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A conjoined universal helper epitope can unveil antitumor effects of a neoantigen vaccine targeting an MHC class I-restricted neoepitope
Authors: Adam M Swartz, Kendra L Congdon, Smita K Nair, Qi-Jing Li, James E Herndon, Carter M Suryadevara, Katherine A Riccione, Gary E Archer, Pamela K Norberg, Luis A Sanchez-Perez, John H Sampson
Journal: npj Vaccines
PubMed ID: 33462231
Doi: 10.1038/s41541-020-00273-5
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A binding protein regulates myosin-7a dimerization and actin bundle assembly
Authors: Rong Liu, Neil Billington, Yi Yang, Charles Bond, Amy Hong, Verl Siththanandan, Yasuharu Takagi, James R Sellers
Journal: Nat Commun
PubMed ID: 33495456
Doi: 10.1038/s41467-020-20864-z
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The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks
Authors: Ann-Marie K Shorrocks, Samuel E Jones, Kaima Tsukada, Carl A Morrow, Zoulikha Belblidia, Johanna Shen, Iolanda Vendrell, Roman Fischer, Benedikt M Kessler, Andrew N Blackford
Journal: Nat Commun
PubMed ID: 33500419
Doi: 10.1038/s41467-020-20818-5
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Design of a PEGylated Antimicrobial Prodrug with Species-Specific Activation
Authors: Meghan K O'Leary, Sabrina S Chen, Lars F Westblade, Christopher A Alabi
Journal: Biomacromolecules
PubMed ID: 33428376
Doi: 10.1021/acs.biomac.0c01695
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Laboratory evolution of a sortase enzyme that modifies amyloid-β protein
Authors: Christopher J Podracky, Chihui An, Alexandra DeSousa, Brent M Dorr, Dominic M Walsh, David R Liu
Journal: Nat Chem Biol
PubMed ID: 33432237
Doi: 10.1038/s41589-020-00706-1
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Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization
Authors: Franziska Mueller, Alexandra Friese, Claudio Pathe, Richard Cardoso da Silva, Kenny Bravo Rodriguez, Andrea Musacchio, Tanja Bange
Journal: Sci Adv
PubMed ID: 33523899
Doi: 10.1126/sciadv.abc8590
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Peptide-Spectrum Match Validation with Internal Standards (P-VIS): Internally-Controlled Validation of Mass Spectrometry-Based Peptide Identifications
Authors: Wiles TA, Saba LM, Delong T
Journal: Journal of proteome research
PubMed ID: 32924495
Doi: 10.1021/acs.jproteome.0c00355
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Corals regulate the distribution and abundance of Symbiodiniaceae and biomolecules in response to changing water depth and sea surface temperature
Authors: Mayandi Sivaguru, Lauren G Todorov, Courtney E Fouke, Cara M O Munro, Kyle W Fouke, Kaitlyn E Fouke, Melinda E Baughman, Bruce W Fouke
Journal: Sci Rep
PubMed ID: 33500473
Doi: 10.1038/s41598-021-81520-0
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Short peptides as predictors for the structure of polyarginine sequences in disordered proteins
Authors: Bridget Milorey, Reinhard Schweitzer-Stenner, Brian Andrews, Harald Schwalbe, Brigita Urbanc
Journal: Biophys J
PubMed ID: 33453267
Doi: 10.1016/j.bpj.2020.12.026
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Generation of Highly Selective, Potent, and Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors
Authors: Rachel A Rowlands, Qiuyan Chen, Renee A Bouley, Larisa V Avramova, John J G Tesmer, Andrew D White
Journal: J Med Chem
PubMed ID: 33393767
Doi: 10.1021/acs.jmedchem.0c01522
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