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Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers

Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li

Journal: Nature Communications

PubMed ID: 39952937

Doi: 10.1038/s41467-025-56407-7

Products & Services: Recombinant Proteins

Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy

Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song

Journal: Adv Mater

PubMed ID: 39972681

Doi: 10.1002/adma.202411886

Products & Services: Recombinant Proteins

Perturbing Organelle-Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion-Mediated Cancer Immunotherapy

Authors: Jun-Long Liang , Qian-Xiao Huang , Qi-Wen Chen , Xiao-Kang Jin , Zi-Yi Han 1, Ping Ji , Si-Xue Cheng , Wei-Hai Chen , Xian-Zheng Zhang

Journal: Adv Mater

PubMed ID: 39955648

Doi: 10.1002/adma.202416574

Products & Services: Recombinant Proteins

Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice

Authors: Yuxuan Chen , Xiaohong Chen , Yao Zhang , Meng Wang , Minqi Yang , Ruiji Wang , Xiaojie Yan , Shiyi Shao , Huhu Xin , Qida Hu , Wei Wei , Yuan Ping

Journal: Sci Transl Med

PubMed ID: 39813319

Doi: 10.1126/scitranslmed.adl5800

Products & Services: Recombinant Proteins

Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence

Authors: Keyu Kong, Baixing Li, Yongyun Chang, Chen Zhao, Hua Qiao, Minghao Jin, Xinru Wu, Wenxuan Fan, Liao Wang, Yansong Qi, Yongsheng Xu, Zanjing Zhai, Peixiang Ma, Huiwu Li

Journal: Journal of nanobiotechnology

PubMed ID: 39844298

Doi: 10.1186/s12951-025-03103-9

Products & Services: Recombinant Proteins

IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer

Authors: Masataka Amisaki, Abderezak Zebboudj, Hiroshi Yano, Siqi Linsey Zhang, George Payne, Adrienne Kaya Chandra, Rebecca Yu, Pablo Guasp, Zachary M. Sethna, Akihiro Ohmoto, Luis A. Rojas, Charlotte Cheng, Theresa Waters, Alexander Solovyov, Stephen Martis, Ashley S. Doane, Charlotte Reiche, Emmanuel M. Bruno, Martina Milighetti, Kevin Soares, Zagaa Odgerel, John Alec Moral, Julia N. Zhao, Mithat Gönen, …Vinod P. Balachandran

Journal: Nature

PubMed ID: 39814891

Doi: 10.1038/s41586-024-08426-5

Products & Services: Recombinant Proteins

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

Products & Services: Recombinant Proteins

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

Products & Services: Recombinant Proteins

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

Products & Services: Recombinant Proteins

An Oral Nanovaccine Secreted by Genetically Engineered and Ultrasound-Responsive Bacteria for Colon Cancer Immunotherapy

Authors: Jiexin Li, Ruiqi Yang, Yihang Yuan, He Ren, Chao Fang, Jonathan F Lovell, and Yumiao Zhang

Journal: Adv Funct Mater

Doi: 10.1002/adfm.202414994

Products & Services: Peptide Synthesis Recombinant Proteins