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Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer's disease by inhibiting neuroinflammation and neuronal necroptosis
Authors: Chong Xu, Yilan Mei, Ruihan Yang, Qiudan Luo, Jienian Zhang, Xiaolin Kou, Jianfeng Hu, Yujie Wang, Yue Li, Rong Chen, Zhengping Zhang, Yuyuan Yao, Jian Sima
Journal: Cell Biosci
PubMed ID: 38678262
Doi: 10.1186/s13578-024-01230-8
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The Bifunctional Effects of Lactoferrin (LFcinB11) in Inhibiting Neural Cell Adhesive Molecule (NCAM) Polysialylation and the Release of Neutrophil Extracellular Traps (NETs)
Authors: Bo Lu, Si-Ming Liao, Shi-Jie Liang, Li-Xin Peng, Jian-Xiu Li, Xue-Hui Liu, Ri-Bo Huang, Guo-Ping Zhou
Journal: Int J Mol Sci
PubMed ID: 38731861
Doi: 10.3390/ijms25094641
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Regulation by the RNA-binding protein Unkempt at its effector interface
Authors: Kriti Shah, Shiyang He, David J Turner, Joshua Corbo, Khadija Rebbani, Daniel Dominguez, Joseph M Bateman, Sihem Cheloufi, Cátia Igreja, Eugene Valkov, Jernej Murn
Journal: Nat Commun
PubMed ID: 38605040
Doi: 10.1038/s41467-024-47449-4
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Developing Plant Exosomes as an Advanced Delivery System for Cosmetic Peptide
Authors: Jiali Hou, Wei Wei, Zaijun Geng, Zhenxing Zhang, Hui Yang, Xuhui Zhang, Li Li, Qi Gao
Journal: ACS Appl Bio Mater
PubMed ID: 38598772
Doi: 10.1021/acsabm.4c00096
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Gene replacement therapy in Bietti crystalline corneoretinal dystrophy: an open-label, single-arm, exploratory trial
Authors: Jinyuan Wang, Jinlu Zhang, Shicheng Yu, Hongyan Li, Shaohong Chen, Jingting Luo, Haibo Wang, Yuxia Guan, Haihan Zhang, Shiyi Yin, Huili Wang, Heping Li, Junle Liu, Jingyuan Zhu, Qiong Yang, Ying Sha, Chuan Zhang, Yuhang Yang, Xuan Yang, Xifang Zhang, Xiuli Zhao, Likun Wang, Liping Yang, Wenbin Wei
Journal: Signal Transduct Target Ther
PubMed ID: 38653979
Doi: 10.1038/s41392-024-01806-3
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Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both and
Authors: Qi-Xuan Huang, Da-Meng Fan, Zao-Zao Zheng, Ting Ran, Ao Bai, Rong-Quan Xiao, Guo-Sheng Hu, Wen Liu
Journal: J Med Chem
PubMed ID: 38569135
Doi: 10.1021/acs.jmedchem.4c00141
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Transcriptome analysis reveals the mechanism of antifungal peptide epinecidin-1 against Botrytis cinerea by mitochondrial dysfunction and oxidative stress
Authors: Li Fan, Yingying Wei, Yi Chen, Meriem Ouaziz, Shu Jiang, Feng Xu, Hongfei Wang, Xingfeng Shao
Journal: Pestic Biochem Physiol
PubMed ID: 38879298
Doi: 10.1016/j.pestbp.2024.105932
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Deciphering S100B Allosteric Signaling: The Role of a Peptide Target, TRTK-12, as an Ensemble Modulator
Authors: Riya Samanta, Xinhao Zhuang, Kristen M Varney, David J Weber, Silvina Matysiak
Journal: J Chem Inf Model
PubMed ID: 38605537
Doi: 10.1021/acs.jcim.4c00116
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A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: protection of African green monkeys from COVID-19 disease
Authors: Sham Nambulli, Nicolas Escriou, Linda J Rennick, Matthew J Demers, Natasha L Tilston-Lunel, Anita K McElroy, Dominique J Barbeau, Nicholas A Crossland, Ryan M Hoehl, Sabrina Schrauf, Alexander G White, H Jacob Borish, Jaime A Tomko, Lonnie J Frye, Charles A Scanga, JoAnne L Flynn, Annette Martin, Christiane Gerke, Amy L Hartman, W Paul Duprex
Journal: J Virol
PubMed ID: 38563762
Doi: 10.1128/jvi.01762-23
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Antibacterial and Hemolytic Activity of Antimicrobial Hydrogels Utilizing Immobilized Antimicrobial Peptides
Authors: Edvin Blomstrand, Elin Posch, Annija Stepulane, Anand K Rajasekharan, Martin Andersson
Journal: Int J Mol Sci
PubMed ID: 38673786
Doi: 10.3390/ijms25084200
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