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Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT

Authors: Xuefang Pan, Mahsa Taherzadeh, Poulomee Bose, Rachel Heon-Roberts, Annie L A Nguyen, TianMeng Xu, Camila Pará, Yojiro Yamanaka, David A Priestman, Frances M Platt, Shaukat Khan, Nidhi Fnu, Shunji Tomatsu, Carlos R Morales, Alexey V Pshezhetsky

Journal: J Exp Med

PubMed ID: 35704026

Doi: 10.1084/jem.20211860

Products & Services: Recombinant Antibody Expression

Kinetics of immune responses to SARS-CoV-2 proteins in individuals with varying severity of infection and following a single dose of the AZD1222

Authors: Deshni Jayathilaka, Chandima Jeewandara, Laksiri Gomes, Tibutius Thanesh Pramanayagam Jayadas, Achala Kamaladasa, Gayasha Somathilake, Dinuka Guruge, Pradeep Darshana Pushpakumara, Thushali Ranasinghe, Inoka Sepali Aberathna, Saubhagya Danasekara, Buddini Gunathilaka, Heshan Kuruppu, Ananda Wijewickrama, Ruwan Wijayamuni, Lisa Schimanski, T K Tan, Graham S Ogg, Alain Townsend, Gathsaurie Neelika Malavige

Journal: Clin Exp Immunol

PubMed ID: 35641142

Doi: 10.1093/cei/uxac009

Products & Services: Recombinant Antibody Expression

Zika Virus Envelope Protein Domain III Produced in Has the Potential for Diagnostic Applications

Authors: John Willians Oliveira Prates, Mariana Fonseca Xisto, João Vitor da Silva Rodrigues, João Pedro Cruz Colombari, Júlia Maria Alves Meira, Roberto Sousa Dias, Cynthia Canedo da Silva, E Sérgio Oliveira de Paula

Journal: Diagnostics (Basel)

PubMed ID: 35626353

Doi: 10.3390/diagnostics12051198

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A paper-based optical sensor for the screening of viruses through the cysteine residues of their surface proteins: A proof of concept on the detection of coronavirus infection

Authors: Mahnaz D Gholami, Kristyan Guppy-Coles, Serena Nihal, Daman Langguth, Prashant Sonar, Godwin A Ayoko, Chamindie Punyadeera, Emad L Izake

Journal: Talanta

PubMed ID: 35660992

Doi: 10.1016/j.talanta.2022.123630

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Clade-Specific Alterations within the HIV-1 Capsid Protein with Implications for Nuclear Translocation

Authors: Alexej Dick, Megan E Meuser, Simon Cocklin

Journal: Biomolecules

PubMed ID: 35625621

Doi: 10.3390/biom12050695

Products & Services: Recombinant Antibody Expression

The recombinant defensin/HSA fusion protein that inhibits NF-κb associated with intensive macropinocytosis shows potent efficacy against pancreatic cancer

Authors: Yi-Bo Du, Xiao-Fei Wang, Xiu-Jun Liu, Yi Li, Qing-Fang Miao, Min Jiang, Wei-Jin Sheng, Yong-Su Zhen

Journal: Biochem Pharmacol

PubMed ID: 35489393

Doi: 10.1016/j.bcp.2022.115057

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Identifying Small-Molecule Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase by Establishing a Fluorometric Assay

Authors: Xiaoming Bai, Hongmin Sun, Shuo Wu, Yuhuan Li, Lifei Wang, Bin Hong

Journal: Front Immunol

PubMed ID: 35464436

Doi: 10.3389/fimmu.2022.844749

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Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation

Authors: Koen K A Van Rompay, Katherine J Olstad, Rebecca L Sammak, Joseph Dutra, Jennifer K Watanabe, Jodie L Usachenko, Ramya Immareddy, Jamin W Roh, Anil Verma, Yashavanth Shaan Lakshmanappa, Brian A Schmidt, Clara Di Germanio, Nabeela Rizvi, Hongwei Liu, Zhong-Min Ma, Mars Stone, Graham Simmons, Larry J Dumont, A Mark Allen, Sarah Lockwood, Rachel E Pollard, Rafael Ramiro de Assis, JoAnn L Yee, Peter B Nham, Amir Ardeshir, Jesse D Deere, Aarti Jain, Philip L Felgner, Lark L Coffey, Smita S Iyer, Dennis J Hartigan-O'Connor, Michael P Busch, J Rachel Reader

Journal: PLoS Pathog

PubMed ID: 35443018

Doi: 10.1371/journal.ppat.1009925

Products & Services: Recombinant Antibody Expression

A simple method to determine changes in the affinity between HisF and HisH in the Imidazole Glycerol Phosphate Synthase heterodimer

Authors: Vitor M Almeida, J Patrick Loria, Sandro R Marana

Journal: PLoS ONE

PubMed ID: 35452497

Doi: 10.1371/journal.pone.0267536

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Structure of SNX9 SH3 in complex with a viral ligand reveals the molecular basis of its unique specificity for alanine-containing class I SH3 motifs

Authors: Helena Tossavainen, Hasan Uğurlu, Mikael Karjalainen, Maarit Hellman, Lina Antenucci, Riku Fagerlund, Kalle Saksela, Perttu Permi