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Soluble N-terminal region of prion protein causes rapid neurodegeneration in prion disease

Authors: Runchuan Yan, Yan Zhang, Jingjing Zhang, Xiangyi Zhang, Yue Han, Mengfei Wang, Dan Wang, Shengnan Huang, Wei Liu, Qi Shi, Xiaoping Dong, Wen-Quan Zou, Zhen Li, Jiyan Ma

Journal: SCIENCE ADVANCES

PubMed ID: 40768577

Doi: 10.1126/sciadv.adw6867

Products & Services: Recombinant Antibody Expression

Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryo-EM

Authors: James A Ferguson, Sai Sundar Rajan Raghavan, Garazi Peña Alzua, Disha Bhavsar, Jiachen Huang, Alesandra J Rodriguez, Jonathan L Torres, Maria Bottermann, Julianna Han, Florian Krammer, Facundo D Batista, Andrew B Ward

Journal: SCIENCE ADVANCES

PubMed ID: 40815640

Doi: 10.1126/sciadv.adv8257

Products & Services: Recombinant Antibody Expression

HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates

Authors: Krystal M Ma, Henry J Sutton, Payal P Pratap, Jon M Steichen, Diane Carnathan, James Quinn, Oleksandr Kalyuzhniy, Alessia Liguori, Sashank Agrawal, Sabyasachi Baboo, Patrick Madden, Christopher A Cottrell, Jordan R Willis, Jeong-Hyun Lee, Elise Landais, Xiaozhen Hu, Parham Ramezani-Rad, Gabriel Ozorowski, Vanessa R Lewis, Jolene K Diedrich, Xiaoya Zhou, Tasha K Altheide, Nicole Phelps, Erik Georgeson, Nushin B Alavi, Danny Lu, Saman Eskandarzadeh, Michael Kubitz, Yumiko Adachi, Tina-Marie Mullen, Murillo Silva, Mariane B Melo, Sunny Himansu, Darrell J Irvine, Dennis R Burton, John R Yates 3rd, James C Paulson, Devin Sok, Ian A Wilson, Guido Silvestri, Andrew B Ward, Shane

Journal: Science immunology

PubMed ID: 40845127

Doi: 10.1126/sciimmunol.adt6660

Products & Services: Recombinant Antibody Expression

Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350

Authors: M Gordon Joyce, Wei Bu, Wei-Hung Chen, Rebecca A Gillespie, Sarah F Andrews, Adam K Wheatley, Yaroslav Tsybovsky, Jaime L Jensen, Tyler Stephens, Madhu Prabhakaran, Brian E Fisher, Sandeep R Narpala, Meghna Bagchi, Adrian B McDermott, Gary J Nabel, Peter D Kwong, John R Mascola, Jeffrey I Cohen, Masaru Kanekiyo

Journal: Immunity

PubMed ID: 39909035

Doi: 10.1016/j.immuni.2025.01.010

Products & Services: Recombinant Antibody Expression

The cryo-EM structure of homotetrameric attachment glycoprotein from langya henipavirus

Authors: Yingying Guo , Songyue Wu , Wenting Li , Haonan Yang , Tianhao Shi , Bin Ju , Zheng Zhang , Renhong Yan

Journal: Nat Commun

PubMed ID: 38280880

Doi: 10.1038/s41467-024-45202-5

Products & Services: Recombinant Antibody Expression

CGI1746 targets σ1R to modulate ferroptosis through mitochondria-associated membranes

Authors: Zili Zhang, Hong Zhou, Wenjia Gu, Yuehan Wei, Shan Mou, Youjun Wang, Jing Zhang & Qing Zhong

Journal: Nature Chemical Biology

PubMed ID: 38212578

Doi: 10.1038/s41589-023-01512-1

Products & Services: Recombinant Antibody Expression

IRGM is a novel regulator of PD-L1 via promoting S6K1-mediated phosphorylation of YBX1 in hepatocellular carcinoma

Authors: Junnan Ru, Jiahua Lu, Jiangzhen Ge, Bo Ding, Rong Su, Yifan Jiang, Yujing Sun, Jun Ma, Yu Li, Jingqi Sun, Guangming Xu, Rongliang Tong, Shusen Zheng, Beng Yang, Jian Wu

Journal: Cancer Lett

PubMed ID: 37993085

Doi: 10.1016/j.canlet.2023.216495

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Development of a plant-based oral vaccine candidate against the bovine respiratory pathogen

Authors: Angelo Kaldis, Muhammed Salah Uddin, Jose Ortiz Guluarte, Coby Martin, Trevor W Alexander, Rima Menassa

Journal: Front Plant Sci

PubMed ID: 37790785

Doi: 10.3389/fpls.2023.1251046

Products & Services: Recombinant Antibody Expression

Gonacin: A germ cell-derived hormone with glucogenic, orexigenic, and gonadal activities

Authors: Yixuan Hu, Shengyou Zhao, Zhiquan Liu, Tao Kang, Aaron J W Hsueh, Jianzhen Li