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The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors

Authors: Lucia Silvestrini, Norhan Belhaj, Lucia Comez, Yuri Gerelli, Antonino Lauria, Valeria Libera, Paolo Mariani, Paola Marzullo, Maria Grazia Ortore, Antonio Palumbo Piccionello, Caterina Petrillo, Lucrezia Savini, Alessandro Paciaroni, Francesco Spinozzi

Journal: Sci Rep

PubMed ID: 33927258

Doi: 10.1038/s41598-021-88630-9

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Diversity of Functionally Distinct Clonal Sets of Human Conventional Memory B Cells That Bind Staphylococcal Protein A

Authors: Emily E Radke, Zhi Li, David N Hernandez, Hanane El Bannoudi, Sergei L Kosakovsky Pond, Bo Shopsin, Peter Lopez, David Fenyö, Gregg J Silverman

Journal: Front Immunol

PubMed ID: 33995388

Doi: 10.3389/fimmu.2021.662782

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Lipid Nanoparticle-Mediated Lymphatic Delivery of Immunostimulatory Nucleic Acids

Authors: Dongyoon Kim, Yina Wu, Gayong Shim, Yu-Kyoung Oh

Journal: Pharmaceutics

PubMed ID: 33916667

Doi: 10.3390/pharmaceutics13040490

Products & Services: Recombinant Antibody Expression

The SARS-CoV-2 mRNA-1273 vaccine elicits more RBD-focused neutralization, but with broader antibody binding within the RBD

Authors: Allison J Greaney, Andrea N Loes, Lauren E Gentles, Katharine H D Crawford, Tyler N Starr, Keara D Malone, Helen Y Chu, Jesse D Bloom

Journal: biorxiv

PubMed ID: 33880474

Doi: 10.1101/2021.04.14.439844

Products & Services: Recombinant Antibody Expression

Lipid Nanoparticle-Mediated Lymphatic Delivery of Immunostimulatory Nucleic Acids

Authors: Dongyoon Kim, Yina Wu, Gayong Shim, Yu-Kyoung Oh

Journal: Pharmaceutics

PubMed ID: 33916667

Doi: 10.3390/pharmaceutics13040490

Products & Services: Recombinant Antibody Expression

Ehrlichia chaffeensis TRP120 Is a Wnt Ligand Mimetic That Interacts with Wnt Receptors and Contains a Novel Repetitive Short Linear Motif That Activates Wnt Signaling

Authors: Madison R Rogan, LaNisha L Patterson, Caitlan D Byerly, Tian Luo, Slobodan Paessler, Veljko Veljkovic, Bethany Quade, Jere W McBride

Journal: mSphere

PubMed ID: 33883266

Doi: 10.1128/mSphere.00216-21

Products & Services: Recombinant Antibody Expression

A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

Authors: Alexandra Tauzin, Manon Nayrac, Mehdi Benlarbi, Shang Yu Gong, Romain Gasser, Guillaume Beaudoin-Bussières, Nathalie Brassard, Annemarie Laumaea, Dani Vézina, Jérémie Prévost, Sai Priya Anand, Catherine Bourassa, Gabrielle Gendron-Lepage, Halima Medjahed, Guillaume Goyette, Julia Niessl, Olivier Tastet, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Leonidas Stamatatos, Andrew T McGuire, Catherine Larochelle, Pradeep Uchil, Maolin Lu, Walther Mothes, Gaston De Serres, Sandrine Moreira, Michel Roger, Jonathan Richard, Valérie Martel-Laferrière, Ralf Duerr, Cécile Tremblay, Daniel E Kaufmann, Andrés Finzi

Journal: biorxiv

PubMed ID: 33758857

Doi: 10.1101/2021.03.18.435972

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Safflower Seed Extract Attenuates the Development of Osteoarthritis by Blocking NF-κB Signaling

Authors: Seong Jae Han, Min Ju Lim, Kwang Min Lee, Eunjeong Oh, Yu Su Shin, Seokho Kim, Joong Sun Kim, Seung Pil Yun, Li-Jung Kang

Journal: Pharmaceuticals (Basel)

PubMed ID: 33809253

Doi: 10.3390/ph14030258

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Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate

Authors: Wen-Hsiang Chen, Junfei Wei, Rakhi Tyagi Kundu, Rakesh Adhikari, Zhuyun Liu, Jungsoon Lee, Leroy Versteeg, Cristina Poveda, Brian Keegan, Maria Jose Villar, Ana C de Araujo Leao, Joanne Altieri Rivera, Portia M Gillespie, Jeroen Pollet, Ulrich Strych, Bin Zhan, Peter J Hotez, Maria Elena Bottazzi

Journal: Biochim Biophys Acta Gen Subj

PubMed ID: 33731300

Doi: 10.1016/j.bbagen.2021.129893

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Sialoglycan recognition is a common connection linking acidosis, zinc, and HMGB1 in sepsis

Authors: Shoib S Siddiqui, Chirag Dhar, Venkatasubramaniam Sundaramurthy, Aniruddha Sasmal, Hai Yu, Esther Bandala-Sanchez, Miaomiao Li, Xiaoxiao Zhang, Xi Chen, Leonard C Harrison, Ding Xu, Ajit Varki

Journal: Proc Natl Acad Sci U S A

PubMed ID: 33658363

Doi: 10.1073/pnas.2018090118

Products & Services: Recombinant Antibody Expression