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A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces.

Authors: RileyTimothy P，AyresCory M，HellmanLance M，SinghNishant K，CosianoMichael，CimonsJennifer M，AndersonMichael J，PiepenbrinkKurt H，PierceBrian G，WengZhiping，BakerBri

Journal: Protein Eng. Des. Sel.

PubMed ID: 27624308

Doi: 10.1093/protein/gzw050

Products & Services: Peptide Synthesis

Structure of an α-Helical Peptide and Lipopeptide Bound to the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule CD1d.

Authors: GirardiEnrico，WangJing，ZajoncDi

Journal: J. Biol. Chem.

PubMed ID: 27006394

Doi: 10.1074/jbc.M115.702118

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Functional characterization of hepatitis B virus core promoter mutants revealed transcriptional interference among co-terminal viral mRNAs.

Authors: ChenChaoyang，JiaHaodi，ZhangFei，QinYanli，ZongLi，YuanQuan，WangYongxiang，XiaNingshao，LiJisu，WenYumei，TongShu

Journal: J. Gen. Virol.

PubMed ID: 27558941

Doi: 10.1099/jgv.0.000590

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Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.

Authors: Clement M, Marsden M, Stacey MA, Abdul-Karim J, Gimeno Brias S, Costa Bento D, Scurr MJ, Ghazal P, Weaver CT, Carlesso G, Clare S, Jones SA, Godkin A, Jones GW, Humphreys IR,.

Journal: PLoS Pathog

PubMed ID: 27926930

Doi: 10.1371/journal.ppat.1006050

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Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities.

Authors: Chang AN, Mahajan P, Knapp S, Barton H, Sweeney HL, Kamm KE, Stull JT.

Journal: Proc Natl Acad Sci U S A

PubMed ID: 27325775

Doi: 10.1073/pnas.1600633113

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Protein unfolding as a switch from self-recognition to high-affinity client binding.

Authors: Groitl B, Horowitz S,, Makepeace KAT, Petrotchenko EV, Borchers CH, Reichmann D, Bardwell JCA,, Jakob U.

Journal: Nat Commun

PubMed ID: 26787517

Doi: 10.1038/ncomms10357

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Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs.

Authors: Gil-Cruz C, Perez-Shibayama C, Onder L, Chai Q, Cupovic J, Cheng HW, Novkovic M, Lang PA, Geuking MB, McCoy KD, Abe S,, Cui G, Ikuta K, Scandella E, Ludewig B.

Journal: Nat Immunol

PubMed ID: 27798617

Doi: 10.1038/ni.3566

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Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity.

Authors: Coleman JL, Ngo T, Schmidt J, Mrad N, Liew CK, Jones NM, Graham RM, Smith NJ.

Journal: Sci Signal

PubMed ID: 27072655

Doi: 10.1126/scisignal.aad1089

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NOD2 in zebrafish functions in antibacterial and also antiviral responses via NF-κB, and also MDA5, RIG-I and MAVS.

Authors: Zou PF, Chang MX, Li Y, Xue NN, Li JH, Chen SN, Nie P.

Journal: Fish Shellfish Immunol

PubMed ID: 27235368

Doi: 10.1016/j.fsi.2016.05.031

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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery.

Authors: Fumagalli F,,, Noack J,, Bergmann TJ,,, Cebollero E,, Pisoni GB,,, Fasana E,, Fregno I,,, Galli C,, Loi M,, Soldà T,, D'Antuono R,, Raimondi A, Jung M, Melnyk A, Schorr S, Schreiber A, Simonelli L,, Varani L,, Wilson-Zbinden C, Zerbe O, Hofmann K, Peter M, Quadroni M, Zimmermann R, Molinari M,,.

Journal: Nat Cell Biol

PubMed ID: 27749824

Doi: 10.1038/ncb3423

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