products & Services: Protein Electrophoresis and Western

Amplification-free cancer diagnosis based on inhibition of Cas12a activity by site-specific 5mC-modified cfDNA

Authors: Feng Yang, Can Xu, Chunhong Li, Xinni Xiang, Yi Zhao, Cong Hu, Huan Rong, Yu He, Jingyu Li, Yu Wang, Chao Tang, Xiaoyu Liu, Renyan Li, Fei Deng, Tingxiu Xiang

Journal: Nucleic Acids Research

PubMed ID: 41404798

Doi: doi.org/10.1093/nar/gkaf1383

Products & Services: Catalog Gene Editing

Intravaginal delivery of mRNA-encoded antibodies with enhanced breadth and potency for SHIV/HIV protection

Authors: Jae Yeon Joo, Peng Xiao, Susan P John, Daryll Vanover, Hannah E Peck, Loren E Sasser, Deepanwita Bose, Younghun Jung, Jaehyeon Hwang, Chiara Zurla, Francois Villinger, Philip J Santangelo

Journal: Nature Communications

PubMed ID: 41290645

Doi: doi.org/10.1038/s41467-025-65456-x

Products & Services: Gene Synthesis Catalog Antibodies

Potential of ferulic acid as a food-derived cardioprotective agent targeting mitochondrial dysfunction

Authors: Duanrui Cao, Lina Huang, Xiaowei Lu, Junhua Meng, Wenhong Li, Delin Duan, Qianqian Wang, Cuiping Liu, Zidong Qiu, Ni Zhang

Journal: Food Bioscience

Doi: //doi.org/10.1016/j.fbio.2025.107704

Products & Services: Custom DNA/RNA Oligos

Enhanced antigen presentation by macrophages promotes human atherosclerosis progression: therapeutic implications

Authors: Yuhuai Xie, Que Wu, Yunhui Jia, Lianping Cheng, Yaru Tian, Xian Yang, Wei Wang, Wei Xu, Zhen Zhao, Yuanyuan Wei

Journal: European heart journal

PubMed ID: 41217874

Doi: 10.1093/eurheartj/ehaf878

Products & Services: Synthetic Guide RNA

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

Authors: Grzegorz P. Bereta， Ewa Bielecka， Karolina Marzec， Łukasz Pijanowski， Artur P. Biela， Piotr Wilk， Marta Kamińska， Jakub Nowak， Elżbieta Wątor-Wilk， Przemysław Grudnik， Dominik Kowalczyk， Joanna Kozieł， Piotr Mydel， Marcin Poręba， Tomasz Kantyka

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41166417

Doi: doi.org/10.1073/pnas.2508369122

Products & Services: Gene Synthesis

SmallTalk: a novel small-sized fusion tag for peptide expression and purification

Authors: Atika Tariq, Nestor G Casillas-Vega, Alma Gomez-Loredo, Xristo Zarate

Journal: FEBS Open Bio

PubMed ID: 41220226

Doi: 10.1002/2211-5463.70147

Products & Services: Gene Synthesis

Structural insights into antagonist recognition by the vasopressin V2 receptor

Authors: Tianwei Zhang, Hongli Liu, Chongzhao You, Yixiao Zhang, Youwei Xu, Benxun Pan, Canrong Wu, Sanshan Jin, Yu-Ling Yin, Kai Wu, Yue Chen, Hong Sun, Yuan Si, Yangxia Tan, Wanchao Yin, H Eric Xu, Dong Guo, Yi Jiang

Journal: Nature Communications

PubMed ID: 41188237

Doi: 10.1038/s41467-025-64735-x

Products & Services: Protein and Antibody Isolation

De novo designed voltage-gated anion channels suppress neuron firing

Authors: Chen Zhou, Huican Li, Jiaxing Wang, Cheng Qian, Hui Xiong, Zhilin Chu, Qiming Shao, Xuan Li, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M Gamal El-Din, Bo Li, Jing Huang, Kun Wu, Peilong Lu

Journal: Cell

PubMed ID: 41106381

Doi: 10.1016/j.cell.2025.09.023

Products & Services: Protein and Antibody Isolation