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Tumor-reactive antibodies evolve from non-binding and autoreactive precursors

Authors: Roei D Mazor, Nachum Nathan, Amit Gilboa, Liat Stoler-Barak, Lihee Moss, Inna Solomonov, Assaf Hanuna, Yalin Divinsky, Merav D Shmueli, Hadas Hezroni, Irina Zaretsky, Michael Mor, Ofra Golani, Gad Sabah, Ariella Jakobson-Setton, Natalia Yanichkin, Meora Feinmesser, Daliah Tsoref, Lina Salman, Effi Yeoshoua, Eyal Peretz, Inna Erlich, Netta Mendelson Cohen, Jonathan M Gershoni, Natalia Freund, Yifat Merbl, Gur Yaari, Ram Eitan, Irit Sagi, Ziv Shulman

Journal: Cell

PubMed ID: 35305314

Doi: 10.1016/j.cell.2022.02.012

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Genome-wide investigation of maize RAD51 binding affinity through phage display

Authors: Claire Milsted, Bo Dai, Nelson Garcia, Lu Yin, Yan He, Shahryar Kianian, Wojciech Pawlowski, Changbin Chen

Journal: BMC Genomics

PubMed ID: 35279087

Doi: 10.1186/s12864-022-08419-6

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Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate

Authors: Ian Seim, Ammon E Posey, Wilton T Snead, Benjamin M Stormo, Daphne Klotsa, Rohit V Pappu, Amy S Gladfelter

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35333653

Doi: 10.1073/pnas.2120799119

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Determination of T Cell Responses in Thai Systemic Sclerosis Patients

Authors: Oranit Likhit, Worawit Louthrenoo, Sa-Nga Pattanakitsakul, Aroonroong Suttitheptumrong, Supot Hannongbua, Thanyada Rungrotmongkol, Hiroshi Noguchi, Fujio Takeuchi, Kobporn Boonnak

Journal: J Immunol Res

PubMed ID: 35310606

Doi: 10.1155/2022/5072154

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Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy

Authors: Songfa Zhang, Chuan Yan, David G Millar, Qiqi Yang, James M Heather, Adam Langenbucher, Laura T Morton, Sean Sepulveda, Eric Alpert, Lauren R Whelton, Dominique T Zarrella, Mei Guo, Eleanor Minogue, Michael S Lawrence, Bo R Rueda, David R Spriggs, Weiguo Lu, David M Langenau, Mark Cobbold

Journal: Cancer Res

PubMed ID: 34965933

Doi: 10.1158/0008-5472.CAN-21-2200

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Resveratrol Blunts Mitochondrial Loss in Slow and Mixed Skeletal Muscle Phenotypes of Non-Human Primates following a Long-Term High Fat/Sugar Diet

Authors: Jon-Philippe K Hyatt, Rafael de Cabo, Julie A Mattison

Journal: J Diet Suppl

PubMed ID: 35229700

Doi: 10.1080/19390211.2022.2039340

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HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people

Authors: Jennifer R Habel, Andrea T Nguyen, Louise C Rowntree, Christopher Szeto, Nicole A Mifsud, E Bridie Clemens, Liyen Loh, Weisan Chen, Steve Rockman, Jane Nelson, Jane Davies, Adrian Miller, Steven Y C Tong, Jamie Rossjohn, Stephanie Gras, Anthony W Purcell, Luca Hensen, Katherine Kedzierska, Patricia T Illing

Journal: PLoS Pathog

PubMed ID: 35255101

Doi: 10.1371/journal.ppat.1010337

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DNA methylation in Friedreich ataxia silences expression of frataxin isoform E

Authors: Layne N Rodden, Kaitlyn M Gilliam, Christina Lam, Teerapat Rojsajjakul, Clementina Mesaros, Chiara Dionisi, Mark Pook, Massimo Pandolfo, David R Lynch, Ian A Blair, Sanjay I Bidichandani

Journal: Sci Rep

PubMed ID: 35322126

Doi: 10.1038/s41598-022-09002-5

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Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals

Authors: Zi-Wei Ye, Chon Phin Ong, Kaiming Tang, Yilan Fan, Cuiting Luo, Runhong Zhou, Peng Luo, Yun Cheng, Victor Sebastien Gray, Pui Wang, Hin Chu, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Honglin Chen, Zhiwei Chen, Kwok-Yung Yuen, Guang Sheng Ling, Shuofeng Yuan, Dong-Yan Jin

Journal: Cell Mol Immunol

PubMed ID: 35352010

Doi: 10.1038/s41423-022-00855-4

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Aquaporin OsPIP2;2 links the H2O2 signal and a membrane-anchored transcription factor to promote plant defense

Authors: Mou Zhang, Haotian Shi, Ningning Li, Nana Wei, Yan Tian, Jinfeng Peng, Xiaochen Chen, Liyuan Zhang, Meixiang Zhang, Hansong Dong

Journal: Plant Physiol

PubMed ID: 34958388

Doi: 10.1093/plphys/kiab604

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