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SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques

Authors: Carolina Garrido, Alan D Curtis, Maria Dennis, Sachi H Pathak, Hongmei Gao, David Montefiori, Mark Tomai, Christopher B Fox, Pamela A Kozlowski, Trevor Scobey, Jennifer E Munt, Michael L Mallory, Pooja T Saha, Michael G Hudgens, Lisa C Lindesmith, Ralph S Baric, Olubukola M Abiona, Barney Graham, Kizzmekia S Corbett, Darin Edwards, Andrea Carfi, Genevieve Fouda, Koen K A Van Rompay, Kristina De Paris, Sallie R Permar

Journal: Sci Immunol

PubMed ID: 34131024

Doi: 10.1126/sciimmunol.abj3684

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Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX

Authors: Jiajia Ma, Claire A Scott, Ying Na Ho, Harsha Mahabaleshwar, Katherine S Marsay, Changqing Zhang, Christopher Kj Teow, Ser Sue Ng, Weibin Zhang, Vinay Tergaonkar, Lynda J Partridge, Sudipto Roy, Enrique Amaya, Tom J Carney

Journal: Elife

PubMed ID: 34165081

Doi: 10.7554/eLife.66596

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Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y₁₂ signaling pathway

Authors: Huang B, Qian Y, Xie S, Ye X, Chen H, Chen Z, Zhang L, Xu J, Hu H, Ma S, Héroux P, Wang D, Shen HM, Wu Y, Xia D

Journal: Cellular & molecular immunology

PubMed ID: 32523112

Doi: 10.1038/s41423-020-0444-5

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Porcine circovirus type 2 infection attenuates the K63-linked ubiquitination of STING to inhibit IFN-β induction via p38-MAPK pathway

Authors: Xingchen Wu, Zhenyu Wang, Dan Qiao, Yu Yuan, Cong Han, Nan Yang, Ruizhen Li, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 33984793

Doi: 10.1016/j.vetmic.2021.109098

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A Dynamic, Ring-Forming Bactofilin Critical for Maintaining Cell Size in the Obligate Intracellular Bacterium

Authors: Mary R Brockett, Junghoon Lee, John V Cox, George W Liechti, Scot P Ouellette

Journal: Infect Immun

PubMed ID: 33941579

Doi: 10.1128/IAI.00203-21

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Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering

Authors: Nicolas O Jørgensen, Rasmus Kjøbsted, Magnus R Larsen, Jesper B Birk, Nicoline R Andersen, Bina Albuquerque, Peter Schjerling, Russell Miller, David Carling, Christian K Pehmøller, Jørgen F P Wojtaszewski

Journal: Mol Metab

PubMed ID: 34033941

Doi: 10.1016/j.molmet.2021.101259

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The aminosterol Claramine inhibits β-secretase 1-mediated insulin receptor cleavage

Authors: Bénédicte Gaborit, Roland Govers, Alexandre Altié, Jean Michel Brunel, Pierre Morange, Franck Peiretti

Journal: J Biol Chem

PubMed ID: 34029592

Doi: 10.1016/j.jbc.2021.100818

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XBAT31 regulates thermoresponsive hypocotyl growth through mediating degradation of the thermosensor ELF3 in Arabidopsis

Authors: Lin Lin Zhang, Yu Jian Shao, Lan Ding, Mei Jing Wang, Seth Jon Davis, Jian Xiang Liu

Journal: Sci Adv

PubMed ID: 33962946

Doi: 10.1126/sciadv.abf4427

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Open stomata 1 exhibits dual serine/threonine and tyrosine kinase activity in regulating ABA signaling

Authors: Yun Shang, Dami Yang, Yunmi Ha, Ju Yeon Lee, Jin Young Kim, Man-Ho Oh, Kyoung Hee Nam

Journal: J Exp Bot

PubMed ID: 34021330

Doi: 10.1093/jxb/erab225

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Etanercept Protected Against Cigarette Smoke Extract-Induced Inflammation and Apoptosis of Human Pulmonary Artery Endothelial Cells via Regulating TNFR1

Authors: Hong Xue, Baosong Xie, Nengluan Xu, Hongru Li, Qianshun Chen, Weiping Xie, Hong Wang

Journal: Int J Chron Obstruct Pulmon Dis

PubMed ID: 34007171

Doi: 10.2147/COPD.S295580

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