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All-PEG-Like Block Copolymers Self-Assemble into Stealth Nanocarriers for Drug Delivery

Authors: Parul Sirohi, Brooke E Silverstein, Yulia Shmidov, Sonal Deshpande, Joy Tong, Yvonne Y Ma, Chinmay S Potnis, Soumen Saha, Xinghai Li, Max R Ney, Sarah Y Kim, Joshua J Milligan, Lixin Fan, Matthew L Becker, Daniel Reker, Ashutosh Chilkoti

Journal: Advanced Science

PubMed ID: 41549226

Doi: 10.1002/advs.202517048

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DUSP22 dephosphorylates LGALS1 to enhance T cell-driven antitumor immunity

Authors: Lijian Wang, Yutong Guo, Yujie Dai, Wangsheng Sun, Xiaoying Huang, Haipeng Lei, Aiping Zhang, Shuwen Chen, Yiting Li, Jiani Pan, Yangjian Hong, Lingchuan Ma, Yangyang Feng, Fangyuan Shao, Jianming Zeng, Peng Luo, Junqi Li, Weiting Chen, Na Zhou, Yang Li, Heng Sun, Xiaoling Xu, Chu-Xia Deng, Kai Miao

Journal: Journal for ImmunoTherapy of Cancer

PubMed ID: 41611244

Doi: 10.1136/jitc-2025-013142

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A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

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RING- Type E3 Ligase OsRFPH2- 6 Ubiquitinates Nuclear Factor Y Subunit OsNF- YA1 to Suppress Rice Immunity

Authors: Yan Bi, Leeza Tariq, Hui Wang, Yuqing Yan, Dayong Li, Fengming Song

Journal: Molecular plant pathology

PubMed ID: 41424058

Doi: 10.1111/mpp.70193

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SnRK2.5-mediated phosphorylation of PIN2 links osmotic stress signaling with auxin dependent root adaptive growth in Arabidopsis

Authors: Shujuan Zhang, Zilong Cui, Yu Gao, Qi Liao, Wenyan Li, Siqi Yuan, Zhuomeng Li, Xinwen Zhang, Kai Ding, Wenjing Zhang, Like Shen, Jörg Kudla, Wenhua Zhang, Jing Zhang, Qun Zhang

Journal: Molecular Plant

PubMed ID: 41353562

Doi: 10.1016/j.molp.2025.12.002

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The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue

Authors: Shuai Wang, ShengLan Lin, Fuan Xie, Shuting Liu, Ting He, Kun Chen, Zhengrong Huang, Wenlong Xie, Hongqiu Cheng, Jian Zhang, Weihua Li

Journal: NPJ science of food

PubMed ID: 41390517

Doi: 10.1038/s41538-025-00633-2

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A bispecific antibody targeting PD-L1/TNFR2 increases tumor targeting and enhances antitumor efficacy in colorectal cancer

Authors: Xiaozhen Kang, Peng Qian, Yifeng Han, Mengdi Wu, Yuxin Li, Chun Xu, Jiwu Wei

Journal: Journal for ImmunoTherapy of Cancer

PubMed ID: 41238220

Doi: https://doi.org/10.1136/jitc-2025-013001

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Glutathionylated DNA adducts accumulate in mitochondrial DNA and are regulated by AP endonuclease 1 and tyrosyl-DNA phosphodiesterase 1

Authors: Yu Hsuan Chen, Martin Esparza Sanchez, Ta I Hung, Jin Tang, Wenyan Xu, Jiekai Yin, Yinsheng Wang, Chia-En A Chang, Huimin Zhang, Junjie Chen, Linlin Zhao

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41259143

Doi: doi.org/10.1073/pnas.2509312122

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Intravaginal delivery of mRNA-encoded antibodies with enhanced breadth and potency for SHIV/HIV protection

Authors: Jae Yeon Joo, Peng Xiao, Susan P John, Daryll Vanover, Hannah E Peck, Loren E Sasser, Deepanwita Bose, Younghun Jung, Jaehyeon Hwang, Chiara Zurla, Francois Villinger, Philip J Santangelo

Journal: Nature Communications

PubMed ID: 41290645

Doi: doi.org/10.1038/s41467-025-65456-x

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Structural basis of regulated N-glycosylation at the secretory translocon

Authors: Melvin Yamsek, Mengxiao Ma, Roshan Jha, Yu Wan, Qianru Li, Frank Zhong, Katherine DeLong, Zhe Ji, Rajat Rohatgi, Robert J Keenan

Journal: Nature

PubMed ID: 41261126

Doi: 10.1038/s41586-025-09756-8.

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