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Immune Responses to a Single Dose of the AZD1222/Covishield Vaccine at 16 Weeks in Individuals in Sri Lanka

Authors: Chandima Jeewandara, Dinuka Guruge, Pradeep Darshana Pushpakumara, Achala Kamaladasa, Inoka Sepali Aberathna, Shyrar Tanussiya Ramu, Banuri Gunasekera, Ayesha Wijesinghe, Osanda Dissanayake, Heshan Kuruppu, Thushali Ranasinghe, Deshni Jayathilaka, Shashika Dayarathna, Dinithi Ekanayake, Jeewantha Jayamali, Nayanathara Gamalath, Anushika Mudunkotiwa, Gayasha Somathilake, Madhushika Dissanayake, Michael Harvie, Thashmi Nimasha, Deshan Madusanka, Tibutius Jayadas, Ruwan Wijayamuni, Lisa Schimanski, Pramila Rijal, Tiong K Tan, Alain Townsend, Graham S Ogg, Gathsaurie Neelika Malavige

Journal: J Immunol

PubMed ID: 34750205

Doi: 10.4049/jimmunol.2100762

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Using Continuous Directed Evolution to Improve Enzymes for Plant Applications

Authors: Jorge D García-García, Kristen Van Gelder, Jaya Joshi, Ulschan Bathe, Bryan J Leong, Steven D Bruner, Chang C Liu, Andrew D Hanson

Journal: Plant Physiol

PubMed ID: 34718794

Doi: 10.1093/plphys/kiab500

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Polymersomes as Stable Nanocarriers for a Highly Immunogenic and Durable SARS-CoV-2 Spike Protein Subunit Vaccine

Authors: Jian Hang Lam, Amit K Khan, Thomas A Cornell, Teck Wan Chia, Regine J Dress, Wen Wang William Yeow, Nur Khairiah Mohd-Ismail, Shrinivas Venkataraman, Kim Tien Ng, Yee-Joo Tan, Danielle E Anderson, Florent Ginhoux, Madhavan Nallani

Journal: ACS Nano

PubMed ID: 34618423

Doi: 10.1021/acsnano.1c01243

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Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern

Authors: Hyeseon Cho, Kristina Kay Gonzales-Wartz, Deli Huang, Meng Yuan, Mary Peterson, Janie Liang, Nathan Beutler, Jonathan L Torres, Yu Cong, Elena Postnikova, Sandhya Bangaru, Chloe Adrienna Talana, Wei Shi, Eun Sung Yang, Yi Zhang, Kwanyee Leung, Lingshu Wang, Linghang Peng, Jeff Skinner, Shanping Li, Nicholas C Wu, Hejun Liu, Cherrelle Dacon, Thomas Moyer, Melanie Cohen, Ming Zhao, Frances Eun-Hyung Lee, Rona S Weinberg, Iyadh Douagi, Robin Gross, Connie Schmaljohn, Amarendra Pegu, John R Mascola, Michael Holbrook, David Nemazee, Thomas F Rogers, Andrew B Ward, Ian A Wilson, Peter D Crompton, Joshua Tan

Journal: Sci Transl Med

PubMed ID: 34519517

Doi: 10.1126/scitranslmed.abj5413

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TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Transition of Microglia and Formation of Neutrophil Extracellular Traps Interaction With SYK in Experimental Subarachnoid Hemorrhage

Authors: Xinyan Wu, Hanhai Zeng, Chaoran Xu, Huaijun Chen, Linfeng Fan, Hang Zhou, Qian Yu, Xiongjie Fu, Yucong Peng, Feng Yan, Xiaobo Yu, Gao Chen

Journal: Front Immunol

PubMed ID: 34721438

Doi: 10.3389/fimmu.2021.766178

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Characterization of the genetic switch from phage ɸ13 important for Staphylococcus aureus colonization in humans

Authors: Camilla S Kristensen, Anders K Varming, Helena A K Leinweber, Karin Hammer, Leila Lo Leggio, Hanne Ingmer, Mogens Kilstrup

Journal: Microbiologyopen

PubMed ID: 34713608

Doi: 10.1002/mbo3.1245

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VpreB Surrogate Light Chain Expression in B-Lineage ALL: A Report from the Children's Oncology Group

Authors: Stuart Sheldon Winter, Amanda McCaustland, Chunxu Qu, No'eau Simeona, Nyla A Heerema, Andrew J Carroll, Brent L Wood, Gabriela Gheorghe, Charles G Mullighan, Bridget S Wilson

Journal: Blood Adv

PubMed ID: 34662891

Doi: 10.1182/bloodadvances.2021005245

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Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma

Authors: Sakiko Harada, Miki Ando, Jun Ando, Midori Ishii, Tomoyuki Yamaguchi, Satoshi Yamazaki, Tokuko Toyota, Kazuo Ohara, Manami Ohtaka, Mahito Nakanishi, Chansu Shin, Yasunori Ota, Kazutaka Nakashima, Koichi Ohshima, Chihaya Imai, Yozo Nakazawa, Hiromitsu Nakauchi, Norio Komatsu

Journal: Mol Ther

PubMed ID: 34628050

Doi: 10.1016/j.ymthe.2021.10.006

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Hinge influences in murine IgG binding to Cryptococcus neoformans capsule

Authors: Diane Sthefany Lima de Oliveira, Verenice Paredes, Adrielle Veloso Caixeta, Nicole Moreira Henriques, Maggie P Wear, Patrícia Albuquerque, Maria Sueli Soares Felipe, Arturo Casadevall, André Moraes Nicola

Journal: Immunology

PubMed ID: 34458991

Doi: 10.1111/imm.13411

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Multiplexed analysis of small extracellular vesicle-derived mRNAs by droplet digital PCR and machine learning improves breast cancer diagnosis

Authors: Chunchen Liu, Bo Li, Huixian Lin, Chao Yang, Jingyun Guo, Binbin Cui, Weilun Pan, Junjie Feng, Tingting Luo, Fuxin Chu, Xiaonan Xu, Lei Zheng, Shuhuai Yao

Journal: Biosens Bioelectron

PubMed ID: 34507095

Doi: 10.1016/j.bios.2021.113615

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