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Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain.

Authors: François-Moutal L, Dustrude ET, Wang Y, Brustovetsky T, Dorame A, Ju W, Moutal A, Perez-Miller S, Brustovetsky N, Gokhale V, Khanna M, Khanna R.

Journal: Pain.

PubMed ID: 29847471

Doi: 10.1097/j.pain.0000000000001294

Products & Services: Peptide Synthesis

Specificity profiling of human trypsin-isoenzymes

Authors: Schilling O, Biniossek ML, Mayer B, Elsässer B, Brandstetter H, Goettig P, Stenman UH, Koistinen H.

Journal: Biol Chem.

PubMed ID: 29883318

Doi: 10.1515/hsz-2018-0107.

Products & Services: Peptide Synthesis

Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain

Authors: Yang YM, Arsenault J, Bah A, Krzeminski M, Fekete A, Chao OY, Pacey LK, Wang A, Forman-Kay J, Hampson DR, Wang LY

Journal: Mol Psychiatry

PubMed ID: 30224722

Doi: 10.1038/s41380-018-0240-0

Products & Services: Peptide Synthesis Gene Synthesis

Prediction and validation of the structural features of Ov58GPCR, an immunogenic determinant of Onchocerca volvulus

Authors: Robert Adamu Shey, Stephen Mbigha Ghogomu, Ferdinand Ngale Njume, Lea Olive Tchouate Gainkam, Philippe Poelvoorde, Leon Mutesa, Annie Robert, Perrine Humblet, Jean-Pierre Munyampundu, Joseph Kamgno, Christophe Lelubre, Luc Vanhamme, Jacob Souopgui

Journal: PLoS ONE

PubMed ID: 30256790

Doi: PMC6157839

Products & Services: Gene Synthesis Plasmid DNA Preparation Polyclonal Antibody Services Peptide Synthesis

Uncompromised NK cell activation is essential for virus-specific CTL activity during acute influenza virus infection

Authors: LiuYuan, ZhengJian, LiuYinping, WenLiyan, HuangLei, XiangZheng, LamKwok-Tai, LvAizhen, MaoHuawei, LauYu-Lung, TuWe

Journal: Cell. Mol. Immunol.

PubMed ID: 28413216

Doi: 10.1038/cmi.2017.10

Products & Services: Peptide Synthesis

Prediction and validation of the structural features of Ov58GPCR, an immunogenic determinant of Onchocerca volvulus.

Authors: Shey RA, Ghogomu SM, Njume FN, Gainkam LOT, Poelvoorde P, Mutesa L, Robert A, Humblet P, Munyampundu JP, Kamgno J, Lelubre C, Vanhamme L, Souopgui J.

Journal: PLoS ONE

PubMed ID: 30256790

Products & Services: Peptide Synthesis Polyclonal Antibody Services

Gonococcal MtrE and its surface-expressed Loop 2 are immunogenic and elicit bactericidal antibodies

Authors: WangShuyi，XueJuan，LuPing，NiChunshan，ChengHao，HanRui，van der VeenS

Journal: J. Infect.

PubMed ID: 29902495

Doi: 10.1016/j.jinf.2018.06.001

Products & Services: Peptide Synthesis

The MAP4 Kinase SIK1 Ensures Robust Extracellular ROS Burst and Antibacterial Immunity in Plants

Authors: Zhang M, Chiang YH, Toruño TY, Lee D, Ma M, Liang X, Lal NK, Lemos M, Lu YJ, Ma S, Liu J, Day B, Dinesh-Kumar SP, Dehesh K, Dou D, Zhou JM, Coaker G.

Journal: Cell Host Microbe.

PubMed ID: 30212650

Doi: 10.1016/j.chom.2018.08.007

Products & Services: Peptide Synthesis Catalog Peptides

Self-Assembly of Immune Signals Improves Codelivery to Antigen Presenting Cells and Accelerates Signal Internalization, Processing Kinetics, and Immune Activation.

Authors: Bookstaver ML, Hess KL, Jewell CM

Journal: Small.

PubMed ID: 30146797

Doi: 10.1002/smll.201802202

Products & Services: Peptide Synthesis

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle

Authors: McShan AC, Natarajan K, Kumirov VK, Flores-Solis D, Jiang J, Badstübner M, Toor JS, Bagshaw CR, Kovrigin EL, Margulies DH, Sgourakis NG.

Journal: Nat Chem Biol.

PubMed ID: 29988068

Doi: 10.1038/s41589-018-0096-2

Products & Services: Peptide Synthesis