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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
Authors: Alexander J Garvin, Alexander J Lanz, George E Ronson, Matthew J W Mackintosh, Katarzyna Starowicz, Alexandra K Walker, Yara Aghabi, Hannah MacKay, Ruth M Densham, Jai S Bhachoo, Aneika C Leney, Joanna R Morris
Journal: Mol Cell
PubMed ID: 40054443
Doi: 10.1016/j.molcel.2025.02.004
Active- and Allosteric-Site Cyclic Peptide Inhibitors of Secreted M. tuberculosis Chorismate Mutase
Authors: Renier H P van Neer, Patricia K Dranchak, Mahesh Aitha, Lijun Liu, Emma K Carlson, Isabella E Jacobsen, Kevin Battaile, Yuhong Fang, Dingyin Tao, Ganesha Rai, Janak Padia, Scott Lovell, Hiroaki Suga, James Inglese
Journal: ACS Infectious Diseases
PubMed ID: 39903128
Doi: 10.1021/acsinfecdis.4c00798
Products & Services: Peptide Synthesis   Plasmid DNA Preparation   
Structures of complete HIV-1 TAR RNA portray a dynamic platform poised for protein binding and structural remodeling
Authors: Charles Bou-Nader, Katie A Link, Krishna C Suddala, Jay R Knutson, Jinwei Zhang
Journal: Nature Communications
PubMed ID: 40050622
Doi: 10.1038/s41467-025-57519-w
Products & Services: Peptide Synthesis   
Overlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis
Authors: Jitka Blazickova, Shalini Trivedi, Richard Bowman, Sowmya Sivakumar Geetha, Silma Subah, Michelle Scuzzarella, Alexander Chang, Uma R Chandran, Judith L Yanowitz, Sarit Smolikove, Verena Jantsch, Monique Zetka, Nicola Silva
Journal: Nature Communications
PubMed ID: 40082424
Doi: 10.1038/s41467-025-57862-y
Products & Services: Peptide Synthesis   
Epstein-Barr virus infection promotes T cell dysregulation in a humanized mouse model of multiple sclerosis
Authors: Jessica R Allanach, Naomi M Fettig, Blair K Hardman, Ariel R Rosen, Vina Fan, Cynthia Chung, Erin J Goldberg, Zachary J Morse, Iryna Shanina, Galina Vorobeychik, Lisa C Osborne, Marc S Horwitz
Journal: SCIENCE ADVANCES
PubMed ID: 40043135
Doi: 10.1126/sciadv.adu5110
Products & Services: Peptide Synthesis   
Self-assembly GSH response based Buforin IIb-Olaparib nanocombination synergistically promotes DNA damage for prostate cancer immunotherapy
Authors: Maosong Hu , Yuyu Zhu , Xinyi Tang , Jing Xu , Hanbin Ma , Zhihan Chen , Duo Chen , Wenyuan Wu , Xialin Chen , Rongrong He , Jing Zhou , Jinao Duan , Weiguo Chen , Hongyue Ma
Journal: Chemical Engineering Journal
Doi: 10.1016/j.cej.2025.160862
Products & Services: Peptide Synthesis   
Deciphering molecular specificity in MCL-1/BAK interaction and its implications for designing potent MCL-1 inhibitors
Authors: Hudie Wei, Haolan Wang, Shuang Xiang, Jiaqi Wang, Lingzhi Qu, Xiaojuan Chen, Ming Guo, Xiaoyun Lu, Yongheng Chen
Journal: Cell Death Differ
PubMed ID: 39901037
Doi: 10.1038/s41418-025-01454-2
Products & Services: Peptide Synthesis   
Structures of HCoV-OC43 HR1 Domain in Complex with Cognate HR2 or Analogue EK1 Peptide
Authors: Xiuxiu He, Huanzhen Liu, Guang Yang, Lei Yan
Journal: Viruses-Basel
PubMed ID: 40143271
Doi: 10.3390/v17030343
Products & Services: Peptide Synthesis   
The TaCLE24b peptide signaling cascade modulates lateral root development and drought tolerance in wheat
Authors: Wen Yang, Man Feng, Kuohai Yu, Jie Cao, Guangxian Cui, Yumei Zhang, Huiru Peng, Yingyin Yao, Zhaorong Hu, Zhongfu Ni, Feng Qin, Fuminori Takahashi, Qixin Sun, Mingming Xin
Journal: Nature Communications
PubMed ID: 40000659
Doi: 10.1038/s41467-025-57291-x
Products & Services: Peptide Synthesis   
CK2B Induces CD8+ T-Cell Exhaustion through HDAC8-Mediated Epigenetic Reprogramming to Limit the Efficacy of Anti-PD-1 Therapy in Non-Small-Cell Lung Cancer
Authors: Shaochuan Liu, Shiya Ma, Gen Liu, Lingjie Hou, Yong Guan, Liang Liu, Yuan Meng, Wenwen Yu, Ting Liu, Li Zhou, Zhiyong Yuan, Shuju Pang, Siyuan Zhang, Junyi Li, Xiubao Ren, Qian Sun
Journal: Advanced Science
PubMed ID: 40013761
Doi: 10.1002/advs.202411053
Products & Services: Peptide Synthesis   
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