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Common helical V1V2 conformations of HIV-1 Envelope expose the α4β7 binding site on intact virions.

Authors: Wibmer CK,,, Richardson SI,, Yolitz J,, Cicala C, Arthos J, Moore PL,,, Morris L,,.

Journal: Nat Commun

PubMed ID: 30367034

Doi: 10.1038/s41467-018-06794-x

Products & Services: Peptide Synthesis

Anti-diuretic activity of a CAPA neuropeptide can compromise Drosophila chill tolerance.

Authors: MacMillan HA, Nazal B, Wali S, Yerushalmi GY, Misyura L, Donini A, Paluzzi JP.

Journal: J Exp Biol

PubMed ID: 30104306

Doi: 10.1242/jeb.185884

Products & Services: Peptide Synthesis

Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 Inhibitor That Accelerates Healing.

Authors: Nguyen TT, Ding D, Wolter WR, Pérez RL, Champion MM, Mahasenan KV, Hesek D, Lee M, Schroeder VA, Jones JI, Lastochkin E, Rose MK, Peterson CE, Suckow MA, Mobashery S, Chang M.

Journal: J Med Chem

PubMed ID: 30212201

Doi: 10.1021/acs.jmedchem.8b01005

Products & Services: Peptide Synthesis

A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3.

Authors: Southam HM, Smith TW, Lyon RL, Liao C, Trevitt CR, Middlemiss LA, Cox FL, Chapman JA, El-Khamisy SF, Hippler M, Williamson MP, Henderson PJF, Poole RK.

Journal: Redox Biol

PubMed ID: 30007887

Doi: 10.1016/j.redox.2018.06.008

Products & Services: Peptide Synthesis

HIF-2α-pVHL complex reveals broad genotype-phenotype correlations in HIF-2α-driven disease.

Authors: Tarade D, Robinson CM,, Lee JE, Ohh M,.

Journal: Nat Commun

PubMed ID: 30135421

Doi: 10.1038/s41467-018-05554-1

Products & Services: Peptide Synthesis

CD70 encoded by modified vaccinia virus Ankara enhances CD8 T-cell-dependent protective immunity in MHC class II-deficient mice

Authors: Bathke B, Pätzold J, Kassub R, Giessel R, Lämmermann K, Hinterberger M, Brinkmann K, Chaplin P, Suter M, Hochrein H, Lauterbach H.

Journal: Immunology

PubMed ID: 29281850

Doi: 10.1111/imm.12884

Products & Services: Peptide Synthesis

Fluoropolymers for intracellular and in vivo protein delivery

Authors: Lv J, He B, Yu J, Wang Y, Wang C, Zhang S, Wang H, Hu J, Zhang Q, Cheng Y.

Journal: Biomaterials

PubMed ID: 30121426

Products & Services: Peptide Synthesis

Sustained Protein Release from a Core-Shell Drug Carrier System Comprised of Mesoporous Nanoparticles and an Injectable Hydrogel.

Authors: Manavitehrani I, Fathi A, Schindeler A,, Dehghani F.

Journal: Macromol Biosci

PubMed ID: 30395416

Products & Services: Peptide Synthesis

The epithelial Na+ channel γ subunit autoinhibitory tract suppresses channel activity by binding the γ subunit's finger-thumb domain interface.

Authors: Balchak DM, Thompson RN, Kashlan OB,.

Journal: J Biol Chem

PubMed ID: 30131333

Doi: 10.1074/jbc.RA118.004362

Products & Services: Peptide Synthesis

Inflammation, mesenchymal stem cells and bone regeneration.

Authors: Liu H, Li D, Zhang Y, Li M.

Journal: Histochem Cell Biol

PubMed ID: 29435765

Products & Services: Peptide Synthesis