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OsPRMT6b balances plant growth and high temperature stress by feedback inhibition of abscisic acid signaling

Authors: Xin Jin, Qibing Lin, Xinyue Zhang, Shuang Zhang, Weiwei Ma, Peike Sheng, Limin Zhang, Minxi Wu, Xudong Zhu, Zhiwei Li, Bojuan Liu, Jiachang Wang, Yupeng Wang, Kun Dong, Ming Yu, Yulong Ren, Zhijun Cheng, Cailin Lei, Xiuping Guo, Xin Wang, Haiyang Wang, Fu-Qing Wu, Shanshan Zhu, Jianmin Wan

Journal: Nature Communications

PubMed ID: 40467572

Doi: 10.1038/s41467-025-60350-y

Products & Services: Peptide Synthesis

Host protein ARF1 is a proviral factor for SARS-CoV-2 and a candidate broad-spectrum therapeutic target

Authors: Cunhuan Zhang, Yuan-Qin Min, Heng Xue, Haiyan Zhang, Kunpeng Liu, Yichao Tian, Ziying Yang, Zihan Zhao, Hang Yang, Chao Shan, Xiulian Sun & Yun-Jia Ning

Journal: nature COMMUNICATION

Doi: 10.1038/s41467-025-61431-8

Products & Services: Peptide Synthesis

An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP

Authors: Liangxuan Qi, Jing Li, Shuai Li, Jing Li, Han Wang, Lei Yang, Xinyang Tan, Zhichang Zhao, Guanghua Luo, Maofeng Jing, Ary A Hoffmann, Jichao Fang, Rui Ji

Journal: Advanced Science

PubMed ID: 40167256

Doi: 10.1002/advs.202415474

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Cathepsin L-dependent positive selection shapes clonal composition and functional fitness of CD4+ T cells

Authors: Elisabetta Petrozziello, Amina Sayed, João A Freitas, Christine Federle, Jelena Nedjic, Sarina Ravens, Batuhan Akçabozan, Anna M Schulz, Dietmar Zehn, Marc Schmidt-Supprian, Reinhard Obst, Immo Prinz, Martijn Verdoes, Jan Kisielow, Thomas Reinheckel, Tobias Straub, Stephen R Daley, Ludger Klein

Journal: nature immunology

PubMed ID: 40514418

Doi: 10.1038/s41590-025-02182-y

Products & Services: Peptide Synthesis

LPS-enriched interaction drives spectrum conversion in antimicrobial peptides: Design and optimization of AA16 derivatives for targeting gram-negative bacteria

Authors: Wanyang Xiao, Ruize Sun, Jietao Lou, Yanyan Xu, Xiaokun Li, Kaiyun Xin, Weijie Lu, Chenhui Sun, Tianbao Chen, Yitian Gao, Di Wu

Journal: Eur J Med Chem

PubMed ID: 40048797

Doi: 10.1016/j.ejmech.2025.117462

Products & Services: Peptide Synthesis

Structural basis for hepatitis E virus neutralization by potent human antibodies

Authors: Luis M Molinos-Albert, Eduard Baquero, Cyril Planchais, Virginie Doceul, Hicham El Costa, Estelle Mottez, Vincent Mallet, Stanislas Pol, Matthew L Albert, Nicole Pavio, Cécile Alanio, Jordan D Dimitrov, Hugo Mouquet

Journal: SCIENCE ADVANCES

PubMed ID: 40333967

Doi: 10.1126/sciadv.adu8811

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A rationally designed injury kidney targeting peptide library and its application in rescuing acute kidney injury

Authors: Yushuo Xiao, Zhijian Tong, Huidie Xu, Zhouyan Jia, Chen Wang, Yang Cao, Liangliang Song, Siyu Hao, Jing Yang, Yihao Zhou, Yunhao Xie, Peng Wu, Tong He, Yancai Wu, Robert B Petersen, Anlin Peng, Chun Zhang, Hong Chen, Ling Zheng, Kun Huang

Journal: SCIENCE ADVANCES

PubMed ID: 40315322

Doi: 10.1126/sciadv.adt3943

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Import mechanism of peroxisomal proteins with an N-terminal signal sequence

Authors: Michael L Skowyra , Tom A Rapoport

Journal: Nature Cell Biology

PubMed ID: 40346349

Doi: 10.1038/s41556-025-01662-5

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A novel, covalent broad-spectrum inhibitor targeting human coronavirus Mpro

Authors: Jing Sun, Deheng Sun, Qi Yang, Dong Wang, Jingjing Peng, Hu Guo, Xiaoyu Ding, Zhao Chen, Bin Yuan, Yan A Ivanenkov, Jinwei Yuan, Bogdan A Zagribelnyy, Yiyun He, Jingyi Su, Ling Wang, Jielin Tang, Zhun Li, Rong Li, Taotao Li, Xiaoyu Hu, Xing Liang, Airu Zhu, Peilan Wei, Yaya Fan, Sang Liu, Jie Zheng, Xin Guan, Alex Aliper, Minglei Yang, Dmitry S Bezrukov, Zhanhong Xie, Victor A Terentiev, Guilin Peng, Daniil A Polykovskiy, Alexander S Malyshev, Maxim N Malkov, Qingsong Zhu, Alán Aspuru-Guzik, Xiao Ding, Xin Cai, Man Zhang, Jingxian Zhao, Nanshan Zhong, Feng Ren, Xinwen Chen, Alex Zhavoronkov, Jincun Zhao

Journal: Nature Communications

PubMed ID: 40374668

Doi: 10.1038/s41467-025-59870-4

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Mechanism of D-type cyclin recognition by the AMBRA1 E3 ligase receptor

Authors: Yang Wang, Ming Liu, Shan Wang, Xinyi Mai, Xi Wang, Fei Teng, Tianrui Lyu, Ming-Yuan Su, Goran Stjepanovic

Journal: SCIENCE ADVANCES

PubMed ID: 40408472

Doi: 10.1126/sciadv.adu8708

Products & Services: Peptide Synthesis