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Thrombus-targeted nanoparticles for thrombin-triggered thrombolysis and local inflammatory microenvironment regulation

Authors: Huijuan Zhang, Hongyan Qu, Qingqing He, Linyu Gao, Hongling Zhang, Yongfu Wang, Zhenzhong Zhang, Lin Hou

Journal: J Control Release

PubMed ID: 34214595

Doi: 10.1016/j.jconrel.2021.06.043

Products & Services: Peptide Synthesis

The interplay of self-assembly and target binding in centrin 1 from Toxoplasma gondii

Authors: Carolina Conter, Luca Bombardi, Marco Pedretti, Filippo Favretto, Adele Di Matteo, Paola Dominici, Alessandra Astegno

Journal: Biochem J

PubMed ID: 34114596

Doi: 10.1042/BCJ20210295

Products & Services: Peptide Synthesis

Identification of a Glypican-3 binding peptide from a phage-displayed peptide library for PET imaging of hepatocellular carcinoma

Authors: Jiayao Yan, Xiaoxiao Yu, Xiaotong Chen, Fangcen Liu, Fangjun Chen, Naiqing Ding, Lixia Yu, Fanyan Meng, Jie Shen, Jia Wei and Baorui Liu

Journal: Frontiers in Oncology

PubMed ID: 34150644

Products & Services: Peptide Synthesis

Rapid single-molecule detection of COVID-19 and MERS antigens via nanobody-functionalized organic electrochemical transistors

Authors: Keying Guo, Shofarul Wustoni, Anil Koklu, Escarlet Díaz-Galicia, Maximilian Moser, Adel Hama, Ahmed A Alqahtani, Adeel Nazir Ahmad, Fatimah Saeed Alhamlan, Muhammad Shuaib, Arnab Pain, Iain McCulloch, Stefan T Arold, Raik Grünberg, Sahika Inal

Journal: Nat Biomed Eng

PubMed ID: 34031558

Doi: 10.1038/s41551-021-00734-9

Products & Services: Peptide Synthesis

A nematode-derived, mitochondrial stress signaling-regulated peptide exhibits broad antibacterial activity

Authors: Madhab Sapkota, Mohammed Adnan Qureshi, Siraje Arif Mahmud, Yves Balikosa, Charlton Nguyen, Joseph M Boll, Mark W Pellegrino

Journal: Biol Open

PubMed ID: 34184732

Doi: 10.1242/bio.058613

Products & Services: Peptide Synthesis

Protein Sumoylation Is Crucial for Phagocytosis in Trophozoites

Authors: Mitzi Díaz-Hernández, Rosario Javier-Reyna, Izaid Sotto-Ortega, Guillermina García-Rivera, Sarita Montaño, Abigail Betanzos, Dxinegueela Zanatta, Esther Orozco

Journal: Int J Mol Sci

PubMed ID: 34071922

Doi: 10.3390/ijms22115709

Products & Services: Peptide Synthesis

A novel cell-penetrating peptide targeting calpain-cleavage of PSD-95 induced by excitotoxicity improves neurological outcome after stroke

Authors: Sara Ayuso-Dolado, Gema M Esteban-Ortega, Óscar G Vidaurre, Margarita Díaz-Guerra

Journal: Theranostics.

PubMed ID: 34093851

Doi: 10.7150/thno.60701

Products & Services: Peptide Synthesis

Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes

Authors: Taniya Bhardwaj, Kundlik Gadhave, Shivani K Kapuganti, ProfilePrateek Kumar, ProfileZacharias Faidon Brotzakis, Kumar Udit Saumya, Namyashree Nayak, Ankur Kumar, Neha Garg, Michele Vendruscolo, ProfileRajanish Giri

Journal: biorxiv

Doi: doi.org/10.1101/2021.05.29.446267

Products & Services: Peptide Synthesis

Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET

Authors: Charles S Lay, Angela Bridges, Joelle Goulding, Stephen J Briddon, Zoja Soloviev, Peter D Craggs, Stephen J Hill

Journal: Cell Chem Biol

PubMed ID: 34038748

Doi: 10.1016/j.chembiol.2021.05.002

Products & Services: Peptide Synthesis

Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy

Authors: Ethan W Hass, Zachary A Sorrentino, Grace M Lloyd, Nikolaus R McFarland, Stefan Prokop, Benoit I Giasson

Journal: Acta Neuropathol Commun

PubMed ID: 33941284

Doi: 10.1186/s40478-021-01173-y

Products & Services: Peptide Synthesis