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Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection

Authors: Zhao-Shan Chen, Hsiang-Chi Huang, Xiangkun Wang, Karin Schön, Yane Jia, Michael Lebens, Danica F. Besavilla, Janarthan R. Murti, Yanhong Ji, Aishe A. Sarshad, Guohua Deng, Qiyun Zhu & Davide Angeletti

Journal: Nature Communications

PubMed ID: 39788944

Doi: 10.1038/s41467-024-55193-y

Products & Services: Catalog Antibodies

Identification of a binding site for small molecule inhibitors targeting human TRPM4

Authors: Babatunde Ekundayo, Prakash Arullampalam, Christian E. Gerber, Anne-Flore Hämmerli, Sabrina Guichard, Mey Boukenna, Daniela Ross-Kaschitza, Martin Lochner, Jean-Sebastien Rougier, Henning Stahlberg, Hugues Abriel & Dongchun Ni

Journal: Nature Communications

PubMed ID: 39828793

Doi: 10.1038/s41467-025-56131-2

Products & Services: Mutagenesis Services

Barcoded SARS-CoV-2 viruses define the impact of duration and route of exposure on the transmission bottleneck in a hamster model

Authors: Reed Trende , Tamarand L Darling , Tianyu Gan , David Wang , Adrianus C M Boon

Journal: SCIENCE ADVANCES

PubMed ID: 39813353

Doi: 10.1126/sciadv.ads2927

Products & Services: Gene Synthesis

Microenvironment actuated CAR T cells improve solid tumor efficacy without toxicity

Authors: Kristen C Vogt , Pedro C Silberman , Qianqian Lin , James E Han , Amy Laflin , Hendryck A Gellineau , Daniel A Heller , David A Scheinberg

Journal: SCIENCE ADVANCES

PubMed ID: 39841845

Doi: 10.1126/sciadv.ads3403

Products & Services: Gene Synthesis

Direct repeat region 3’ end modifications regulate Cas12a activity and expand its applications

Authors: Wei Zhang , Yinyin Zhong , Jiaqi Wang , Guangrong Zou , Qiaozhen Chen , Chaoxing Liu

Journal: Nucleic Acids Res

PubMed ID: 39883010

Doi: 10.1093/nar/gkaf040

Products & Services: PCR Cloning and Subcloning

An Insect Eﬀector Mimics Its Host Immune Regulator to Undermine Plant Immunity

Authors: Jianmei Fu , Shuai Li , Jing Li , Zhichang Zhao , Jing Li , Xinyang Tan , Shan Yu , Maofeng Jing , Keyan Zhu-Salzman , Jichao Fang , Rui Ji

Journal: Adv Sci (Weinh)

PubMed ID: 39853648

Doi: doi.org/10.1002/advs.202409186

Products & Services: Peptide Synthesis

Light signal regulates endoreduplication and tomato fruit expansion through the SlPIF1a-SlTLFP8-SlCDKB2 module

Authors: Jiaojiao Zhang, Jiayi Xu, Xinman Wang, Ying Liu, Shuangtao Li, Jialong Zhang, Lingfeng He, Luqin Guo, Chonghua Li, Xin-Xu Li, Yang-Dong Guo, Na Zhang

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 39847324

Doi: 10.1073/pnas.2404445122

Products & Services: Polyclonal Antibody Services

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1

Authors: Fanchong Jian, Jing Wang, Ayijiang Yisimayi, Weiliang Song, Yanli Xu, Xiaosu Chen, Xiao Niu, Sijie Yang, Yuanling Yu, Peng Wang, Haiyan Sun, Lingling Yu, Jing Wang, Yao Wang, Ran An, Wenjing Wang, Miaomiao Ma, Tianhe Xiao, Qingqing Gu, Fei Shao, Youchun Wang, Zhongyang Shen, Ronghua Jin, Yunlong Cao

Journal: Nature

PubMed ID: 39510125

Doi: 10.1038/s41586-024-08315-x

Products & Services: Gene Synthesis Codon Optimization

Divergent evolution of opposite base specificity and single-stranded DNA activity in animal and plant AP endonucleases

Authors: Marina Jordano-Raya, Carol E Schrader, Rafael R Ariza, Teresa Roldán-Arjona, Dolores Córdoba-Cañero

Journal: Nucleic Acids Research

PubMed ID: 39778867

Doi: 10.1093/nar/gkae1297

Products & Services: Codon Optimization

Spontaneous base flipping helps drive Nsp15’s preferences in double stranded RNA substrates

Authors: Zoe M. Wright, Kevin John Butay, Juno M. Krahn, Isha M. Wilson, Scott A. Gabel, Eugene F. DeRose, Israa S. Hissein, Jason G. Williams, Mario J. Borgnia, Meredith N. Frazier, Geoffrey A. Mueller & Robin E. Stanley

Journal: Nature Communications

PubMed ID: 39755678

Doi: 10.1038/s41467-024-55682-0