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Lipid-nucleic acid nanoparticles of novel ionizable lipids for systemic BMP-9 gene delivery to bone-marrow mesenchymal stem cells for osteoinduction.
Authors: VhoraImran,LalaniRohan,BhattPriyanka,PatilSushilkumar,MisraAmbikana
Journal: Int J Pharm
PubMed ID: 30954673
Doi: 10.1016/j.ijpharm.2019.04.006
Products & Services: Peptide Synthesis   
Molecular underpinnings of integrin binding to collagen mimetic peptides containing vascular Ehlers-Danlos syndrome-associated substitutions.
Authors: HoopCody L,KemrajAllysa P,WangBaifan,GahlawatSonal,GodeskyMadison,ZhuJie,WarrenHaley R,CaseDavid A,ShreiberDavid I,Baum
Journal: J. Biol. Chem.
PubMed ID: 31406019
Doi: 10.1074/jbc.RA119.009685
Products & Services: Peptide Synthesis   
Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Authors: WangKaiqian,HoltChristian,LuJocelyn,BrohusMalene,LarsenKamilla Taunsig,OvergaardMichael Toft,WimmerReinhard,Van PetegemF
Journal: Proc. Natl. Acad. Sci. U.S.A.
PubMed ID: 30348784
Doi: 10.1073/pnas.1808733115
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Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface
Authors: Warmack RA1, Boyer DR1, Zee CT1, Richards LS1, Sawaya MR1,2,3, Cascio D1,2,3, Gonen T2,4,5,6, Eisenberg DS1,2,3,4,5, Clarke SG7,8.
Journal: Nat Commun.
PubMed ID: 31350392
Doi: 10.1038/s41467-019-11183-z
Products & Services: Peptide Synthesis   
Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension
Authors: Biancospino M1, Buel GR2, Niño CA1, Maspero E1, di Perrotolo RS1, Raimondi A3, Redlingshöfer L4, Weber J1, Brodsky FM5, Walters KJ6, Polo S7,8.
Journal: Nat Commun.
PubMed ID: 31672988
Doi: 10.1038/s41467-019-12855-6
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In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls
Authors: Jiang W1,2, Birtley JR3,4, Hung SC5,6, Wang W7, Chiou SH8, Macaubas C5,6, Kornum B9, Tian L10, Huang H8, Adler L5,11, Weaver G3, Lu L3, Ilstad-Minnihan A5, Somasundaram S5, Ayyangar S5, Davis MM6,8,12, Stern LJ3, Mellins ED13,14.
Journal: Nat Commun.
PubMed ID: 31748512
Doi: 10.1038/s41467-019-13234-x
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Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation
Authors: Wrobel AG1, Kadlecova Z2, Kamenicky J3, Yang JC4, Herrmann T5, Kelly BT1, McCoy AJ1, Evans PR4, Martin S6, Müller S7, Sroubek F3, Neuhaus D4, Höning S8, Owen DJ1.
Journal: Dev Cell.
PubMed ID: 31430451
Doi: 10.1016/j.devcel.2019.07.017
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Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing
Authors: Blythe EE1, Gates SN2, Deshaies RJ3, Martin A4.
Journal: Structure.
PubMed ID: 31623962
Products & Services: Peptide Synthesis   
Functional recruitment of dynamin requires multimeric interactions for efficient endocytosis
Authors: Rosendale M1,2,3, Van TNN1,2,4, Grillo-Bosch D1,2, Sposini S1,2, Claverie L1,2, Gauthereau I1,2, Claverol S5, Choquet D1,2,6, Sainlos M7,8, Perrais D9,10.
Journal: Nat Commun.
PubMed ID: 31575863
Doi: 10.1038/s41467-019-12434-9
Products & Services: Peptide Synthesis   
PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage
Authors: Raju S1, Verbaro DJ1, Egawa T2.
Journal: Cell Rep.
PubMed ID: 31775026
Products & Services: Peptide Synthesis   
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