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The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.

Authors: Bromberg Kenneth D，Mitchell Taylor R H，Upadhyay Anup K，Jakob Clarissa G，Jhala Manisha A，Comess Kenneth M，Lasko Loren M，Li Conglei，Tuzon Creighton T，Dai Yujia，Li Fengling，Eram Mohammad S，Nuber Alexander，Soni Niru B，Manaves Vlasios，Algire Mikkel A，Sweis Ramzi F，Torrent Maricel，Schotta Gunnar，Sun Chaohong，Michaelides Michael R，Shoemaker Alex R，Arrowsmith Cheryl H，Brown Peter J，Santhakumar Vijayaratnam，Martin Alberto，Rice Judd C，Chiang Gary G，Vedadi Masoud，Barsyte-Lovejoy Dalia，Pappano Willi

Journal: Nat. Chem. Biol.

PubMed ID: 28114273

Doi: 10.1038/nchembio.2282

Products & Services: Peptide Synthesis

Dysregulated Zn homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions， leading to sarcoplasmic reticulum Ca leakage.

Authors: Reilly-O'Donnell Benedict，Robertson Gavin B，Karumbi Angela，McIntyre Connor，Bal Wojciech，Nishi Miyuki，Takeshima Hiroshi，Stewart Alan J，Pitt Samant

Journal: J. Biol. Chem.

PubMed ID: 28630041

Doi: 10.1074/jbc.M117.781708

Products & Services: Peptide Synthesis

In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection.

Authors: Chen Chen，Mangoni Maria Luisa，Di Y P

Journal: Sci Rep

PubMed ID: 28819175

Doi: 10.1038/s41598-017-08361-8

Products & Services: Peptide Synthesis

The Centrocone Houses Cell Cycle Regulatory Factors.

Authors: Naumov Anatoli，Kratzer Stella，Ting Li-Min，Kim Kami，Suvorova Elena S，White Micha

Journal: MBio

PubMed ID: 28830940

Doi: 10.1128/mBio.00579-17

Products & Services: Peptide Synthesis

Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis.

Authors: Hao H, Cao L, Jiang C, Che Y, Zhang S, Takahashi S, Wang G, Gonzalez FJ.

Journal: Cell Metab

PubMed ID: 28380377

Doi: 10.1016/j.cmet.2017.03.007

Products & Services: Peptide Synthesis

Phosphorylation of FE65 at threonine 579 by GSK3β stimulates amyloid precursor protein processing.

Authors: Lee YS, Chow WNV, Lau KF.

Journal: Sci Rep

PubMed ID: 28963516

Doi: 10.1038/s41598-017-12334-2

Products & Services: Peptide Synthesis

Molecular basis for PrimPol recruitment to replication forks by RPA.

Authors: Guilliam TA, Brissett NC, Ehlinger A, Keen BA, Kolesar P, Taylor EM, Bailey LJ, Lindsay HD, Chazin WJ, Doherty AJ.

Journal: Nat Commun

PubMed ID: 28534480

Doi: 10.1038/ncomms15222

Products & Services: Peptide Synthesis

Pathogen-specific deep sequence-coupled biopanning: A method for surveying human antibody responses.

Authors: Frietze KM, Pascale JM, Moreno B, Chackerian B, Peabody DS.

Journal: PLoS ONE

PubMed ID: 28152075

Doi: 10.1371/journal.pone.0171511

Products & Services: Peptide Synthesis

Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha-helical ubiquitin interacting motif.

Authors: Manczyk Noah，Yates Bradley P，Veggiani Gianluca，Ernst Andreas，Sicheri Frank，Sidhu Sachd

Journal: Protein Sci.

PubMed ID: 28276594

Doi: 10.1002/pro.3155

Products & Services: Peptide Synthesis

Combined venetoclax and alvocidib in acute myeloid leukemia.

Authors: Bogenberger James，Whatcott Clifford，Hansen Nanna，Delman Devora，Shi Chang-Xin，Kim Wontak，Haws Hillary，Soh Katherine，Lee Ye Sol，Peterson Peter，Siddiqui-Jain Adam，Weitman Steven，Stewart Keith，Bearss David，Mesa Ruben，Warner Steven，Tibes R

Journal: Oncotarget

PubMed ID: 29291023

Doi: 10.18632/oncotarget.22284

Products & Services: Peptide Synthesis