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Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer

Authors: Liu X, Bao X, Hu M, Chang H, Jiao M, Cheng J, Xie L, Huang Q, Li F, Li CY

Journal: Nature

PubMed ID: 33177715

Doi: 10.1038/s41586-020-2911-7

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KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies

Authors: Pablo Ávalos Prado, Stephanie Häfner, Yannick Comoglio, Brigitte Wdziekonski, Christophe Duranton, Bernard Attali, Jacques Barhanin, Guillaume Sandoz

Journal: Cell

PubMed ID: 33373586

Doi: 10.1016/j.cell.2020.11.047

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Autocrine IL-6/STAT3 signaling aids development of acquired drug resistance in Group 3 medulloblastoma

Authors: Sreenivasan L, Wang H, Yap SQ, Leclair P, Tam A, Lim CJ

Journal: Cell death & disease

PubMed ID: 33279931

Doi: 10.1038/s41419-020-03241-y

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Mas Receptor Activation Contributes to the Improvement of Nitric Oxide Bioavailability and Vascular Remodeling During Chronic AT1R (Angiotensin Type-1 Receptor) Blockade in Experimental Hypertension

Authors: Savoia C, Arrabito E, Parente R, Nicoletti C, Madaro L, Battistoni A, Filippini A, Steckelings UM, Touyz RM, Volpe M

Journal: Hypertension (Dallas, Tex. : 1979)

PubMed ID: 33070664

Doi: 10.1161/HYPERTENSIONAHA.120.15527

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Retro-inverso D-peptides as a novel targeted immunotherapy for Type 1 diabetes

Authors: Lombardi A, Concepcion E, Hou H, Arib H, Mezei M, Osman R, Tomer Y

Journal: Journal of autoimmunity

PubMed ID: 32951964

Doi: 10.1016/j.jaut.2020.102543

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B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms

Authors: Watanabe M,Lu Y,Breen M,Hodes RJ

Journal: Nature Communications

PubMed ID: 33293517

Doi: 10.1038/s41467-020-20070-x

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Elevated ectodomain of type 23 collagen is a novel biomarker of the intestinal epithelium to monitor disease activity in ulcerative colitis and Crohn's disease

Authors: T Manon-Jensen, S Sun, M Lindholm, V Domislović, P Giuffrida, M Brinar, G Mazza, M Pinzani, Ž Krznarić, A Di Sabatino, M A Karsdal, J H Mortensen

Journal: United European Gastroenterol J

PubMed ID: 33351719

Doi: 10.1177/2050640620977371

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An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline

Authors: Trzeciakiewicz H, Ajit D, Tseng JH, Chen Y, Ajit A, Tabassum Z, Lobrovich R, Peterson C, Riddick NV, Itano MS, Tripathy A, Moy SS, Lee VMY, Trojanowski JQ, Irwin DJ, Cohen TJ

Journal: Nature Communications

PubMed ID: 33139698

Doi: 10.1038/s41467-020-19317-4

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PPARα Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates

Authors: Kamata S,Oyama T,Saito K,Honda A,Yamamoto Y,Suda K,Ishikawa R,Itoh T,Watanabe Y,Shibata T,Uchida K,Suematsu M,Ishii I

Journal: iScience

PubMed ID: 33205029

Doi: 10.1016/j.isci.2020.101727

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Multiple Sclerosis-Like Symptoms in Mice Are Driven by Latent γHerpesvirus-68 Infected B Cells

Authors: Ana Citlali Márquez, Iryna Shanina, Marc Steven Horwitz

Journal: Front Immunol

PubMed ID: 33329556

Doi: 10.3389/fimmu.2020.584297

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