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Antagonistic Ghd7-OsNAC42 Complexes Modulate Carbon and Nitrogen Metabolism to Achieves Superior Quality and High Yield in Rice

Authors: Guangming Lou, Pingli Chen, Pingbo Li, Haozhou Gao, Jiawang Xiong, Shanshan Wan, Yuanyuan Zheng, Yufu Wang, Mufid Alam, Yingnanjun Chen, Lei Wang, Jingjing Bai, Xuan Tan, Wenting Rao, Bian Wu, Hao Zhou, Yanhua Li, Guanjun Gao, Qinglu Zhang, Jinghua Xiao, Xianghua Li, Xuelei Lai, Qifa Zhang, Yuqing He

Journal: Advanced Science

PubMed ID: 40492375

Doi: 10.1002/advs.202504163

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RIG-I-Inducing Small Molecules Potently Inhibit HMA-Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Authors: Xueqin Chen 1, Jiaqi Wu 1, Yuntong Li 1, Jiayu Huang 1, Xiangqin Weng 1, Jiale Wu 1, Shujun Xiao 1 2, Huaxin Song 1, Zhengyuan Wang 1, Ni Yan 1, Fangfang Shi 1, Derun Zheng 1 2, Kai Tan 1 2, Hesong Zhang 1, Jingyi Cui 1 2, Wen Wu 1, Wei Wu 3, Sujiang Zhang 1, Min Lu 1

Journal: Advanced Science

PubMed ID: 40568903

Doi: 10.1002/advs.202414477

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Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R

Authors: Adrian Morales-Pastor, Tamara Miljuš, Miguel Dieguez-Eceolaza, Tomasz Maciej Stępniewski, Vicente Ledesma-Martin, Franziska M Heydenreich, Tilman Flock, Bianca Plouffe, Christian Le Gouill, Jean Duchaine, David A Sykes, Colin Nicholson, Eline J Koers, Wolfgang Guba, Arne C Rufer, Uwe Grether, Michel Bouvier, Dmitry B Veprintsev, Jana Selent

Journal: Nature Communications

PubMed ID: 40500255

Doi: 10.1038/s41467-025-60003-0.

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Functional relocation of the maize chloroplast atpB gene to the nucleus restores photosynthetic competence to a gene-edited non-photosynthetic mutant

Authors: Venkata RamanaRao Mangu, Kelsey Jenkins, Anna Pratt, Kara A Boltz, Leila Pazouki, Alice Y Hui, Muruganantham Mookkan, Jeffrey M Staub

Journal: Plant Biotechnology Journal.

PubMed ID: 40467523

Doi: 10.1111/pbi.70175

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Molecular basis of the hepatobiliary tropism of typhoid toxin promoting Salmonella pathogenicity

Authors: Hwa Young Kim, Gi Young Lee, Andrew J Thompson, Ryan McBride, Dah-Jiun Fu, James C Paulson, Jeongmin Song

Journal: SCIENCE ADVANCES

PubMed ID: 40479051

Doi: 10.1126/sciadv.adt2040

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Chondrocyte fatty acid oxidation drives osteoarthritis via SOX9 degradation and epigenetic regulation

Authors: Zixuan Mei, Kamuran Yilamu, Weiyu Ni, Panyang Shen, Nan Pan, Huasen Chen, Yingfeng Su, Lei Guo, Qunan Sun, Zhaomei Li, Dongdong Huang, Xiangqian Fang, Shunwu Fan, Haitao Zhang, Shuying Shen

Journal: nature COMMUNICATION

PubMed ID: 40425566

Doi: 10.1038/s41467-025-60037-4

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GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization

Authors: Luca Franchini , Joseph J Porter , John D Lueck , Cesare Orlandi

Journal: Nature Communications

PubMed ID: 40374633

Doi: 10.1038/s41467-025-59850-8

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PKMYT1 kinase ameliorates cisplatin sensitivity in osteosarcoma

Authors: Binfeng Liu, Wei Li, Wenchao Zhang, Chengyao Feng, Lu Wan, Shasha He, Ruiling Xu, Zheng Fu, Zhongyue Liu, Haodong Xu, Xin Jin, Chao Tu, Zhihong Li

Journal: Signal Transduct Target Ther

PubMed ID: 40393983

Doi: 10.1038/s41392-025-02250-7

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BARD1-mediated stabilization of METTL14 promotes retinal neovascularization by m6A-modifying MXD1 mRNA on a YTHDF2-dependent manner

Authors: Xianyang Liu, Shuhao Zeng, Jiayu Meng, Qian Zhou, Fan Cao, Baorui Chu, Chao Wu, Yakun Wang, Hui Feng, Xiaorui Bi, Xinyuan Chen, Wenxian Yang, Meng Tian, Hui Yang, Ke Hu, Shengping Hou

Journal: Theranostics

Doi: 10.7150/thno.110122

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Engineered depalmitoylases enable selective manipulation of protein localization and function

Authors: Srinidhi Jayaraman, Audrey Kochiss, Thy-Lan Alcalay, Pedro J. del Rivero Morfin & Manu Ben-Johny

Journal: Nature Communications

PubMed ID: 40223127

Doi: 10.1038/s41467-025-58908-x

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