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Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT

Authors: Xuefang Pan, Mahsa Taherzadeh, Poulomee Bose, Rachel Heon-Roberts, Annie L A Nguyen, TianMeng Xu, Camila Pará, Yojiro Yamanaka, David A Priestman, Frances M Platt, Shaukat Khan, Nidhi Fnu, Shunji Tomatsu, Carlos R Morales, Alexey V Pshezhetsky

Journal: J Exp Med

PubMed ID: 35704026

Doi: 10.1084/jem.20211860

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A paper-based optical sensor for the screening of viruses through the cysteine residues of their surface proteins: A proof of concept on the detection of coronavirus infection

Authors: Mahnaz D Gholami, Kristyan Guppy-Coles, Serena Nihal, Daman Langguth, Prashant Sonar, Godwin A Ayoko, Chamindie Punyadeera, Emad L Izake

Journal: Talanta

PubMed ID: 35660992

Doi: 10.1016/j.talanta.2022.123630

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Zika Virus Envelope Protein Domain III Produced in Has the Potential for Diagnostic Applications

Authors: John Willians Oliveira Prates, Mariana Fonseca Xisto, João Vitor da Silva Rodrigues, João Pedro Cruz Colombari, Júlia Maria Alves Meira, Roberto Sousa Dias, Cynthia Canedo da Silva, E Sérgio Oliveira de Paula

Journal: Diagnostics (Basel)

PubMed ID: 35626353

Doi: 10.3390/diagnostics12051198

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Clade-Specific Alterations within the HIV-1 Capsid Protein with Implications for Nuclear Translocation

Authors: Alexej Dick, Megan E Meuser, Simon Cocklin

Journal: Biomolecules

PubMed ID: 35625621

Doi: 10.3390/biom12050695

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Identifying Small-Molecule Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase by Establishing a Fluorometric Assay

Authors: Xiaoming Bai, Hongmin Sun, Shuo Wu, Yuhuan Li, Lifei Wang, Bin Hong

Journal: Front Immunol

PubMed ID: 35464436

Doi: 10.3389/fimmu.2022.844749

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The recombinant defensin/HSA fusion protein that inhibits NF-κb associated with intensive macropinocytosis shows potent efficacy against pancreatic cancer

Authors: Yi-Bo Du, Xiao-Fei Wang, Xiu-Jun Liu, Yi Li, Qing-Fang Miao, Min Jiang, Wei-Jin Sheng, Yong-Su Zhen

Journal: Biochem Pharmacol

PubMed ID: 35489393

Doi: 10.1016/j.bcp.2022.115057

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Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation

Authors: Koen K A Van Rompay, Katherine J Olstad, Rebecca L Sammak, Joseph Dutra, Jennifer K Watanabe, Jodie L Usachenko, Ramya Immareddy, Jamin W Roh, Anil Verma, Yashavanth Shaan Lakshmanappa, Brian A Schmidt, Clara Di Germanio, Nabeela Rizvi, Hongwei Liu, Zhong-Min Ma, Mars Stone, Graham Simmons, Larry J Dumont, A Mark Allen, Sarah Lockwood, Rachel E Pollard, Rafael Ramiro de Assis, JoAnn L Yee, Peter B Nham, Amir Ardeshir, Jesse D Deere, Aarti Jain, Philip L Felgner, Lark L Coffey, Smita S Iyer, Dennis J Hartigan-O'Connor, Michael P Busch, J Rachel Reader

Journal: PLoS Pathog

PubMed ID: 35443018

Doi: 10.1371/journal.ppat.1009925

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A simple method to determine changes in the affinity between HisF and HisH in the Imidazole Glycerol Phosphate Synthase heterodimer

Authors: Vitor M Almeida, J Patrick Loria, Sandro R Marana

Journal: PLoS ONE

PubMed ID: 35452497

Doi: 10.1371/journal.pone.0267536

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Structure of SNX9 SH3 in complex with a viral ligand reveals the molecular basis of its unique specificity for alanine-containing class I SH3 motifs

Authors: Helena Tossavainen, Hasan Uğurlu, Mikael Karjalainen, Maarit Hellman, Lina Antenucci, Riku Fagerlund, Kalle Saksela, Perttu Permi

Journal: Structure

PubMed ID: 35390274

Doi: 10.1016/j.str.2022.03.006

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Theileria equi RAP-1a and RAP-1b proteins contain immunoreactive epitopes and are suitable candidates for vaccine and diagnostics development

Authors: Cynthia K Onzere, Lindsay M Fry, Richard P Bishop, Marta Da Silva, Sally A Madsen-Bouterse, Reginaldo G Bastos, Donald P Knowles, Carlos E Suarez

Journal: Int J Parasitol

PubMed ID: 35318949

Doi: 10.1016/j.ijpara.2022.01.004

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