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Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis
Authors: Do Hoon Kwon, Feng Zhang, Justin G Fedor, Yang Suo, Seok-Yong Lee
Journal: Nat Commun
PubMed ID: 35610228
Doi: 10.1038/s41467-022-30602-2
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Rgs16 promotes antitumor CD8 T cell exhaustion
Authors: Nina Weisshaar, Jingxia Wu, Yanan Ming, Alaa Madi, Agnes Hotz-Wagenblatt, Sicong Ma, Alessa Mieg, Marvin Hering, Ferdinand Zettl, Kerstin Mohr, Tilo Schlimbach, Nora Ten Bosch, Franziska Hertel, Lisann Müller, Hannah Byren, Mona Wang, Helena Borgers, Mareike Munz, Lukas Schmitt, Franciscus van der Hoeven, Ulrich Kloz, Rafael Carretero, Nikolai Schleußner, Rene-Filip Jackstadt, Ilse Hofmann, Guoliang Cui
Journal: Sci Immunol
PubMed ID: 35622904
Doi: 10.1126/sciimmunol.abh1873
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Engineered SH2 Domains for Targeted Phosphoproteomics
Authors: Gregory D Martyn, Gianluca Veggiani, Ulrike Kusebauch, Seamus R Morrone, Bradley P Yates, Alex U Singer, Jiefei Tong, Noah Manczyk, Gerald Gish, Zhi Sun, Igor Kurinov, Frank Sicheri, Michael F Moran, Robert L Moritz, Sachdev S Sidhu
Journal: ACS Chem Biol
PubMed ID: 35613471
Doi: 10.1021/acschembio.2c00051
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A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2
Authors: Junyu Chen, Pui Wang, Lunzhi Yuan, Liang Zhang, Limin Zhang, Hui Zhao, Congjie Chen, Xijing Wang, Jinle Han, Yaode Chen, Jizong Jia, Zhen Lu, Junping Hong, Zicen Lu, Qian Wang, Rirong Chen, Ruoyao Qi, Jian Ma, Min Zhou, Huan Yu, Chunlan Zhuang, Xiaohui Liu, Qiangyuan Han, Guosong Wang, Yingying Su, Quan Yuan, Tong Cheng, Ting Wu, Xiangzhong Ye, Tianying Zhang, Changgui Li, Jun Zhang, Huachen Zhu, Yixin Chen, Honglin Chen, Ningshao Xia
Journal: Sci Bull (Beijing)
PubMed ID: 35637645
Doi: 10.1016/j.scib.2022.05.018
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Rad51-mediated replication of damaged templates relies on monoSUMOylated DDK kinase
Authors: Chinnu Rose Joseph, Sabrina Dusi, Michele Giannattasio, Dana Branzei
Journal: Nat Commun
PubMed ID: 35513396
Doi: 10.1038/s41467-022-30215-9
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Durable immunogenicity, adaptation to emerging variants, and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques
Authors: Nerea Zabaleta, Urja Bhatt, Cécile Hérate, Pauline Maisonnasse, Julio Sanmiguel, Cheikh Diop, Sofia Castore, Reynette Estelien, Dan Li, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Quentin Pascal, Thibaut Naninck, Nidhal Kahlaoui, Julien Lemaitre, Francis Relouzat, Giuseppe Ronzitti, Hendrik Jan Thibaut, Emanuele Montomoli, James M Wilson, Roger Le Grand, Luk H Vandenberghe
Journal: Mol Ther
PubMed ID: 35546782
Doi: 10.1016/j.ymthe.2022.05.007
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Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis
Authors: Andy Weiss, Caitlin C Murdoch, Katherine A Edmonds, Matthew R Jordan, Andrew J Monteith, Yasiru R Perera, Aslin M Rodríguez Nassif, Amber M Petoletti, William N Beavers, Matthew J Munneke, Sydney L Drury, Evan S Krystofiak, Kishore Thalluri, Hongwei Wu, Angela R S Kruse, Richard D DiMarchi, Richard M Caprioli, Jeffrey M Spraggins, Walter J Chazin, David P Giedroc, Eric P Skaar
Journal: Cell
PubMed ID: 35584702
Doi: 10.1016/j.cell.2022.04.011
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Electrochemical biosensor for rapid detection of fungal contamination in fuel systems
Authors: Osman Radwan, Michael C Brothers, Victoria Coyle, Molly E Chapleau, Richard R Chapleau, Steve S Kim, Oscar N Ruiz
Journal: Biosens Bioelectron
PubMed ID: 35605548
Doi: 10.1016/j.bios.2022.114374
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Knockout Alleviates DSS-Induced Colitis Regulating the Immune Function of Dendritic Cells
Authors: Wei Wei, Sucheng Mu, Yi Han, Yao Chen, Zhongshu Kuang, Xingyue Wu, Yue Luo, Chaoyang Tong, Yiqun Zhang, Yilin Yang, Zhenju Song
Journal: Front Immunol
PubMed ID: 35669778
Doi: 10.3389/fimmu.2022.841254
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A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice
Authors: Liqin Liu, Tingting Chen, Lizhi Zhou, Jie Sun, Yuqian Li, Meifeng Nie, Hualong Xiong, Yuhe Zhu, Wenhui Xue, Yangtao Wu, Tingting Li, Tianying Zhang, Zhibo Kong, Hai Yu, Jun Zhang, Ying Gu, Qingbing Zheng, Qinjian Zhao, Ningshao Xia, Shaowei Li
Journal: Front Microbiol
PubMed ID: 35558112
Doi: 10.3389/fmicb.2022.854630
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