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Mesothelin-directed protein-drug conjugates for mesothelin-low solid tumor therapy

Authors: Ying Wang, Jiayao Yan, Lin Li, Tianran Chen, Jingyi Guo, Lei Lei, Siwen Wu, Lijing Zhu, Xiaotong Chen, Baorui Liu

Journal: Nature Communications

PubMed ID: 40849430

Doi: 10.1038/s41467-025-63269-6.

Products & Services: Recombinant Proteins

Optimised modular anti‐FLAG CAR T cells for solid tumor therapy

Authors: Xiaomeng Zhang, Rachel Xu, Dmitry Zorin, Evan G Pappas, Jiawei Tang, Yuchen Bai, Vicky M Qin, Bianca von Scheidt, Ruihong Huang, Weronika Kulakowska, Charbel Darido, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney

Journal: Clinical & Translational Immunology

PubMed ID: 40851786

Doi: 10.1002/cti2.70046

Products & Services: Recombinant Proteins Gene Synthesis

A Covalent Self-Reporting Peptide Degrader Enables Real-Time Monitoring of Targeted Protein Degradation In Vivo

Authors: Wei Zhang, Lizhen Yuan, Rui Liu, Yanbo Jing, Shijun Lin, Hao Fang, Yuxuan Li, Xiaohui Zhang, Jun Dai, Tao Liu, Fan Xia, Xiaoding Lou

Journal: J Am Chem Soc

PubMed ID: 40717291

Doi: 10.1021/jacs.5c07041

Products & Services: Recombinant Proteins

β-catenin functions as a molecular adapter for disordered cBAF interactions

Authors: Yuen San Chan, Qinyu Gao, Sarah A Robinson, Wenzhi Wang, Ruzena Filandrova, Lisa-Maria Weinhold, Mario Loeza Cabrera, Miao Zhang, Chandra Shekar R Ambati, Antonio M Lerario, Nagireddy Putluri, Katja Kiseljak-Vassiliades, Margaret E Wierman, Mouhammed Amir Habra, Gary D Hammer, Vaclav Veverka, Katerina Cermakova, H Courtney Hodges

Journal: Molecular Cell

PubMed ID: 40695292

Products & Services: Recombinant Proteins

An all-silk-based functional system promotes tendon regeneration by regulating the cell fate of TSPCs in an inflammatory microenvironment

Authors: Qingyun Mo, Haotian Zheng, Chuanquan Liu, Yuzhi Sun, Zhicheng Cao, Renwang Sheng, Yanan Zhang, Mingyue Wang, Baian Kuang, Ludvig J Backman, Jiaxiang Li, Wei Zhang, Jialin Chen

Journal: Acta Biomaterialia

PubMed ID: 40409996

Doi: 10.1016/j.actbio.2025.05.040

Products & Services: Recombinant Proteins

AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition

Authors: Keyu Kong, Li Liu, Renfang Zhang, Yongyun Chang, Yueming Shao, Chen Zhao, Hua Qiao, Minghao Jin, Xuzhuo Chen, Wentao Shi, Xinru Wu, Wenxuan Fan, Yuehao Hu, Kewei Rong, Pu Zhang, Baixing Li, Jingwei Zhang, Peixiang Ma, Xiaoling Zhang, Huiwu Li, Zanjing Zhai

Journal: Bone Research

PubMed ID: 40461512

Doi: 10.1038/s41413-025-00431-2

Products & Services: Recombinant Proteins

Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response

Authors: Kenta Matsuda, Mitra Harrison, Eleanor Wettstein, Jessica Pederson, Alyssa A Pullano, Lyuba Bolkhovitinov, Breanna Kim, Isabel Steinberg, Trevor Griesman, Sarah Stuccio, Daniel Rogan, Andy Patamawenu, Tulley Shofner, Nathaniel E Wright, Jonathan D Webber, Freya Van't Veer, Rachel Roenicke, Emma Koory, Peyton M Roeder, Ellison Ober, Benjamin Leach, Yaroslav Tsybovsky, Tyler Stephens, Ivan Del Moral-Sanchez, Ilja Bontjer, Lori W McGinnes-Cullen, Eric Chu, Jason Liang, Jonathan L Torres, Ryan N Lin, Andy S Tran, Gabrielle Dziubla, Leonid Serebryannyy, Sandeep Narpala, Bob Lin, Mike Castro, Gabriel Ozorowski, Andrew B Ward, Rogier W Sanders, Peter D Kwong, Javier Guenaga, Richard Wyatt, Trudy Morrison, Mark Connors

Journal: Nature Communications

PubMed ID: 40461490

Doi: 10.1038/s41467-025-60481-2

Products & Services: Recombinant Proteins

Stomata-targeted nanocarriers enhance plant defense against pathogen colonization

Authors: Suppanat Puangpathumanond, Heng Li Chee, Cansu Sevencan, Xin Yang, On Sun Lau, Tedrick Thomas Salim Lew

Journal: Nature Communications

PubMed ID: 40410152

Doi: 10.1038/s41467-025-60112-w

Products & Services: Recombinant Proteins

Developmentally endothelial locus-1 facilitates intestinal inflammation resolution by suppressing the Cmpk2-cGAS-STING pathway and promoting reparatory macrophage transition

Authors: Meihui Tao, Li Wang, Chaoyue Chen, Mengfan Tang, Yanping Wang, Jingyue Zhang, Xi Zhao, Qinyu Feng, Junfa Chen, Wei Yan, Rong Lin, Yu Fu

Journal: Journal of Advanced Research

PubMed ID: 40288675

Doi: 10.1016/j.jare.2025.04.030

Products & Services: Mammalian Expression Recombinant Proteins

Fullerol Initiates Stem Cell–Nanomaterials Interactions for Enhanced Tissue Regeneration via Clathrin-Mediated Endocytosis and Nuclear Factor Erythroid 2-Related Factor 2 Signaling

Authors: Haoyang Liu, Yue Zhu, Weixu Chen, Renwang Sheng, Chuanquan Liu, Yuzhi Sun, Jia Liu, Mingyue Wang, Jun Lu, Jialin Chen, Wei Zhang

Journal: ACS Applied Materials & Interfaces

Doi: 10.1021/acsami.5c01731

Products & Services: Recombinant Proteins