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CRKL is a critical target of Hh-GLI2 pathway in lung adenocarcinoma

Authors: Xiaoming Liu, Yan Hu, Bentong Yu, Kai Peng, Xin Gan

Journal: J Cell Mol Med

PubMed ID: 34076957

Doi: 10.1111/jcmm.16592

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A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis

Authors: Shiqiang Hou, Gengming Niu, Xin Liu, Pierre M Bourbon, Dongmei Zhang, Pengfei Cui, Kevin Zhao, Dezheng Zhao, Huiyan Zeng

Journal: Microvasc Res

PubMed ID: 34146582

Doi: 10.1016/j.mvr.2021.104209

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Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design

Authors: Daniel Ellis, Natalie Brunette, Katharine H D Crawford, Alexandra C Walls, Minh N Pham, Chengbo Chen, Karla-Luise Herpoldt, Brooke Fiala, Michael Murphy, Deleah Pettie, John C Kraft, Keara D Malone, Mary Jane Navarro, Cassandra Ogohara, Elizabeth Kepl, Rashmi Ravichandran, Claire Sydeman, Maggie Ahlrichs, Max Johnson, Alyssa Blackstone, Lauren Carter, Tyler N Starr, Allison J Greaney, Kelly K Lee, David Veesler, Jesse D Bloom, Neil P King

Journal: Front Immunol

PubMed ID: 34267764

Doi: 10.3389/fimmu.2021.710263

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Impact of Membrane Lipids on UapA and AzgA Transporter Subcellular Localization and Activity in

Authors: Mariangela Dionysopoulou, George Diallinas

Journal: J Fungi (Basel)

PubMed ID: 34203131

Doi: 10.3390/jof7070514

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SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

Authors: Clemens Gutmann, Kaloyan Takov, Sean A Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark Jw McPhail, Kevin O'Gallagher, Lukas E Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernández-Leiro, Silke Braun, Romy Kronstein-Wiedemann, Katie J Doores, Jonathan D Edgeworth, Ajay M Shah, Stefan R Bornstein, Torsten Tonn, Adrian C Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr

Journal: Nat Commun

PubMed ID: 34099652

Doi: 10.1038/s41467-021-23494-1

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Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn

Authors: David Sychantha, Caitlyn M Rotondo, Kamaleddin H M E Tehrani, Nathaniel I Martin, Gerard D Wright

Journal: J Biol Chem

PubMed ID: 34181945

Doi: 10.1016/j.jbc.2021.100918

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SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms

Authors: Christine Vazquez, Sydnie E Swanson, Seble G Negatu, Mark Dittmar, Jesse Miller, Holly R Ramage, Sara Cherry, Kellie A Jurado

Journal: PLoS ONE

PubMed ID: 34166398

Doi: 10.1371/journal.pone.0253089

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The E3 ligase XBAT35 mediates thermoresponsive hypocotyl growth by targeting ELF3 for degradation in Arabidopsis

Authors: Lin-Lin Zhang, Wei Li , Ying-Ying Tian, Seth Jon Davis, Jian-Xiang Liu

Journal: J Integr Plant Biol

PubMed ID: 33963671

Doi: 10.1111/jipb.13107

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Glutaminolysis is involved in the activation of mTORC1 in in vitro-produced porcine embryos

Authors: Paula R Chen, Caroline G Lucas, Lee D Spate, Randall S Prather

Journal: Mol Reprod Dev

PubMed ID: 34075648

Doi: 10.1002/mrd.23516

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Silencing of ANGPTL8 Alleviates Insulin Resistance in Trophoblast Cells

Authors: Yu Bai, Qiang Du, Le Zhang, Ling Li, Nana Wang, Bo Wu, Ping Li, Ling Li

Journal: Front Endocrinol (Lausanne)

PubMed ID: 34163433

Doi: 10.3389/fendo.2021.635321

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