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Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes

Authors: Taniya Bhardwaj, Kundlik Gadhave, Shivani K Kapuganti, ProfilePrateek Kumar, ProfileZacharias Faidon Brotzakis, Kumar Udit Saumya, Namyashree Nayak, Ankur Kumar, Neha Garg, Michele Vendruscolo, ProfileRajanish Giri

Journal: biorxiv

Doi: doi.org/10.1101/2021.05.29.446267

Products & Services: Peptide Synthesis

A novel cell-penetrating peptide targeting calpain-cleavage of PSD-95 induced by excitotoxicity improves neurological outcome after stroke

Authors: Sara Ayuso-Dolado, Gema M Esteban-Ortega, Óscar G Vidaurre, Margarita Díaz-Guerra

Journal: Theranostics.

PubMed ID: 34093851

Doi: 10.7150/thno.60701

Products & Services: Peptide Synthesis

A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation

Authors: Yong Han, Guobin Xia, Yanlin He, Yang He, Monica Farias, Yong Xu, Qi Wu

Journal: Sci Adv

PubMed ID: 34039606

Doi: 10.1126/sciadv.abf8719

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Yeast Bromodomain Factor 1 and Its Human Homolog TAF1 Play Conserved Roles in Promoting Homologous Recombination

Authors: Haoyang Peng, Simin Zhang, Yihan Peng, Shuangyi Zhu, Xin Zhao, Xiaocong Zhao, Shuangshuang Yang, Guangxue Liu, Yang Dong, Xiaoli Gan, Qing Li, Xinghua Zhang, Huadong Pei, Xuefeng Chen

Journal: Adv Sci (Weinh)

PubMed ID: 34056863

Doi: 10.1002/advs.202100753

Products & Services: Peptide Synthesis

Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET

Authors: Charles S Lay, Angela Bridges, Joelle Goulding, Stephen J Briddon, Zoja Soloviev, Peter D Craggs, Stephen J Hill

Journal: Cell Chem Biol

PubMed ID: 34038748

Doi: 10.1016/j.chembiol.2021.05.002

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Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy

Authors: Ethan W Hass, Zachary A Sorrentino, Grace M Lloyd, Nikolaus R McFarland, Stefan Prokop, Benoit I Giasson

Journal: Acta Neuropathol Commun

PubMed ID: 33941284

Doi: 10.1186/s40478-021-01173-y

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Genes associated with amyloid-beta-induced inflammasome-mediated neuronal death identified using functional gene trap mutagenesis approach

Authors: Jeremy Kean Yi Yap, Benjamin Simon Pickard, Sook Yee Gan, Elaine Wan Ling Chan

Journal: Int J Biochem Cell Biol

PubMed ID: 34022435

Doi: 10.1016/j.biocel.2021.106014

Products & Services: Peptide Synthesis

Development of a simplified, sensitive, and accurate LC-MS/MS method for peanut quantification in wheat flour-based dry matrices

Authors: Yuwei Chang, Hong Peng, Guangtao Zhang

Journal: Food Addit Contam Part A Chem Anal Control Expo Risk Assess

PubMed ID: 34047678

Doi: 10.1080/19440049.2021.1923822

Products & Services: Peptide Synthesis

The human anti-CD40 agonist antibody mitazalimab (ADC-1013; JNJ-64457107) activates antigen-presenting cells, improves expansion of antigen-specific T cells, and enhances anti-tumor efficacy of a model cancer vaccine in vivo

Authors: Adnan Deronic, Anneli Nilsson, Mia Thagesson, Doreen Werchau, Karin Enell Smith, Peter Ellmark

Journal: Cancer Immunol Immunother

PubMed ID: 33948686

Doi: 10.1007/s00262-021-02932-5

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Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide

Authors: Timothy A Wiles, Anita Hohenstein, Laurie G Landry, Mylinh Dang, Roger Powell, Perrin Guyer, Eddie A James, Maki Nakayama, Kathryn Haskins, Thomas Delong, Rocky L Baker

Journal: Front Immunol

PubMed ID: 34113344

Doi: 10.3389/fimmu.2021.668680

Products & Services: Peptide Synthesis