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BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

Authors: Ugur Sahin, Alexander Muik, Isabel Vogler, Evelyna Derhovanessian, Lena M Kranz, Mathias Vormehr, Jasmin Quandt, Nicole Bidmon, Alexander Ulges, Alina Baum, Kristen E Pascal, Daniel Maurus, Sebastian Brachtendorf, Verena Lörks, Julian Sikorski, Peter Koch, Rolf Hilker, Dirk Becker, Ann-Kathrin Eller, Jan Grützner, Manuel Tonigold, Carsten Boesler, Corinna Rosenbaum, Ludwig Heesen, Marie-Cristine Kühnle, Asaf Poran, Jesse Z Dong, Ulrich Luxemburger, Alexandra Kemmer-Brück, David Langer, Martin Bexon, Stefanie Bolte, Tania Palanche, Armin Schultz, Sybille Baumann, Azita J Mahiny, Gábor Boros, Jonas Reinholz, Gábor T Szabó, Katalin Karikó, Pei-Yong Shi, Camila Fontes-Garfias, John L Perez, Mark Cutler, David Cooper, Christos A Kyratsous, Philip R Dormitzer, Kathrin U Jansen, Özlem Türeci

Journal: Nature

PubMed ID: 34044428

Doi: 10.1038/s41586-021-03653-6

Products & Services: Mammalian Expression

Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms

Authors: Xiaojie Shi, Yue Wan, Nan Wang, Jiangchao Xiang, Tao Wang, Xiaofeng Yang, Ju Wang, Xuxue Dong, Liang Dong, Lei Yan, Yu Li, Lili Liu, Shinchen Hou, Zhenwei Zhong, Ian A Wilson, Bei Yang, Guang Yang, Richard A Lerner

Journal: Nat Commun

PubMed ID: 33953162

Doi: 10.1038/s41467-021-22810-z

Products & Services: Mammalian Expression

NFAT5 Is Involved in GRP-Enhanced Secretion of GLP-1 by Sodium

Authors: Caini Fan, Laureano D Asico, Van Anthony M Villar, Jessica Hunt, Santiago Cuevas, Ines Armando, Pedro A Jose, Prasad R Konkalmatt

Journal: Int J Mol Sci

PubMed ID: 33921209

Doi: 10.3390/ijms22083951

Products & Services: Mammalian Expression

Transgene codon usage drives viral fitness and therapeutic efficacy in oncolytic adenoviruses

Authors: Estela Núñez-Manchón, Martí Farrera-Sal, Marc Otero-Mateo, Giancarlo Castellano, Rafael Moreno, David Medel, Ramon Alemany, Eneko Villanueva, Cristina Fillat

Journal: NAR Cancer

PubMed ID: 34316705

Doi: 10.1093/narcan/zcab015

Products & Services: Mammalian Expression

Plasmin-resistant PSD-95 inhibitors resolve effect-modifying drug-drug interactions between alteplase and nerinetide in acute stroke

Authors: Diana Mayor-Nunez, Zhanxin Ji, Xiujun Sun, Lucy Teves, J David Garman, Michael Tymianski

Journal: Sci Transl Med

PubMed ID: 33827973

Doi: 10.1126/scitranslmed.abb1498

Products & Services: Mammalian Expression

FGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling

Authors: Huang-Ming Chang, Kang-Yung Peng, Chieh-Kai Chan, Chiao-Yin Sun, Ying-Ying Chen, Han-Mei Chang, Chun-Lin Huang, Pei-Chun Liu, Peng-Ying Chen, Kuo-Chuan Wang, Wei-Jie Wang, Chen-Chi Wu, Yu-Feng Lin, Tai-Shuan Lai, Tao-Min Huang, Guang-Huar Young, Shuei-Liong Lin, Marlies Ostermann, Tzong-Shinn Chu, Jeff S Chueh, Vin-Cent Wu

Journal: Cell Death Dis

PubMed ID: 33866326

Doi: 10.1038/s41419-021-03693-w

Products & Services: Mammalian Expression

Molecular Interactions between Two LMP2A PY Motifs of EBV and WW Domains of E3 Ubiquitin Ligase AIP4

Authors: Min-Duk Seo, Seung-Hyeon Seok, Ji-Hun Kim, Ji Woong Choi, Sung Jean Park, Bong-Jin Lee

Journal: Life (Basel)

PubMed ID: 33922228

Doi: 10.3390/life11050379

Products & Services: Mammalian Expression

Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses

Authors: Gabriela Alvarado; Wilhelm Salmen; Khalil Ettayebi; Liya Hu; Banumathi Sankaran; Mary K. Estes; B. V. Venkataram Prasad; James E. Crowe

Journal: Nature Communications

PubMed ID: 34262046

Doi: 10.1038/s41467-021-24649-w

Products & Services: Mammalian Expression

Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses

Authors: Gabriela Alvarado; Wilhelm Salmen; Khalil Ettayebi; Liya Hu; Banumathi Sankaran; Mary K. Estes; B. V. Venkataram Prasad; James E. Crowe

Journal: Nature Communications

PubMed ID: 34262046

Doi: 10.1038/s41467-021-24649-w

Products & Services: Mammalian Expression

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

Authors: Alessia Balestrini, Victory Joseph, Michelle Dourado, Rebecca M Reese, Shannon D Shields, Lionel Rougé, Daniel D Bravo, Tania Chernov-Rogan, Cary D Austin, Huifen Chen, Lan Wang, Elisia Villemure, Daniel G M Shore, Vishal A Verma, Baihua Hu, Yong Chen, Laurie Leong, Chris Bjornson, Kathy Hötzel, Alvin Gogineni, Wyne P Lee, Eric Suto, Xiumin Wu, John Liu, Juan Zhang, Vineela Gandham, Jianyong Wang, Jian Payandeh, Claudio Ciferri, Alberto Estevez, Christopher P Arthur, Jens Kortmann, Ryan L Wong, Jose E Heredia, Jonas Doerr, Min Jung, Jason A Vander Heiden, Merone Roose-Girma, Lucinda Tam, Kai H Barck, Richard A D Carano, Han Ting Ding, Bobby Brillantes, Christine Tam, Xiaoying Yang, Simon S Gao, Justin Q Ly, Liling Liu, Liuxi Chen, Bianca M Liederer, Joseph H Lin, Steven Magnuson, Jun Chen, David H Hackos, Justin Elstrott, Alexis Rohou, Brian S Safina, Matthew Volgraf, Rebecca N Bauer, Lorena Riol-Blanco

Journal: J Exp Med

PubMed ID: 33620419

Doi: 10.1084/jem.20201637

Products & Services: Mammalian Expression