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Tuning the sensitivity of mechanosensory receptors through histidine scanning

Authors: Yuanhao Wang, Yuhan Wang, Wenjie Yuan, Mingyu Fan, Xiaojing Wang, Anhui Wang, Yanling Bao, Yajing Zhang, Jia Chi Tan, Jianglai Wang, Junshuang Liu, Tianqi Huang, Zixuan Han, Biling Pei, Lijuan Chen, Zhengxu Ren, Xueqing Wang, Lanxin Hu, Siqi Wu, Mengke Pang, Sifan Wang, Zihuan Yang, Jiaze Li, Delian Huang, Shuai Shao, Huairui Yuan, Ling Wu, Yinnian Feng, Penghui Zhou, Guohui Li, Bo Sun, Chenqi Xu, Nicholas R J Gascoigne, Xiang Zhao

Journal: Cell

PubMed ID: 41713420

Doi: 10.1016/j.cell.2025.12.050

Products & Services: Peptide Synthesis

A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

Authors: Qianwen Mu, Haolan Deng, Shuo Li, Xiaoyu An, Xuan Liu, Yue Xi, Hao Liang, Di Sun, Xiaojun Wang, Xue Liu, Gang Liu, Chao Liu

Journal: Nature Communications

PubMed ID: 41917023

Doi: 10.1038/s41467-026-71363-6

Products & Services: Peptide Synthesis Protein Electrophoresis and Western

CRISPR/Cas9-Based Vanadium MXene-Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal-Induced Multi-Effect Synergistic Antitumor Therapy

Authors: Zi-Jian Huang, Feng-Ming Li, Yi-Fan Tu, Ke-Ke Feng, Cheng-Lei Li, Shi-Cheng Tian, Yong-Shan Hu, Jing-Wei Shao, Zhen-Hua Liu

Journal: Advanced Science

PubMed ID: 41818620

Doi: 10.1002/advs.202522535

Products & Services: Peptide Synthesis

mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

Authors: Jiayan Fu, Yaoqi Liu, Zhenyu Zhong, Benyuan Cao, Luna Ran, Zijia Guo, Haiyang Dong, Nengcheng Bao, Rongqing Pan, Jinqiang Wang, Yuanhui Mao, Yongfeng Jin

Journal: Cell Reports Medicine

PubMed ID: 41916290

Doi: 10.1016/j.xcrm.2026.102706

Products & Services: Peptide Synthesis

Semaphorin 3A Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

Authors: Yolanda P rez; Roman Bonet; Miriam Corredor; Cecilia Domingo; Alejandra Moure; ngel Messeguer; Jordi Bujons; Ignacio Alfonso

Journal: Pharmaceuticals

PubMed ID: 34577606

Doi: 10.3390/ph14090906

Products & Services: Peptide Synthesis

Semaphorin 3A Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

Authors: Yolanda P rez; Roman Bonet; Miriam Corredor; Cecilia Domingo; Alejandra Moure; ngel Messeguer; Jordi Bujons; Ignacio Alfonso

Journal: Pharmaceuticals

PubMed ID: 34577606

Doi: 10.3390/ph14090906

Products & Services: Peptide Synthesis

Semaphorin 3A Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

Authors: Yolanda P rez; Roman Bonet; Miriam Corredor; Cecilia Domingo; Alejandra Moure; ngel Messeguer; Jordi Bujons; Ignacio Alfonso

Journal: Pharmaceuticals

PubMed ID: 34577606

Doi: 10.3390/ph14090906

Products & Services: Peptide Synthesis

Elucidating the Molecular Mechanism of 3D1 Antibody Binding to a Swine Enteric Coronavirus Antigen

Authors: Liangminghui Zhang, Ze Liang, Guang Yang, Lei Yan

Journal: Viruses

PubMed ID: 41754551

Doi: 10.3390/v18020208

Products & Services: Peptide Synthesis

Phloretin targeting the 3CLpro Cys144 exhibits broad-spectrum antiviral activity against swine enteric coronavirus

Authors: Jiawei Xiao, Donghua Guo, Xiaoxu Xing, Limin Jiang, Shanshan Qi, Jun Wang, Wenfei Bai, Shiping Yu, Fanbo Shen, Xingyang Guo, Xinglin Wang, Wei Zhou, Hansong Li, Feiyu Zhao, Li Feng, Jialin Zhang, Yaru Xu, Dan Yang, Haixin Liu, Dongbo Sun

Journal: Molecular Therapy

PubMed ID: 41720346

Doi: 10.1016/j.virs.2026.02.011

Products & Services: Peptide Synthesis

In-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus

Authors: Rudra Awdhesh Kumar Mishra; Gothandam Kodiveri Muthukaliannan

Journal: Scientific REPORTS

PubMed ID: 39468175

Doi: 10.1038/s41598-024-76553-0

Products & Services: Peptide Synthesis