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Mapping the Pareto optimal design space for a functionally deimmunized biotherapeutic candidate.

Authors: SalvatRegina S，ParkerAndrew S，ChoiYoonjoo，Bailey-KelloggChris，GriswoldKa

Journal: PLoS Comput. Biol.

PubMed ID: 25568954

Doi: 10.1371/journal.pcbi.1003988

Products & Services: Peptide Synthesis

Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts.

Authors: PerezC，JukicaA，ListopadJ J，AndersK，KühlA A，LoddenkemperC，BlankensteinT，Ch

Journal: Int. J. Cancer

PubMed ID: 25530110

Doi: 10.1002/ijc.29401

Products & Services: Peptide Synthesis

Prime-boost vaccination with Bacillus Calmette Guerin and a recombinant adenovirus co-expressing CFP10， ESAT6， Ag85A and Ag85B of Mycobacterium tuberculosis induces robust antigen-specific immune responses in mice.

Authors: LiWu，LiMin，DengGuangcun，ZhaoLiping，LiuXiaoming，WangYuj

Journal: Mol Med Rep

PubMed ID: 25962477

Doi: 10.3892/mmr.2015.3770

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The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization.

Authors: RohrbachTimothy D，ShahNishi，JacksonWilliam P，FeeneyErin V，ScanlonSamantha，GishRobert，KhodadadiRyan，HydeStephen O，HicksPatricia H，AndersonJoshua C，JarboeJohn S，WilleyChristoph

Journal: PLoS ONE

PubMed ID: 26470026

Doi: 10.1371/journal.pone.0140870

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Immunization with Recombinant Adenoviral Vectors Expressing HCV Core or F Proteins Leads to T Cells with Reduced Effector Molecules Granzyme B and IFN-γ: A Potential New Strategy for Immune Evasion in HCV Infection.

Authors: SamratSubodh Kumar，VediSatish，SinghShakti，LiWen，KumarRakesh，AgrawalBa

Journal: Viral Immunol.

PubMed ID: 26133045

Doi: 10.1089/vim.2015.0009

Products & Services: Peptide Synthesis

Phosphorylation of Glutathione S-Transferase P1 (GSTP1) by Epidermal Growth Factor Receptor (EGFR) Promotes Formation of the GSTP1-c-Jun N-terminal kinase (JNK) Complex and Suppresses JNK Downstream Signaling and Apoptosis in Brain Tumor Cells.

Authors: OkamuraTatsunori，AntounGamil，KeirStephen T，FriedmanHenry，BignerDarell D，Ali-OsmanFra

Journal: J. Biol. Chem.

PubMed ID: 26429914

Doi: 10.1074/jbc.M115.656140

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Immunomodulator-based enhancement of anti smallpox immune responses.

Authors: MartínezOsmarie，MirandaEric，RamírezMaite，SantosSaritza，RiveraCarlos，VázquezLuis，SánchezTomás，TremblayRaymond L，Ríos-OlivaresEddy，OteroMi

Journal: PLoS ONE

PubMed ID: 25875833

Doi: 10.1371/journal.pone.0123113

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Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.

Authors: Reddy VB, Sun S, Azimi E, Elmariah SB, Dong X, Lerner EA.

Journal: Nat Commun

PubMed ID: 26216096

Doi: 10.1038/ncomms8864

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Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice.

Authors: Obenaus M, Leitão C, Leisegang M, Chen X, Gavvovidis I, van der Bruggen P, Uckert W, Schendel DJ, Blankenstein T.

Journal: Nat Biotechnol

PubMed ID: 25774714

Doi: 10.1038/nbt.3147

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A SNARE-Like Protein and Biotin Are Implicated in Soybean Cyst Nematode Virulence.

Authors: Bekal S, Domier LL, Gonfa B, Lakhssassi N, Meksem K, Lambert KN.

Journal: PLoS ONE

PubMed ID: 26714307

Doi: 10.1371/journal.pone.0145601

Products & Services: Peptide Synthesis